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Rezan Güler
Rezan Güler
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Year
Optimal composition and position of histidine-containing tags improves biodistribution of 99mTc-labeled DARPin G3
A Vorobyeva, A Schulga, E Konovalova, R Güler, J Löfblom, M Sandström, ...
Scientific Reports 9 (1), 9405, 2019
622019
Comparative evaluation of two DARPin variants: effect of affinity, size, and label on tumor targeting properties
S Deyev, A Vorobyeva, A Schulga, G Proshkina, R Guler, J Lofblom, ...
Molecular pharmaceutics 16 (3), 995-1008, 2019
502019
Comparison of tumor‑targeting properties of directly and indirectly radioiodinated designed ankyrin repeat protein (DARPin) G3 variants for molecular imaging of HER2
A Vorobyeva, A Sсhulga, E Konovalova, R Güler, B Mitran, J Garousi, ...
International journal of oncology 54 (4), 1209-1220, 2019
302019
Radionuclide imaging of VEGFR2 in glioma vasculature using biparatopic affibody conjugate: proof-of-principle in a murine model
B Mitran, R Güler, FP Roche, E Lindström, RK Selvaraju, F Fleetwood, ...
Theranostics 8 (16), 4462, 2018
292018
Novel affinity binders for neutralization of vascular endothelial growth factor (VEGF) signaling
F Fleetwood, R Güler, E Gordon, S Ståhl, L Claesson-Welsh, J Löfblom
Cellular and Molecular Life Sciences 73, 1671-1683, 2016
282016
Engineering Saccharomyces cerevisiae for the production and secretion of Affibody molecules
V Gast, A Sandegren, F Dunås, S Ekblad, R Güler, S Thorén, ...
Microbial Cell Factories 21 (1), 36, 2022
92022
Increasing thermal stability and improving biodistribution of VEGFR2-binding affibody molecules by a combination of in silico and directed evolution approaches
R Güler, SF Svedmark, A Abouzayed, A Orlova, J Löfblom
Scientific reports 10 (1), 18148, 2020
82020
VEGFR2-Specific Ligands Based on Affibody Molecules Demonstrate Agonistic Effects when Tetrameric in the Soluble Form or Immobilized via Spider Silk
R Güler, N Thatikonda, HA Ghani, M Hedhammar, J Löfblom
ACS Biomaterials Science & Engineering 5 (12), 6474-6484, 2019
52019
Biologic Evaluation of a Heterodimeric HER2-Albumin Targeted Affibody Molecule Produced by Chemo-Enzymatic Peptide Synthesis
Y Liu, R Güler, Y Liao, A Vorobyeva, O Widmark, TJ Meuleman, A Koijen, ...
Pharmaceutics 14 (11), 2519, 2022
42022
Generating a novel bispecific nanobody to enhance antitumor activity
Q Ge, T Sun, Y Bian, X Xiao, J Zhu
Pharmaceutical Fronts 2 (02), e100-e108, 2020
22020
Affibody Molecules Targeting VEGFR2-Two Turns Off and Four Turns On
R Güler
KTH Royal Institute of Technology, 2020
2020
N-terminal position of histidine-glutamate-containing tag improves biodistribution of [Tc-99m] Tc-labeled DARPin G3
A Vorobyeva, A Schulga, E Konovalova, R Güler, J Löfblom, M Sandstrom, ...
European Journal of Nuclear Medicine and Molecular Imaging 46 (SUPPL 1 …, 2019
2019
Artificial VEGFR2-Specific Growth Factors Demonstrate Agonistic Effects in Both Soluble Form and When Immobilized Via Spider Silk
R Güler, N Thatikonda, HA Ghani, M Hedhammar, J Löfblom
2018
In vivo imaging of vascular endothelial growth factor receptor-2 (VEGFR2) expression using biparatopic affibody construct
B Mitran, R Güler, F Roche, E Lindstrom, F Fleetwood, L Claesson-Welsh, ...
Journal of labelled compounds & radiopharmaceuticals 60, S178-S178, 2017
2017
Novel high affinity affibody for radionuclide imaging of VEGFR2 in glioma vasculature: proof-of-principle in murine model
B Mitran, R Guler, FP Roche, E Lindström, R Selvaraju, F Heetwood, ...
European Journal of Nuclear Medicine and Molecular Imaging 44, S239-S239, 2017
2017
Feasibility of in vivo imaging of VEGFR2 expression using high affinity antagonistic biparatopic affibody construct Z (VEGFR2)-Bp (2)
B Mitran, R Güler, E Lindstrom, F Fleetwood, V Tolmachev, S Ståhl, ...
European Journal of Nuclear Medicine and Molecular Imaging 43, S97-S98, 2016
2016
Design och karaktärisering av biparatopa Affibodymolekyler mot VEGFR2
R Güler
2015
Engineering Saccharomyces Cerevisiae for the Production and Secretion of A body Molecules.
V Gast, A Sandegren, F Dunås, S Ekblad, R Güler, S Thorén, ...
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Articles 1–18