| The PDGF family: four gene products form five dimeric isoforms L Fredriksson, H Li, U Eriksson Cytokine & growth factor reviews 15 (4), 197-204, 2004 | 1065 | 2004 |
| Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke EJ Su, L Fredriksson, M Geyer, E Folestad, J Cale, J Andrae, Y Gao, ... Nature medicine 14 (7), 731-737, 2008 | 513 | 2008 |
| Paracrine signaling by platelet-derived growth factor-CC promotes tumor growth by recruitment of cancer-associated fibroblasts C Anderberg, H Li, L Fredriksson, J Andrae, C Betsholtz, X Li, U Eriksson, ... Cancer research 69 (1), 369-378, 2009 | 297 | 2009 |
| Tissue plasminogen activator is a potent activator of PDGF‐CC L Fredriksson, H Li, C Fieber, X Li, U Eriksson The EMBO journal 23 (19), 3793-3802, 2004 | 227 | 2004 |
| PDGF-D is a potent transforming and angiogenic growth factor H Li, L Fredriksson, X Li, U Eriksson Oncogene 22 (10), 1501-1510, 2003 | 201 | 2003 |
| PDGF-C is a proinflammatory cytokine that mediates renal interstitial fibrosis F Eitner, E Bu, C van Roeyen, U Kunter, S Rong, C Seikrit, L Villa, P Boor, ... Journal of the American Society of Nephrology 19 (2), 281-289, 2008 | 152 | 2008 |
| Microglial-mediated PDGF-CC activation increases cerebrovascular permeability during ischemic stroke EJ Su, C Cao, L Fredriksson, I Nilsson, C Stefanitsch, TK Stevenson, ... Acta neuropathologica 134, 585-604, 2017 | 94 | 2017 |
| Structural requirements for activation of latent platelet-derived growth factor CC by tissue plasminogen activator L Fredriksson, M Ehnman, C Fieber, U Eriksson Journal of Biological Chemistry 280 (29), 26856-26862, 2005 | 69 | 2005 |
| Randomized assessment of imatinib in patients with acute ischaemic stroke treated with intravenous thrombolysis N Wahlgren, M Thoren, B Höjeberg, TB Käll, AC Laska, C Sjöstrand, ... Journal of internal medicine 281 (3), 273-283, 2017 | 59 | 2017 |
| Imatinib treatment reduces brain injury in a murine model of traumatic brain injury EJ Su, L Fredriksson, M Kanzawa, S Moore, E Folestad, TK Stevenson, ... Frontiers in cellular neuroscience 9, 385, 2015 | 53 | 2015 |
| tPA modulation of the blood–brain barrier: a unifying explanation for the pleiotropic effects of tPA in the CNS L Fredriksson, DA Lawrence, RL Medcalf Seminars in thrombosis and hemostasis 43 (02), 154-168, 2017 | 52 | 2017 |
| Platelet-derived growth factor C deficiency in C57BL/6 mice leads to abnormal cerebral vascularization, loss of neuroependymal integrity, and ventricular abnormalities L Fredriksson, I Nilsson, EJ Su, J Andrae, H Ding, C Betsholtz, U Eriksson, ... The American journal of pathology 180 (3), 1136-1144, 2012 | 49 | 2012 |
| Tissue plasminogen activator-mediated PDGF signaling and neurovascular coupling in stroke EJ Su, L Fredriksson, GP Schielke, U Eriksson, DA Lawrence Journal of Thrombosis and Haemostasis 7, 155-158, 2009 | 47 | 2009 |
| Pharmacological targeting of the PDGF-CC signaling pathway for blood–brain barrier restoration in neurological disorders SA Lewandowski, L Fredriksson, DA Lawrence, U Eriksson Pharmacology & therapeutics 167, 108-119, 2016 | 46 | 2016 |
| Presymptomatic activation of the PDGF-CC pathway accelerates onset of ALS neurodegeneration SA Lewandowski, I Nilsson, L Fredriksson, P Lönnerberg, L Muhl, ... Acta neuropathologica 131, 453-464, 2016 | 44 | 2016 |
| Identification of a neurovascular signaling pathway regulating seizures in mice L Fredriksson, TK Stevenson, EJ Su, M Ragsdale, S Moore, S Craciun, ... Annals of clinical and translational neurology 2 (7), 722-738, 2015 | 42 | 2015 |
| A role for PDGF-C/PDGFRα signaling in the formation of the meningeal basement membranes surrounding the cerebral cortex J Andrae, L Gouveia, R Gallini, L He, L Fredriksson, I Nilsson, ... Biology open 5 (4), 461-474, 2016 | 31 | 2016 |
| The uPA/uPAR system regulates the bioavailability of PDGF-DD: implications for tumour growth M Ehnman, H Li, L Fredriksson, K Pietras, U Eriksson Oncogene 28 (4), 534-544, 2009 | 30 | 2009 |
| Blocking PDGF-CC signaling ameliorates multiple sclerosis-like neuroinflammation by inhibiting disruption of the blood–brain barrier M Zeitelhofer, MZ Adzemovic, C Moessinger, C Stefanitsch, C Strell, ... Scientific Reports 10 (1), 22383, 2020 | 17 | 2020 |
| Platelet-derived growth factor C, DNA coding therefor, and uses thereof U Eriksson, K Aase, X Li, A Ponten, M Uutela, K Alitalo, A Oestman, ... US Patent App. 09/852,209, 2002 | 14 | 2002 |
