Caitlin Connelly
Caitlin Connelly
Calico Life Sciences
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Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden
ZR Chalmers, CF Connelly, D Fabrizio, L Gay, SM Ali, R Ennis, A Schrock, ...
Genome medicine 9, 1-14, 2017
Tracking footprints of artificial selection in the dog genome
JM Akey, AL Ruhe, DT Akey, AK Wong, CF Connelly, J Madeoy, ...
Proceedings of the National Academy of Sciences 107 (3), 1160-1165, 2010
Prevalence of PDL1 amplification and preliminary response to immune checkpoint blockade in solid tumors
AM Goodman, D Piccioni, S Kato, A Boichard, HY Wang, G Frampton, ...
JAMA oncology 4 (9), 1237-1244, 2018
Comprehensive characterization of RAS mutations in colon and rectal cancers in old and young patients
IG Serebriiskii, C Connelly, G Frampton, J Newberg, M Cooke, V Miller, ...
Nature communications 10 (1), 3722, 2019
Integrative phenomics reveals insight into the structure of phenotypic diversity in budding yeast
DA Skelly, GE Merrihew, M Riffle, CF Connelly, EO Kerr, M Johansson, ...
Genome research 23 (9), 1496-1504, 2013
Comprehensive genomic landscapes in early and later onset colorectal cancer
CH Lieu, EA Golemis, IG Serebriiskii, J Newberg, A Hemmerich, ...
Clinical Cancer Research 25 (19), 5852-5858, 2019
An ortholog of MIXTA‐like2 controls epidermal cell shape in flowers of Thalictrum
VS Di Stilio, C Martin, AF Schulfer, CF Connelly
New Phytologist 183 (3), 718-728, 2009
Detection of clonal hematopoiesis of indeterminate potential in clinical sequencing of solid tumor specimens
EA Severson, GM Riedlinger, CF Connelly, JA Vergilio, M Goldfinger, ...
Blood, The Journal of the American Society of Hematology 131 (22), 2501-2505, 2018
Protein kinase R and the integrated stress response drive immunopathology caused by mutations in the RNA deaminase ADAR1
M Maurano, JM Snyder, C Connelly, J Henao-Mejia, C Sidrauski, ...
Immunity 54 (9), 1948-1960. e5, 2021
On the prospects of whole-genome association mapping in Saccharomyces cerevisiae
CF Connelly, JM Akey
Genetics 191 (4), 1345-1353, 2012
Population Genomic Analysis of ALMS1 in Humans Reveals a Surprisingly Complex Evolutionary History
LB Scheinfeldt, S Biswas, J Madeoy, CF Connelly, EE Schadt, JM Akey
Molecular biology and evolution 26 (6), 1357-1367, 2009
Highly punctuated patterns of population structure on the X chromosome and implications for African evolutionary history
CA Lambert, CF Connelly, J Madeoy, R Qiu, MV Olson, JM Akey
The American Journal of Human Genetics 86 (1), 34-44, 2010
Evolution and genetic architecture of chromatin accessibility and function in yeast
CF Connelly, J Wakefield, JM Akey
PLoS genetics 10 (7), e1004427, 2014
Population genomics of intron splicing in 38 Saccharomyces cerevisiae genome sequences
DA Skelly, J Ronald, CF Connelly, JM Akey
Genome biology and evolution 1, 466-478, 2009
MA14. 01 Updated dataset assessing tumor mutation burden (TMB) as a biomarker for response to PD-1/PD-L1 targeted therapies in lung cancer (LC)
A Schrock, N Sharma, N Peled, J Bufill, G Srkalovic, D Spigel, D Fabrizio, ...
Journal of Thoracic Oncology 12 (1), S422, 2017
A synthetic biology approach to probing nucleosome symmetry
Y Ichikawa, CF Connelly, A Appleboim, TCR Miller, H Jacobi, NA Abshiru, ...
Elife 6, e28836, 2017
Determining patient ancestry based on targeted tumor comprehensive genomic profiling
J Newberg, C Connelly, G Frampton
Cancer Research 79 (13_Supplement), 1599-1599, 2019
Methods and systems for evaluating tumor mutational burden
ZR Chalmers, CF Connelly, D Fabrizio, GM Frampton, P Hegde, ...
US Patent App. 16/115,373, 2018
Somatic genome alterations in cancer as compared to inferred patient ancestry
CF Connelly, J Carrot-Zhang, PJ Stephens, GM Frampton
Cancer Research 78 (13 Supplement), 1227-1227, 2018
Population Genomics and Transcriptional Consequences of Regulatory Motif Variation in Globally Diverse Saccharomyces cerevisiae Strains
CF Connelly, DA Skelly, MJ Dunham, JM Akey
Molecular biology and evolution 30 (7), 1605-1613, 2013
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