| Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474 ACM van Esbroeck, APA Janssen, AB Cognetta III, D Ogasawara, ... Science 356 (6342), 1084-1087, 2017 | 315 | 2017 |
| Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity M Soethoudt, U Grether, J Fingerle, TW Grim, F Fezza, L De Petrocellis, ... Nature communications 8 (1), 13958, 2017 | 311 | 2017 |
| 2-Arachidonoylglycerol: A signaling lipid with manifold actions in the brain MP Baggelaar, M Maccarrone, M van der Stelt Progress in Lipid Research 71, 1-17, 2018 | 203 | 2018 |
| Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition D Ogasawara, H Deng, A Viader, MP Baggelaar, A Breman, H den Dulk, ... Proceedings of the National Academy of Sciences 113 (1), 26-33, 2016 | 166 | 2016 |
| Development of an activity-based probe and in silico design reveal highly selective inhibitors for diacylglycerol lipase-α in brain MP Baggelaar, FJ Janssen, ACM van Esbroeck, H den Dulk, M Allarà, ... Angew Chem Int Ed Engl 52 (46), 12081-12085, 2013 | 108 | 2013 |
| Highly selective, reversible inhibitor identified by comparative chemoproteomics modulates diacylglycerol lipase activity in neurons MP Baggelaar, PJP Chameau, V Kantae, J Hummel, KL Hsu, F Janssen, ... Journal of the American Chemical Society 137 (27), 8851-8857, 2015 | 92 | 2015 |
| The novel, orally available and peripherally restricted selective cannabinoid CB2 receptor agonist LEI‐101 prevents cisplatin‐induced nephrotoxicity P Mukhopadhyay, M Baggelaar, K Erdelyi, Z Cao, R Cinar, F Fezza, ... British journal of pharmacology 173 (3), 446-458, 2016 | 78 | 2016 |
| Mapping in vivo target interaction profiles of covalent inhibitors using chemical proteomics with label-free quantification EJ van Rooden, BI Florea, H Deng, MP Baggelaar, ACM van Esbroeck, ... Nature protocols 13 (4), 752-767, 2018 | 65 | 2018 |
| Discovery of Glycine Sulfonamides as Dual Inhibitors of sn-1-Diacylglycerol Lipase α and α/β-Hydrolase Domain 6 FJ Janssen, H Deng, MP Baggelaar, M Allarà, T van der Wel, H den Dulk, ... Journal of Medicinal Chemistry 57 (15), 6610-6622, 2014 | 45 | 2014 |
| Triazole ureas act as diacylglycerol lipase inhibitors and prevent fasting-induced refeeding H Deng, S Kooijman, AMCH van den Nieuwendijk, D Ogasawara, ... Journal of Medicinal Chemistry 60 (1), 428-440, 2017 | 44 | 2017 |
| A natural substrate-based fluorescence assay for inhibitor screening on diacylglycerol lipase α T van Der Wel, FJ Janssen, MP Baggelaar, H Deng, H den Dulk, ... Journal of lipid research 56 (4), 927-935, 2015 | 42 | 2015 |
| Chemical proteomics maps brain region specific activity of endocannabinoid hydrolases MP Baggelaar, ACM van Esbroeck, EJ van Rooden, BI Florea, ... ACS chemical biology 12 (3), 852-861, 2017 | 40 | 2017 |
| Total synthesis of the triglycosyl phenolic glycolipid PGL-tb1 from Mycobacterium tuberculosis S Barroso, R Castelli, MP Baggelaar, D Geerdink, B ter Horst, ... Angewandte Chemie-International Edition 51 (47), 11774-11777, 2012 | 35 | 2012 |
| ABHD2 inhibitor identified by activity-based protein profiling reduces acrosome reaction MP Baggelaar, H den Dulk, BI Florea, D Fazio, N Bernabò, M Raspa, ... ACS chemical biology 14 (10), 2295-2304, 2019 | 30 | 2019 |
| Activity-based protein profiling identifies α-ketoamides as inhibitors for phospholipase A2 group XVI J Zhou, ED Mock, A Martella, V Kantae, X Di, L Burggraaff, MP Baggelaar, ... ACS Chemical Biology 14 (2), 164-169, 2019 | 30 | 2019 |
| Development of an acid ceramidase activity-based probe CMJ Ouairy, MJ Ferraz, RG Boot, MP Baggelaar, M van der Stelt, ... Chemical communications 51 (28), 6161-6163, 2015 | 25 | 2015 |
| Comprehensive Analysis of Structure–Activity Relationships of α-Ketoheterocycles as sn-1-Diacylglycerol Lipase α Inhibitors FJ Janssen, MP Baggelaar, JJA Hummel, HS Overkleeft, BF Cravatt, ... Journal of medicinal chemistry 58 (24), 9742-9753, 2015 | 24 | 2015 |
| Recent advancements in mass spectrometry–based tools to investigate newly synthesized proteins W van Bergen, AJR Heck, MP Baggelaar Current Opinion in Chemical Biology 66, 102074, 2022 | 23 | 2022 |
| Catalytic asymmetric total synthesis of (S)-(−)-zearalenone, a novel lipoxygenase inhibitor MP Baggelaar, Y Huang, BL Feringa, FJ Dekker, AJ Minnaard Bioorganic & medicinal chemistry 21 (17), 5271-5274, 2013 | 17 | 2013 |
| Chiral disubstituted piperidinyl ureas: a class of dual diacylglycerol lipase-α and ABHD6 inhibitors H Deng, T van der Wel, RJ van den Berg, AMCH van den Nieuwendijk, ... MedChemComm 8 (5), 982-988, 2017 | 13 | 2017 |
Mario van der SteltLeiden UniversityVerified email at chem.leidenuniv.nl
