| Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARγ by Cdk5 JH Choi, AS Banks, JL Estall, S Kajimura, P Boström, D Laznik, JL Ruas, ... Nature 466 (7305), 451-456, 2010 | 985 | 2010 |
| Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation JH Choi, AS Banks, TM Kamenecka, SA Busby, MJ Chalmers, N Kumar, ... Nature 477 (7365), 477-481, 2011 | 592 | 2011 |
| Molecular mimicry regulates ABA signaling by SnRK2 kinases and PP2C phosphatases FF Soon, LM Ng, XE Zhou, GM West, A Kovach, MHE Tan, ... Science 335 (6064), 85-88, 2012 | 540 | 2012 |
| Partial agonists activate PPARγ using a helix 12 independent mechanism JB Bruning, MJ Chalmers, S Prasad, SA Busby, TM Kamenecka, Y He, ... Structure 15 (10), 1258-1271, 2007 | 397 | 2007 |
| Probing protein ligand interactions by automated hydrogen/deuterium exchange mass spectrometry MJ Chalmers, SA Busby, BD Pascal, Y He, CL Hendrickson, AG Marshall, ... Analytical chemistry 78 (4), 1005-1014, 2006 | 324 | 2006 |
| HDX workbench: software for the analysis of H/D exchange MS data BD Pascal, S Willis, JL Lauer, RR Landgraf, GM West, D Marciano, ... Journal of the American Society for Mass Spectrometry 23 (9), 1512-1521, 2012 | 301 | 2012 |
| Combined electron capture and infrared multiphoton dissociation for multistage MS/MS in a Fourier transform ion cyclotron resonance mass spectrometer K Håkansson, MJ Chalmers, JP Quinn, MA McFarland, CL Hendrickson, ... Analytical chemistry 75 (13), 3256-3262, 2003 | 272 | 2003 |
| Differential hydrogen/deuterium exchange mass spectrometry analysis of protein–ligand interactions MJ Chalmers, SA Busby, BD Pascal, GM West, PR Griffin Expert review of proteomics 8 (1), 43-59, 2011 | 269 | 2011 |
| Modulation of Retinoic Acid Receptor-related Orphan Receptor α and γ Activity by 7-Oxygenated Sterol Ligands 2 Y Wang, N Kumar, LA Solt, TI Richardson, LM Helvering, C Crumbley, ... Journal of Biological Chemistry 285 (7), 5013-5025, 2010 | 232 | 2010 |
| DNA binding alters coactivator interaction surfaces of the intact VDR–RXR complex J Zhang, MJ Chalmers, KR Stayrook, LL Burris, Y Wang, SA Busby, ... Nature structural & molecular biology 18 (5), 556-563, 2011 | 226 | 2011 |
| Ligand and receptor dynamics contribute to the mechanism of graded PPARγ agonism TS Hughes, MJ Chalmers, S Novick, DS Kuruvilla, MR Chang, ... Structure 20 (1), 139-150, 2012 | 169 | 2012 |
| Ligand-dependent perturbation of the conformational ensemble for the GPCR β2 adrenergic receptor revealed by HDX GM West, EYT Chien, V Katritch, J Gatchalian, MJ Chalmers, RC Stevens, ... Structure 19 (10), 1424-1432, 2011 | 156 | 2011 |
| Advances in mass spectrometry for proteome analysis MJ Chalmers, SJ Gaskell Current Opinion in Biotechnology 11 (4), 384-390, 2000 | 155 | 2000 |
| Identification and mechanism of 10-carbon fatty acid as modulating ligand of peroxisome proliferator-activated receptors RRV Malapaka, SK Khoo, J Zhang, JH Choi, XE Zhou, Y Xu, Y Gong, J Li, ... Journal of Biological Chemistry 287 (1), 183-195, 2012 | 154 | 2012 |
| Dynamics of the β2-Adrenergic G-Protein Coupled Receptor Revealed by Hydrogen−Deuterium Exchange X Zhang, EYT Chien, MJ Chalmers, BD Pascal, J Gatchalian, RC Stevens, ... Analytical chemistry 82 (3), 1100-1108, 2010 | 139 | 2010 |
| Structural mechanism for signal transduction in RXR nuclear receptor heterodimers DJ Kojetin, E Matta-Camacho, TS Hughes, S Srinivasan, JC Nwachukwu, ... Nature communications 6 (1), 8013, 2015 | 132 | 2015 |
| Identification of Mycobacterium tuberculosis H37Rv Integral Membrane Proteins by One-Dimensional Gel Electrophoresis and Liquid Chromatography … Y Xiong, MJ Chalmers, FP Gao, TA Cross, AG Marshall Journal of proteome research 4 (3), 855-861, 2005 | 127 | 2005 |
| HD desktop: an integrated platform for the analysis and visualization of H/D exchange data BD Pascal, MJ Chalmers, SA Busby, PR Griffin Journal of the American Society for Mass Spectrometry 20, 601-610, 2009 | 119 | 2009 |
| Combined top-down and bottom-up mass spectrometric approach to characterization of biomarkers for renal disease MJ Chalmers, CL Mackay, CL Hendrickson, S Wittke, M Walden, ... Analytical Chemistry 77 (22), 7163-7171, 2005 | 113 | 2005 |
| Hydrogen/deuterium exchange reveals distinct agonist/partial agonist receptor dynamics within vitamin D receptor/retinoid X receptor heterodimer J Zhang, MJ Chalmers, KR Stayrook, LL Burris, RD Garcia-Ordonez, ... Structure 18 (10), 1332-1341, 2010 | 112 | 2010 |
Patrick R GriffinProfessor of Molecular Medicine, UF Scripps Biomedical ResearchVerified email at scripps.edu
