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Pengxiang Chang
Pengxiang Chang
Senior Research Scientist
Verified email at sanofi.com
Title
Cited by
Cited by
Year
Dual recognition element lateral flow assay toward multiplex strain specific influenza virus detection
TT Le, P Chang, DJ Benton, JW McCauley, M Iqbal, AEG Cass
Analytical chemistry 89 (12), 6781-6786, 2017
1122017
A simple and rapid approach to develop recombinant avian herpesvirus vectored vaccines using CRISPR/Cas9 system
N Tang, Y Zhang, M Pedrera, P Chang, S Baigent, K Moffat, Z Shen, ...
Vaccine 36 (5), 716-722, 2018
732018
Variability in H9N2 haemagglutinin receptor-binding preference and the pH of fusion
TP Peacock, DJ Benton, JR Sadeyen, P Chang, JE Sealy, JE Bryant, ...
Emerging microbes & infections 6 (1), 1-7, 2017
472017
Structure–function analysis of neutralizing antibodies to H7N9 influenza from naturally infected humans
KYA Huang, P Rijal, H Jiang, B Wang, L Schimanski, T Dong, YM Liu, ...
Nature microbiology 4 (2), 306-315, 2019
432019
Immune Escape Variants of H9N2 Influenza Viruses Containing Deletions at the Hemagglutinin Receptor Binding Site Retain Fitness In Vivo and Display …
TP Peacock, DJ Benton, J James, JR Sadeyen, P Chang, JE Sealy, ...
Journal of virology 91 (14), 10.1128/jvi. 00218-17, 2017
422017
Association of increased receptor-binding avidity of influenza A (H9N2) viruses with escape from antibody-based immunity and enhanced zoonotic potential
JE Sealy, T Yaqub, TP Peacock, P Chang, B Ermetal, A Clements, ...
Emerging infectious diseases 25 (1), 63, 2019
402019
Mammalian innate resistance to highly pathogenic avian influenza H5N1 virus infection is mediated through reduced proinflammation and infectious virus release
RK Nelli, SP Dunham, SV Kuchipudi, GA White, B Baquero-Perez, ...
Journal of virology 86 (17), 9201-9210, 2012
402012
Immunogenicity and protective efficacy of an intranasal live-attenuated vaccine against SARS-CoV-2
JG Park, FS Oladunni, MA Rohaim, J Whittingham-Dowd, J Tollitt, ...
IScience 24 (9), 2021
372021
The application of NHEJ-CRISPR/Cas9 and Cre-Lox system in the generation of bivalent duck enteritis virus vaccine against avian influenza virus
P Chang, Y Yao, N Tang, JR Sadeyen, J Sealy, A Clements, S Bhat, ...
Viruses 10 (2), 81, 2018
342018
Early apoptosis of porcine alveolar macrophages limits avian influenza virus replication and pro-inflammatory dysregulation
P Chang, SV Kuchipudi, KH Mellits, S Sebastian, J James, J Liu, ...
Scientific reports 5 (1), 17999, 2015
322015
Immune escape adaptive mutations in the H7N9 avian influenza hemagglutinin protein increase virus replication fitness and decrease pandemic potential
P Chang, JE Sealy, JR Sadeyen, S Bhat, D Lukosaityte, Y Sun, M Iqbal
Journal of Virology 94 (19), 10.1128/jvi. 00216-20, 2020
312020
Application of HDR-CRISPR/Cas9 and erythrocyte binding for rapid generation of recombinant turkey herpesvirus-vectored avian influenza virus vaccines
P Chang, F Ameen, JE Sealy, JR Sadeyen, S Bhat, Y Li, M Iqbal
Vaccines 7 (4), 192, 2019
282019
Coinfection of chickens with H9N2 and H7N9 avian influenza viruses leads to emergence of reassortant H9N9 virus with increased fitness for poultry and a zoonotic potential
S Bhat, J James, JR Sadeyen, S Mahmood, HJ Everest, P Chang, ...
Journal of virology 96 (5), e01856-21, 2022
242022
Amino acid residue 217 in the hemagglutinin glycoprotein is a key mediator of avian influenza H7N9 virus antigenicity
P Chang, JE Sealy, JR Sadeyen, M Iqbal
Journal of Virology 93 (1), 10.1128/jvi. 01627-18, 2019
232019
Presence of antibodies to SARS-CoV-2 in domestic cats in Istanbul, Turkey, before and after COVID-19 pandemic
A Yilmaz, A Kayar, N Turan, O Iskefli, A Bayrakal, G Roman-Sosa, E Or, ...
Frontiers in veterinary science 8, 707368, 2021
182021
Generating recombinant avian herpesvirus vectors with crispr/cas9 gene editing
N Tang, Y Zhang, M Pedrera, P Chang, S Baigent, K Moffat, Z Shen, ...
JoVE (Journal of Visualized Experiments), e58193, 2019
172019
A ligation and restriction enzyme independent cloning technique: an alternative to conventional methods for cloning hard-to-clone gene segments in the influenza reverse …
S Bhat, D Bialy, JE Sealy, JR Sadeyen, P Chang, M Iqbal
Virology journal 17, 1-9, 2020
142020
Cadmium triggers oxidative stress and mitochondrial injury mediated apoptosis in human extravillous trophoblast HTR-8/SVneo cells
F Dong, P Xiao, X Li, P Chang, W Zhang, L Wang
Reproductive Toxicology 101, 18-27, 2021
122021
Engineered recombinant single chain variable fragment of monoclonal antibody provides protection to chickens infected with H9N2 avian influenza
D Lukosaityte, JR Sadeyen, A Shrestha, JE Sealy, S Bhat, P Chang, ...
Vaccines 8 (1), 118, 2020
122020
Adsorptive mutation and N-linked glycosylation modulate influenza virus antigenicity and fitness
JE Sealy, TP Peacock, JR Sadeyen, P Chang, HJ Everest, S Bhat, M Iqbal
Emerging Microbes & Infections 9 (1), 2622-2631, 2020
112020
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