Frank Westermann

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Benedikt BrorsDivision of Applied Bioinformatics, German Cancer Research Center DKFZ HeidelbergVerified email at dkfz.de
Jo Vandesompeleprofessor in functional cancer genomics and applied bioinformaticsVerified email at ugent.be
Javed KhanDeputy Branch Chief Genetics Branch, Senior Investigator, Center for Cancer Research, NCI, NIHVerified email at mail.nih.gov
Katleen De Preterfull research professor, Ghent UniversityVerified email at ugent.be
Pieter Mestdaghpostdoctoral fellow, Ghent UniversityVerified email at ugent.be
Axel BennerDKFZ HeidelbergVerified email at dkfz-heidelberg.de
Stefan M. PfisterProfessor of Pediatrics, Hopp-Children´s Cancer Center Heidelberg (KiTZ)Verified email at kitz-heidelberg.de
Roland EilsProfessor for Digital Health, Charité-Universitätsmedizin Berlin and Berlin Institute of HealthVerified email at charite.de
Marcel KoolPI, Hopp Children's Cancer Center Heidelberg & Princess Maxima Center Pediatric Oncology UtrechtVerified email at dkfz.de
Sven BilkeIllumina Inc.Verified email at illumina.com
Annette Kopp-SchneiderHead, Division of Biostatistics, German Cancer Research Center (DKFZ), HeidelbergVerified email at dkfz.de
D CatchpooleHead, Tumour Bank, The Children's Hospital at WestmeadVerified email at health.nsw.gov.au
Markus RingnérScience for Life Laboratory and Lund UniversityVerified email at scilifelab.se
Carsten PetersonProfessor, Computational Biology, Theoretical Physics, Lund UniversityVerified email at thep.lu.se
Lao H SaalAssociate Professor, Lund UniversityVerified email at med.lu.se
Melinda HalaszAssistant Professor, UCD School of MedicineVerified email at ucd.ie
Thomas HielscherDKFZ, German Cancer Research Center, Division of BiostatisticsVerified email at dkfz.de
Li MaNylene Eckles Distinguished Professor, The University of Texas MD Anderson Cancer CenterVerified email at mdanderson.org
Robert A. WeinbergMITVerified email at wi.mit.edu
Sven LindnerUniversity Hospital EssenVerified email at ruhr-uni-bochum.de

Frank Westermann

Associate Professor of Tumor Biology and Personalized Medicine

Verified email at dkfz.de - Homepage

Childhood Cancer Neuroendocrine Development Oncogenes Epigenetics Personalized Oncology


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Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks J Khan, JS Wei, M Ringner, LH Saal, M Ladanyi, F Westermann, ... Nature medicine 7 (6), 673-679, 2001	3585	2001
miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis L Ma, J Young, H Prabhala, E Pan, P Mestdagh, D Muth, ... Nature cell biology 12 (3), 247-256, 2010	1667	2010
The landscape of genomic alterations across childhood cancers SN Gröbner, BC Worst, J Weischenfeldt, I Buchhalter, K Kleinheinz, ... Nature 555 (7696), 321-327, 2018	1438	2018
A novel and universal method for microRNA RT-qPCR data normalization P Mestdagh, P Van Vlierberghe, A De Weer, D Muth, F Westermann, ... Genome biology 10, 1-10, 2009	1223	2009
The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models L Shi, G Campbell, WD Jones, F Campagne, Z Wen, SJ Walker, Z Su, ... Nature biotechnology 28 (8), 827-838, 2010	883	2010
Telomerase activation by genomic rearrangements in high-risk neuroblastoma M Peifer, F Hertwig, F Roels, D Dreidax, M Gartlgruber, R Menon, ... Nature 526 (7575), 700-704, 2015	642	2015
Histone deacetylase 8 in neuroblastoma tumorigenesis I Oehme, HE Deubzer, D Wegener, D Pickert, JP Linke, B Hero, ... Clinical Cancer Research 15 (1), 91-99, 2009	470	2009
Neuroblastoma: biology and molecular and chromosomal pathology M Schwab, F Westermann, B Hero, F Berthold The lancet oncology 4 (8), 472-480, 2003	413	2003
Mutational dynamics between primary and relapse neuroblastomas A Schramm, J Köster, Y Assenov, K Althoff, M Peifer, E Mahlow, ... Nature genetics 47 (8), 872-877, 2015	386	2015
Next-generation personalised medicine for high-risk paediatric cancer patients–The INFORM pilot study BC Worst, CM van Tilburg, GP Balasubramanian, P Fiesel, R Witt, ... European journal of cancer 65, 91-101, 2016	336	2016
A mechanistic classification of clinical phenotypes in neuroblastoma S Ackermann, M Cartolano, B Hero, A Welte, Y Kahlert, A Roderwieser, ... Science 362 (6419), 1165-1170, 2018	321	2018
Customized oligonucleotide microarray gene expression–based classification of neuroblastoma patients outperforms current clinical risk stratification A Oberthuer, F Berthold, P Warnat, B Hero, Y Kahlert, R Spitz, K Ernestus, ... Journal of clinical oncology 24 (31), 5070-5078, 2006	315	2006
Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas F Westermann, D Muth, A Benner, T Bauer, KO Henrich, A Oberthuer, ... Genome biology 9, 1-14, 2008	298	2008
Heterozygous mutations in ANKH, the human ortholog of the mouse progressive ankylosis gene, result in craniometaphyseal dysplasia P Nürnberg, H Thiele, D Chandler, W Höhne, ML Cunningham, H Ritter, ... Nature genetics 28 (1), 37-41, 2001	275	2001
Prediction of clinical outcome using gene expression profiling and artificial neural networks for patients with neuroblastoma JS Wei, BT Greer, F Westermann, SM Steinberg, CG Son, QR Chen, ... Cancer research 64 (19), 6883-6891, 2004	258	2004
Hox-C9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastoma H Kocak, S Ackermann, B Hero, Y Kahlert, A Oberthuer, D Juraeva, ... Cell death & disease 4 (4), e586-e586, 2013	249	2013
Genetic parameters of neuroblastomas F Westermann, M Schwab Cancer letters 184 (2), 127-147, 2002	233	2002
Single-cell transcriptomic analyses provide insights into the developmental origins of neuroblastoma S Jansky, AK Sharma, V Körber, A Quintero, UH Toprak, EM Wecht, ... Nature genetics 53 (5), 683-693, 2021	209	2021
Targeting MYCN-driven transcription by BET-bromodomain inhibition A Henssen, K Althoff, A Odersky, A Beckers, R Koche, F Speleman, ... Clinical Cancer Research 22 (10), 2470-2481, 2016	192	2016
FSTL5 Is a Marker of Poor Prognosis in Non-WNT/Non-SHH Medulloblastoma M Remke, T Hielscher, A Korshunov, PA Northcott, S Bender, M Kool, ... Journal of Clinical Oncology 29 (29), 3852-3861, 2011	188	2011

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