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Emily S.J.  Edwards
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Rapid generation of durable B cell memory to SARS-CoV-2 spike and nucleocapsid proteins in COVID-19 and convalescence
GE Hartley, ESJ Edwards, PM Aui, N Varese, S Stojanovic, J McMahon, ...
Science immunology 5 (54), eabf8891, 2020
3082020
Human immunity against EBV—lessons from the clinic
SG Tangye, U Palendira, ESJ Edwards
Journal of Experimental Medicine 214 (2), 269-283, 2017
1922017
Protein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramers
A Lissina, K Ladell, A Skowera, M Clement, E Edwards, R Seggewiss, ...
Journal of immunological methods 340 (1), 11-24, 2009
1892009
Combined immunodeficiency and Epstein-Barr virus–induced B cell malignancy in humans with inherited CD70 deficiency
H Abolhassani, ESJ Edwards, A Ikinciogullari, H Jing, S Borte, M Buggert, ...
Journal of Experimental Medicine 214 (1), 91-106, 2017
1632017
Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognition
DK Cole, ESJ Edwards, KK Wynn, M Clement, JJ Miles, K Ladell, ...
The Journal of Immunology 185 (4), 2600-2610, 2010
1622010
Activating PIK3CD mutations impair human cytotoxic lymphocyte differentiation and function and EBV immunity
ESJ Edwards, J Bier, TS Cole, M Wong, P Hsu, LJ Berglund, K Boztug, ...
Journal of Allergy and Clinical Immunology 143 (1), 276-291. e6, 2019
922019
Extended clinical and immunological phenotype and transplant outcome in CD27 and CD70 deficiency
S Ghosh, S Köstel Bal, ESJ Edwards, B Pillay, R Jiménez Heredia, ...
Blood, The Journal of the American Society of Hematology 136 (23), 2638-2655, 2020
902020
T-cell receptor-optimized peptide skewing of the T-cell repertoire can enhance antigen targeting
J Ekeruche-Makinde, M Clement, DK Cole, ESJ Edwards, K Ladell, ...
Journal of Biological Chemistry 287 (44), 37269-37281, 2012
722012
Activating mutations in PIK3CD disrupt the differentiation and function of human and murine CD4+ T cells
J Bier, G Rao, K Payne, H Brigden, E French, SJ Pelham, A Lau, ...
Journal of Allergy and Clinical Immunology 144 (1), 236-253, 2019
642019
Anti-CD8 antibodies can trigger CD8+ T cell effector function in the absence of TCR engagement and improve peptide–MHCI tetramer staining
M Clement, K Ladell, J Ekeruche-Makinde, JJ Miles, ESJ Edwards, ...
The Journal of Immunology 187 (2), 654-663, 2011
592011
Predominantly antibody-deficient patients with non-infectious complications have reduced naive B, Treg, Th17, and Tfh17 cells
ESJ Edwards, JJ Bosco, PM Aui, RG Stirling, PU Cameron, J Chatelier, ...
Frontiers in Immunology 10, 2593, 2019
552019
MHC class I molecules with superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs
L Wooldridge, M Clement, A Lissina, ESJ Edwards, K Ladell, J Ekeruche, ...
The Journal of Immunology 184 (7), 3357-3366, 2010
392010
Diversity of XMEN disease: description of 2 novel variants and analysis of the lymphocyte phenotype
EM Klinken, PE Gray, B Pillay, L Worley, ESJ Edwards, K Payne, ...
Journal of Clinical Immunology 40, 299-309, 2020
332020
Beyond monogenetic rare variants: tackling the low rate of genetic diagnoses in predominantly antibody deficiency
ESJ Edwards, JJ Bosco, S Ojaimi, RE O’Hehir, MC van Zelm
Cellular & Molecular Immunology 18 (3), 588-603, 2021
322021
Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry
JJ Miles, MP Tan, G Dolton, ESJ Edwards, SAE Galloway, B Laugel, ...
The Journal of clinical investigation 128 (4), 1569-1580, 2018
312018
Influenza‐specific IgG1+ memory B‐cell numbers increase upon booster vaccination in healthy adults but not in patients with predominantly antibody deficiency
GE Hartley, ESJ Edwards, JJ Bosco, S Ojaimi, RG Stirling, PU Cameron, ...
Clinical & Translational Immunology 9 (10), e1199, 2020
182020
The Rapidly Expanding Genetic Spectrum of Common Variable Immunodeficiency–Like Disorders
R Ameratunga, ESJ Edwards, K Lehnert, E Leung, ST Woon, E Lea, ...
The Journal of Allergy and Clinical Immunology: In Practice 11 (6), 1646-1664, 2023
152023
Phenotypic and transcriptional profile correlates with functional plasticity of antigen‐specific CD4+ T cells
ESJ Edwards, C Smith, R Khanna
Immunology and cell biology 92 (2), 181-190, 2014
132014
COVID-19 adenoviral vector vaccination elicits a robust memory B cell response with the capacity to recognize omicron BA. 2 and BA. 5 variants
HA Fryer, GE Hartley, ESJ Edwards, N Varese, I Boo, SJ Bornheimer, ...
Journal of Clinical Immunology 43 (7), 1506-1518, 2023
122023
Common variable immunodeficiency disorders as a model for assessing COVID-19 vaccine responses in immunocompromised patients
R Ameratunga, ST Woon, R Steele, K Lehnert, E Leung, ESJ Edwards, ...
Frontiers in Immunology 12, 798389, 2022
122022
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Articles 1–20