BET and HDAC inhibitors induce similar genes and biological effects and synergize to kill in Myc-induced murine lymphoma J Bhadury, LM Nilsson, S Veppil Muralidharan, LC Green, Z Li, ... Proceedings of the National Academy of Sciences 111 (26), E2721-E2730, 2014 | 250 | 2014 |
Small RNA deep sequencing discriminates subsets of extracellular vesicles released by melanoma cells–Evidence of unique microRNA cargos TR Lunavat, L Cheng, DK Kim, J Bhadury, SC Jang, C Lässer, ... RNA biology 12 (8), 810-823, 2015 | 204 | 2015 |
Melanoma patient-derived xenografts accurately model the disease and develop fast enough to guide treatment decisions BO Einarsdottir, RO Bagge, J Bhadury, H Jespersen, J Mattsson, ... Oncotarget 5 (20), 9609, 2014 | 73 | 2014 |
Global analysis of somatic structural genomic alterations and their impact on gene expression in diverse human cancers B Alaei-Mahabadi, J Bhadury, JW Karlsson, JA Nilsson, E Larsson Proceedings of the National Academy of Sciences 113 (48), 13768-13773, 2016 | 69 | 2016 |
BET bromodomain inhibitors synergize with ATR inhibitors to induce DNA damage, apoptosis, senescence-associated secretory pathway and ER stress in Myc-induced lymphoma cells SV Muralidharan, J Bhadury, LM Nilsson, LC Green, KG McLure, ... Oncogene 35 (36), 4689-4697, 2016 | 62 | 2016 |
Generation of functional organs using a cell-competitive niche in intra-and inter-species rodent chimeras T Nishimura, FP Suchy, J Bhadury, KJ Igarashi, CT Charlesworth, ... Cell Stem Cell 28 (1), 141-149. e3, 2021 | 42 | 2021 |
BET bromodomain inhibitors synergize with ATR inhibitors in melanoma SV Muralidharan, BO Einarsdottir, J Bhadury, MF Lindberg, J Wu, ... Cell death & disease 8 (8), e2982-e2982, 2017 | 20 | 2017 |
Generating human artery and vein cells from pluripotent stem cells highlights the arterial tropism of Nipah and Hendra viruses LT Ang, AT Nguyen, KJ Liu, A Chen, X Xiong, M Curtis, RM Martin, ... Cell 185 (14), 2523-2541. e30, 2022 | 17 | 2022 |
Cancer differentiating agent hexamethylene bisacetamide inhibits BET bromodomain proteins LM Nilsson, LC Green, SV Muralidharan, D Demir, M Welin, J Bhadury, ... Cancer Research 76 (8), 2376-2383, 2016 | 15 | 2016 |
Identification of tumorigenic and therapeutically actionable mutations in transplantable mouse tumor cells by exome sequencing J Bhadury, MD Lopez, SV Muralidharan, LM Nilsson, JA Nilsson Oncogenesis 2 (4), e44-e44, 2013 | 15 | 2013 |
Hypoxia-regulated gene expression explains differences between melanoma cell line-derived xenografts and patient-derived xenografts J Bhadury, BO Einarsdottir, A Podraza, RO Bagge, U Stierner, L Ny, ... Oncotarget 7 (17), 23801, 2016 | 12 | 2016 |
Physioxia improves the selectivity of hematopoietic stem cell expansion cultures KJ Igarashi, I Kucinski, YY Chan, TK Tan, HM Khoo, D Kealy, J Bhadury, ... Blood Advances 7 (14), 3366-3377, 2023 | 7 | 2023 |
Chimpanzee and pig-tailed macaque iPSCs: Improved culture and generation of primate cross-species embryos M Roodgar, FP Suchy, LH Nguyen, VK Bajpai, R Sinha, JG Vilches-Moure, ... Cell reports 40 (9), 2022 | 6 | 2022 |
Streamlined and quantitative detection of chimerism using digital PCR FP Suchy, T Nishimura, S Seki, AC Wilkinson, M Higuchi, I Hsu, J Zhang, ... Scientific Reports 12 (1), 10223, 2022 | 5 | 2022 |
Cross-species blastocyst chimerism between nonhuman primates using iPSCs M Roodgar, FP Suchy, V Bajpai, JG Viches-Moure, J Bhadury, ... bioRxiv, 635250, 2019 | 5 | 2019 |
Activated HoxB4-induced hematopoietic stem cells from murine pluripotent stem cells via long-term programming K Izawa, S Yamazaki, HJ Becker, J Bhadury, T Kakegawa, M Sakaguchi, ... Experimental Hematology 89, 68-79. e7, 2020 | 3 | 2020 |
Large-scale in vivo CRISPR screens identify SAGA complex members as a key regulators of HSC lineage commitment and aging MS Haney, A Shankar, I Hsu, M Miyauchi, R Pálovics, HM Khoo, ... bioRxiv, 2022.07. 22.501030, 2022 | 1 | 2022 |
Streamlined and quantitative detection of chimerism in mouse tissue using digital PCR FP Suchy, T Nishimura, AC Wilkinson, M Higuchi, J Bhadury, H Nakauchi bioRxiv, 2020.11. 04.368944, 2020 | 1 | 2020 |
Trp53 mutational status correlates with tumorigenicity in TRAMP-C mouse prostate cancer cell lines J Bhadury, LM Nilsson, MD López, JA Nilsson Matters 2 (8), e201607000007, 2016 | 1 | 2016 |
Abstract B38: Melanoma patient-derived xenografts accurately models the disease and develop fast enough to guide treatment decisions BO Einarsdottir, RO Bagge, J Bhadury, H Jespersen, LM Nilsson, ... Cancer Research 75 (14_Supplement), B38-B38, 2015 | 1 | 2015 |