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Matthew J Longley
Matthew J Longley
NIEHS
Verified email at niehs.nih.gov
Title
Cited by
Cited by
Year
Hypermutability and mismatch repair deficiency in RER+ tumor cells
R Parsons, GM Li, MJ Longley, W Fang, N Papadopoulos, J Jen, ...
Cell 75 (6), 1227-1236, 1993
13671993
Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumor cells
JT Drummond, GM Li, MJ Longley, P Modrich
Science 268 (5219), 1909-1912, 1995
7801995
An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair.
A Kat, WG Thilly, WH Fang, MJ Longley, GM Li, P Modrich
Proceedings of the National Academy of Sciences 90 (14), 6424-6428, 1993
5561993
Mismatch repair deficiency in phenotypically normal human cells
R Parsons, GM Li, M Longley, P Modrich, B Liu, T Berk, SR Hamilton, ...
Science 268 (5211), 738-740, 1995
4161995
DNA polymerase γ in mitochondrial DNA replication and repair
MA Graziewicz, MJ Longley, WC Copeland
Chemical reviews 106 (2), 383-405, 2006
3472006
DNA polymerase δ is required for human mismatch repair in vitro
MJ Longley, AJ Pierce, P Modrich
Journal of Biological Chemistry 272 (16), 10917-10921, 1997
3241997
The fidelity of human DNA polymerase γ with and without exonucleolytic proofreading and the p55 accessory subunit
MJ Longley, D Nguyen, TA Kunkel, WC Copeland
Journal of Biological Chemistry 276 (42), 38555-38562, 2001
2982001
The mitochondrial p55 accessory subunit of human DNA polymerase γ enhances DNA binding, promotes processive DNA synthesis, and confers N-ethylmaleimide resistance
SE Lim, MJ Longley, WC Copeland
Journal of Biological Chemistry 274 (53), 38197-38203, 1999
2901999
Mutant POLG2 disrupts DNA polymerase γ subunits and causes progressive external ophthalmoplegia
MJ Longley, S Clark, CYW Man, G Hudson, SE Durham, RW Taylor, ...
The American Journal of Human Genetics 78 (6), 1026-1034, 2006
2842006
Identification of 5′-deoxyribose phosphate lyase activity in human DNA polymerase γ and its role in mitochondrial base excision repair in vitro
MJ Longley, R Prasad, DK Srivastava, SH Wilson, WC Copeland
Proceedings of the National Academy of Sciences 95 (21), 12244-12248, 1998
2761998
DNA precursor asymmetries in mammalian tissue mitochondria and possible contribution to mutagenesis through reduced replication fidelity
S Song, ZF Pursell, WC Copeland, MJ Longley, TA Kunkel, CK Mathews
Proceedings of the National Academy of Sciences 102 (14), 4990-4995, 2005
2412005
Characterization of the native and recombinant catalytic subunit of human DNA polymerase γ: identification of residues critical for exonuclease activity and dideoxynucleotide …
MJ Longley, PA Ropp, SE Lim, WC Copeland
Biochemistry 37 (29), 10529-10539, 1998
2151998
Long patch base excision repair in mammalian mitochondrial genomes
B Szczesny, AW Tann, MJ Longley, WC Copeland, S Mitra
Journal of Biological Chemistry 283 (39), 26349-26356, 2008
1882008
Consequences of mutations in human DNA polymerase γ
MJ Longley, MA Graziewicz, RJ Bienstock, WC Copeland
Gene 354, 125-131, 2005
1722005
Active site mutation in DNA polymerase γ associated with progressive external ophthalmoplegia causes error-prone DNA synthesis
MV Ponamarev, MJ Longley, D Nguyen, TA Kunkel, WC Copeland
Journal of Biological Chemistry 277 (18), 15225-15228, 2002
1692002
The common A467T mutation in the human mitochondrial DNA polymerase (POLG) compromises catalytic efficiency and interaction with the accessory subunit
SSL Chan, MJ Longley, WC Copeland
Journal of Biological Chemistry 280 (36), 31341-31346, 2005
1632005
Structure-function defects of human mitochondrial DNA polymerase in autosomal dominant progressive external ophthalmoplegia
MA Graziewicz, MJ Longley, RJ Bienstock, M Zeviani, WC Copeland
Nature structural & molecular biology 11 (8), 770-776, 2004
1572004
Mitochondrial genome maintenance in health and disease
WC Copeland, MJ Longley
DNA repair 19, 190-198, 2014
1562014
POS5 Gene of Saccharomyces cerevisiae Encodes a Mitochondrial NADH Kinase Required for Stability of Mitochondrial DNA
MK Strand, GR Stuart, MJ Longley, MA Graziewicz, OC Dominick, ...
Eukaryotic Cell 2 (4), 809-820, 2003
1292003
Characterization of the 5′ to 3′ exonuclease associated with Thermus aquaticus DNA polymerase
MJ Longley, SE Bennett, DW Mosbaugh
Nucleic acids research 18 (24), 7317-7322, 1990
1281990
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