Följ
John T. Cunningham
John T. Cunningham
Department of Cancer Biology, University of Cincinnati College of Medicine
Verifierad e-postadress på ucmail.uc.edu
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mTOR controls mitochondrial oxidative function through a YY1–PGC-1α transcriptional complex
JT Cunningham, JT Rodgers, DH Arlow, F Vazquez, VK Mootha, ...
nature 450 (7170), 736-740, 2007
16442007
ER stress–mediated autophagy promotes Myc-dependent transformation and tumor growth
LS Hart, JT Cunningham, T Datta, S Dey, F Tameire, SL Lehman, BO Qiu, ...
The Journal of clinical investigation 122 (12), 4621-4634, 2012
4262012
Protein and nucleotide biosynthesis are coupled by a single rate-limiting enzyme, PRPS2, to drive cancer
JT Cunningham, MV Moreno, A Lodi, SM Ronen, D Ruggero
Cell 157 (5), 1088-1103, 2014
2342014
Translation control of the immune checkpoint in cancer and its therapeutic targeting
Y Xu, M Poggio, HY Jin, Z Shi, CM Forester, Y Wang, CR Stumpf, L Xue, ...
Nature medicine 25 (2), 301-311, 2019
2102019
Development of a stress response therapy targeting aggressive prostate cancer
HG Nguyen, CS Conn, Y Kye, L Xue, CM Forester, JE Cowan, AC Hsieh, ...
Science translational medicine 10 (439), eaar2036, 2018
1462018
Yin Yang 1 deficiency in skeletal muscle protects against rapamycin-induced diabetic-like symptoms through activation of insulin/IGF signaling
SM Blättler, JT Cunningham, F Verdeguer, H Chim, W Haas, H Liu, ...
Cell metabolism 15 (4), 505-517, 2012
1052012
Defective mitochondrial morphology and bioenergetic function in mice lacking the transcription factor Yin Yang 1 in skeletal muscle
SM Blättler, F Verdeguer, M Liesa, JT Cunningham, RO Vogel, H Chim, ...
Molecular and cellular biology 32 (16), 3333-3346, 2012
922012
Noninvasive Measurement of mTORC1 Signaling with 89Zr-Transferrin
C Truillet, JT Cunningham, MFL Parker, LT Huynh, CS Conn, D Ruggero, ...
Clinical Cancer Research 23 (12), 3045-3052, 2017
262017
POPULATION GENETICS OF RESURGENCE: WHITE-TAILED DEER IN KENTUCKY
KC Doerner, W Braden, J Cork, T Cunningham, A Rice, BJ Furman, ...
Journal of Wildlife Management 69 (1), 345-355, 2005
262005
Tobacco smoking induces metabolic reprogramming of renal cell carcinoma
J Reigle, D Secic, J Biesiada, C Wetzel, B Shamsaei, J Chu, Y Zang, ...
The Journal of clinical investigation 131 (1), 2021
182021
New connections between old pathways: PDK1 signaling promotes cellular transformation through PLK1-dependent MYC stabilization
JT Cunningham, D Ruggero
Cancer discovery 3 (10), 1099-1102, 2013
182013
Molecular and metabolic subtypes in sporadic and inherited clear cell renal cell carcinoma
MF Czyzyk-Krzeska, JA Landero Figueroa, S Gulati, JT Cunningham, ...
Genes 12 (3), 388, 2021
122021
Decreased genetic dosage of hepatic Yin Yang 1 causes diabetic-like symptoms
F Verdeguer, SM Blättler, JT Cunningham, JA Hall, H Chim, P Puigserver
Molecular Endocrinology 28 (3), 308-316, 2014
122014
Investigating Myc-dependent translational regulation in normal and cancer cells
JT Cunningham, M Pourdehnad, CR Stumpf, D Ruggero
The Myc Gene: Methods and Protocols, 201-212, 2013
102013
Complimentary transcriptomic-metallomic analysis identifies risk of relapse for clear-cell renal cell carcinoma (ccRCC) patients.
S Gulati, B Vemuri, D Secic, B Shamsaei, DR Plas, JT Cunningham, ...
Journal of Clinical Oncology 40 (6_suppl), 378-378, 2022
2022
Metabolic subtypes of clear cell renal cell carcinoma defined by tobacco smoking
MF Czyzyk-Krzeska, J Meller, JA Landero Figueroa, DR Plas, ...
Molecular & Cellular Oncology 8 (2), 1859917, 2021
2021
Molecular and Metabolic Subtypes in Sporadic and Inherited Clear Cell Renal Cell Carcinoma. Genes 2021, 12, 388
MF Czyzyk-Krzeska, JA Landero Figueroa, S Gulati, JT Cunningham, ...
s Note: MDPI stays neutral with regard to jurisdictional claims in published …, 2021
2021
Phosphoribosyl pyrophosphate synthetase 2 (PRPS2) as a therapeutic target in cancer treatment
D Ruggero, JT Cunningham
US Patent 9,765,337, 2017
2017
Abstract A25: Sensing stress in cancer: a novel therapy targeting protein synthesis through the unfolded protein response in prostate cancer development
CS Conn, HG Nguyen, Y Kye, JT Cunningham, C Truillet, M Evans, ...
Cancer Research 77 (6_Supplement), A25-A25, 2017
2017
Sensing stress in cancer: a novel therapy targeting protein synthesis through the unfolded protein response in prostate cancer development
CS Conn, HG Nguyen, Y Kye, JT Cunningham, C Truillet, M Evans, ...
CANCER RESEARCH 77, 2017
2017
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Artiklar 1–20