| Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae SJ Lin, PA Defossez, L Guarente Science 289 (5487), 2126-2128, 2000 | 2236 | 2000 |
| Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration SJ Lin, M Kaeberlein, AA Andalis, LA Sturtz, PA Defossez, VC Culotta, ... Nature 418 (6895), 344-348, 2002 | 1297 | 2002 |
| Elimination of replication block protein Fob1 extends the life span of yeast mother cells PA Defossez, R Prusty, M Kaeberlein, SJ Lin, P Ferrigno, PA Silver, ... Molecular cell 3 (4), 447-455, 1999 | 472 | 1999 |
| A family of human zinc finger proteins that bind methylated DNA and repress transcription GJP Filion, S Zhenilo, S Salozhin, D Yamada, E Prokhortchouk, ... Molecular and cellular biology 26 (1), 169-181, 2006 | 439 | 2006 |
| Born to bind: the BTB protein–protein interaction domain R Perez‐Torrado, D Yamada, PA Defossez Bioessays 28 (12), 1194-1202, 2006 | 288 | 2006 |
| Identification of oncogenic microRNA-17-92/ZBTB4/specificity protein axis in breast cancer K Kim, G Chadalapaka, SO Lee, D Yamada, X Sastre-Garau, ... Oncogene 31 (8), 1034-1044, 2012 | 206 | 2012 |
| Effects of Mutations in DNA Repair Genes on Formation of Ribosomal DNA Circles and Life Span in Saccharomyces cerevisiae PU Park, PA Defossez, L Guarente Molecular and cellular biology 19 (5), 3848-3856, 1999 | 194 | 1999 |
| Androgen receptor-Ets protein interaction is a novel mechanism for steroid hormone-mediated down-modulation of matrix metalloproteinase expression J Schneikert, H Peterziel, PA Defossez, H Klocker, Y de Launoit, ... Journal of Biological Chemistry 271 (39), 23907-23913, 1996 | 189 | 1996 |
| Methylation of DNA ligase 1 by G9a/GLP recruits UHRF1 to replicating DNA and regulates DNA methylation L Ferry, A Fournier, T Tsusaka, G Adelmant, T Shimazu, S Matano, ... Molecular cell 67 (4), 550-565. e5, 2017 | 178 | 2017 |
| Differential expression patterns of the PEA3 group transcription factors through murine embryonic development A Chotteau-Lelièvre, X Desbiens, H Pelczar, PA Defossez, Y de Launoit Oncogene 15 (8), 937-952, 1997 | 176 | 1997 |
| The cell biology of DNA methylation in mammals E Prokhortchouk, PA Defossez Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1783 (11), 2167-2173, 2008 | 152 | 2008 |
| Sequence-specific recognition of methylated DNA by human zinc-finger proteins N Sasai, M Nakao, PA Defossez Nucleic acids research 38 (15), 5015-5022, 2010 | 145 | 2010 |
| Molecular cloning and characterization of human ERM, a new member of the Ets family closely related to mouse PEA3 and ER81 transcription factors. D Monté, JL Baert, PA Defossez, Y de Launoit, D Stéhelin Oncogene 9 (5), 1397-1406, 1994 | 137 | 1994 |
| The human enhancer blocker CTC-binding factor interacts with the transcription factor Kaiso PA Defossez, KF Kelly, GJP Filion, R Pérez-Torrado, F Magdinier, ... Journal of Biological Chemistry 280 (52), 43017-43023, 2005 | 131 | 2005 |
| On how mammalian transcription factors recognize methylated DNA BA Buck-Koehntop, PA Defossez Epigenetics 8 (2), 131-137, 2013 | 129 | 2013 |
| The role of methyl-binding proteins in chromatin organization and epigenome maintenance A Fournier, N Sasai, M Nakao, PA Defossez Briefings in functional genomics 11 (3), 251-264, 2012 | 123 | 2012 |
| The human proteins MBD5 and MBD6 associate with heterochromatin but they do not bind methylated DNA S Laget, M Joulie, F Le Masson, N Sasai, E Christians, S Pradhan, ... PloS one 5 (8), e11982, 2010 | 122 | 2010 |
| Many paths to one goal? The proteins that recognize methylated DNA in eukaryotes. N Sasai, PA Defossez International Journal of Developmental Biology 53, 2009 | 121 | 2009 |
| Zbtb4 represses transcription of P21CIP1 and controls the cellular response to p53 activation A Weber, J Marquardt, D Elzi, N Forster, S Starke, A Glaum, D Yamada, ... The EMBO journal 27 (11), 1563-1574, 2008 | 121 | 2008 |
| Biological functions of methyl-CpG-binding proteins PA Defossez, I Stancheva Progress in molecular biology and translational science 101, 377-398, 2011 | 117 | 2011 |
Guillaume FilionUniversity of Toronto ScarboroughVerified email at utoronto.ca
