| Frizzled proteins are colonic epithelial receptors for C. difficile toxin B L Tao, J Zhang, P Meraner, A Tovaglieri, X Wu, R Gerhard, X Zhang, ... Nature 538 (7625), 350-355, 2016 | 278 | 2016 |
| Synthesis, structure–activity relationship studies, and antibacterial evaluation of 4-chromanones and chalcones, as well as olympicin A and derivatives L Feng, MM Maddox, MZ Alam, LS Tsutsumi, G Narula, DF Bruhn, X Wu, ... Journal of medicinal chemistry 57 (20), 8398-8420, 2014 | 110 | 2014 |
| Alternative Sigma Factor σH Modulates Prophage Integration and Excision in Staphylococcus aureus L Tao, X Wu, B Sun PLoS pathogens 6 (5), e1000888, 2010 | 58 | 2010 |
| Sulfhydryl compounds reduce Staphylococcus aureus biofilm formation by inhibiting PIA biosynthesis X Wu, Y Wang, L Tao FEMS microbiology letters 316 (1), 44-50, 2011 | 51 | 2011 |
| Mode of action and bactericidal properties of surotomycin against growing and nongrowing Clostridium difficile MZ Alam, X Wu, C Mascio, L Chesnel, JG Hurdle Antimicrobial agents and chemotherapy 59 (9), 5165-5170, 2015 | 44 | 2015 |
| The membrane as a target for controlling hypervirulent Clostridium difficile infections X Wu, PT Cherian, RE Lee, JG Hurdle Journal of Antimicrobial Chemotherapy 68 (4), 806-815, 2013 | 43 | 2013 |
| Gastrointestinal localization of metronidazole by a lactobacilli-inspired tetramic acid motif improves treatment outcomes in the hamster model of Clostridium difficile infection PT Cherian, X Wu, L Yang, JS Scarborough, AP Singh, ZA Alam, RE Lee, ... Journal of Antimicrobial Chemotherapy 70 (11), 3061-3069, 2015 | 41 | 2015 |
| A selective antibiotic for Lyme disease N Leimer, X Wu, Y Imai, M Morrissette, N Pitt, Q Favre-Godal, A Iinishi, ... Cell 184 (21), 5405-5418. e16, 2021 | 40 | 2021 |
| Chromosomal resistance to metronidazole in Clostridioides difficile can be mediated by epistasis between iron homeostasis and oxidoreductases A Deshpande, X Wu, W Huo, KL Palmer, JG Hurdle Antimicrobial agents and chemotherapy 64 (8), 10.1128/aac. 00415-20, 2020 | 36 | 2020 |
| Chemical Modulation of the Biological Activity of Reutericyclin: a Membrane-Active Antibiotic from Lactobacillusreuteri PT Cherian, X Wu, MM Maddox, AP Singh, RE Lee, JG Hurdle Scientific reports 4 (1), 4721, 2014 | 36 | 2014 |
| The Fatty Acid Synthesis Protein Enoyl-ACP Reductase II (FabK) is a Target for Narrow-Spectrum Antibacterials for Clostridium difficile Infection RKR Marreddy, X Wu, M Sapkota, AM Prior, JA Jones, D Sun, ... ACS infectious diseases 5 (2), 208-217, 2018 | 34 | 2018 |
| Rifamycin resistance in Clostridium difficile is generally associated with a low fitness burden UT Dang, I Zamora, KE Hevener, S Adhikari, X Wu, JG Hurdle Antimicrobial Agents and Chemotherapy 60 (9), 5604-5607, 2016 | 27 | 2016 |
| Prospects for flavonoid and related phytochemicals as nature‐inspired treatments for Clostridium difficile infection X Wu, MZ Alam, L Feng, LS Tsutsumi, D Sun, JG Hurdle Journal of applied microbiology 116 (1), 23-31, 2014 | 24 | 2014 |
| Identifying vancomycin as an effective antibiotic for killing Borrelia burgdorferi X Wu, B Sharma, S Niles, K O'Connor, R Schilling, N Matluck, A D'Onofrio, ... Antimicrobial agents and chemotherapy 62 (11), 10.1128/aac. 01201-18, 2018 | 22 | 2018 |
| The integrity of heme is essential for reproducible detection of metronidazole-resistant Clostridioides difficile by agar dilution susceptibility tests X Wu, WJ Shen, A Deshpande, AO Olaitan, KL Palmer, KW Garey, ... Journal of Clinical Microbiology 59 (9), 10.1128/jcm. 00585-21, 2021 | 21 | 2021 |
| The Clostridium difficile proline racemase is not essential for early logarithmic growth and infection X Wu, JG Hurdle Canadian journal of microbiology 60 (4), 251-254, 2014 | 18 | 2014 |
| Frizzled are colonic epithelial receptors for Clostridium difficile toxin B L Tao, J Zhang, P Meraner, A Tovaglieri, X Wu, R Gerhard, X Zhang, ... Nature 538 (7625), 350, 2016 | 9 | 2016 |
| The early stage peptidoglycan biosynthesis Mur enzymes are antibacterial and antisporulation drug targets for recurrent Clostridioides difficile infection M Sapkota, RKR Marreddy, X Wu, M Kumar, JG Hurdle Anaerobe 61, 102129, 2020 | 7 | 2020 |
| A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections MAT Blaskovich, KA Hansford, MS Butler, S Ramu, AM Kavanagh, ... Science translational medicine 14 (662), eabj2381, 2022 | 6 | 2022 |
| Screening for a Diamond in the Rough X Wu, JG Hurdle Chemistry & biology 20 (9), 1091-1092, 2013 | 5 | 2013 |
