Zach Gerhart-Hines
Zach Gerhart-Hines
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Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1α
M Lagouge, C Argmann, Z Gerhart-Hines, H Meziane, C Lerin, F Daussin, ...
Cell 127 (6), 1109-1122, 2006
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
C Cantó, Z Gerhart-Hines, JN Feige, M Lagouge, L Noriega, JC Milne, ...
Nature 458 (7241), 1056-1060, 2009
Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC‐1α
Z Gerhart‐Hines, JT Rodgers, O Bare, C Lerin, SH Kim, R Mostoslavsky, ...
The EMBO journal 26 (7), 1913-1923, 2007
Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment
ZT Schafer, AR Grassian, L Song, Z Jiang, Z Gerhart-Hines, HY Irie, ...
Nature 461 (7260), 109-113, 2009
Metabolic adaptations through the PGC-1α and SIRT1 pathways
JT Rodgers, C Lerin, Z Gerhart-Hines, P Puigserver
FEBS letters 582 (1), 46-53, 2008
The cAMP/PKA pathway rapidly activates SIRT1 to promote fatty acid oxidation independently of changes in NAD+
Z Gerhart-Hines, JE Dominy Jr, SM Blättler, MP Jedrychowski, AS Banks, ...
Molecular cell 44 (6), 851-863, 2011
A metabolic prosurvival role for PML in breast cancer
A Carracedo, D Weiss, AK Leliaert, M Bhasin, VCJ De Boer, G Laurent, ...
The Journal of clinical investigation 122 (9), 3088-3100, 2012
The nuclear receptor Rev-erbα controls circadian thermogenic plasticity
Z Gerhart-Hines, D Feng, MJ Emmett, LJ Everett, E Loro, ER Briggs, ...
Nature 503 (7476), 410-413, 2013
Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells
G Suchankova, LE Nelson, Z Gerhart-Hines, M Kelly, MS Gauthier, ...
Biochemical and biophysical research communications 378 (4), 836-841, 2009
Nutrient-dependent regulation of PGC-1α's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5
JE Dominy Jr, Y Lee, Z Gerhart-Hines, P Puigserver
Biochimica et biophysica acta (BBA)-proteins and proteomics 1804 (8), 1676-1683, 2010
Circadian enhancers coordinate multiple phases of rhythmic gene transcription in vivo
B Fang, LJ Everett, J Jager, E Briggs, SM Armour, D Feng, A Roy, ...
Cell 159 (5), 1140-1152, 2014
Oleic acid stimulates complete oxidation of fatty acids through protein kinase A-dependent activation of SIRT1-PGC1α complex
JH Lim, Z Gerhart-Hines, JE Dominy, Y Lee, S Kim, M Tabata, YK Xiang, ...
Journal of Biological Chemistry 288 (10), 7117-7126, 2013
Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge
MJ Emmett, HW Lim, J Jager, HJ Richter, M Adlanmerini, LC Peed, ...
Nature 546 (7659), 544-548, 2017
Circadian metabolism in the light of evolution
Z Gerhart-Hines, MA Lazar
Endocrine reviews 36 (3), 289-304, 2015
Kynurenic acid and Gpr35 regulate adipose tissue energy homeostasis and inflammation
LZ Agudelo, DMS Ferreira, I Cervenka, G Bryzgalova, S Dadvar, ...
Cell metabolism 27 (2), 378-392. e5, 2018
Behavioral changes and dopaminergic dysregulation in mice lacking the nuclear receptor Rev-erbα
J Jager, WT O'Brien, J Manlove, EN Krizman, B Fang, Z Gerhart-Hines, ...
Molecular endocrinology 28 (4), 490-498, 2014
Cardiolipin synthesis in brown and beige fat mitochondria is essential for systemic energy homeostasis
EG Sustarsic, T Ma, MD Lynes, M Larsen, I Karavaeva, JF Havelund, ...
Cell metabolism 28 (1), 159-174. e11, 2018
Cold-activated lipid dynamics in adipose tissue highlights a role for cardiolipin in thermogenic metabolism
MD Lynes, F Shamsi, EG Sustarsic, LO Leiria, CH Wang, SC Su, ...
Cell reports 24 (3), 781-790, 2018
A diurnal rhythm in brown adipose tissue causes rapid clearance and combustion of plasma lipids at wakening
R van den Berg, S Kooijman, R Noordam, A Ramkisoensing, ...
Cell reports 22 (13), 3521-3533, 2018
Rev‐erbα and the circadian transcriptional regulation of metabolism
Z Gerhart‐Hines, MA Lazar
Diabetes, Obesity and Metabolism 17, 12-16, 2015
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Artiklar 1–20