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Jacob L Litke
Jacob L Litke
Weill Cornell Medicine
Verifierad e-postadress på med.cornell.edu
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Highly efficient expression of circular RNA aptamers in cells using autocatalytic transcripts
JL Litke, SR Jaffrey
Nature biotechnology 37 (6), 667-675, 2019
2182019
Imaging metabolite dynamics in living cells using a Spinach-based riboswitch
M You, JL Litke, SR Jaffrey
Proceedings of the National Academy of Sciences 112 (21), E2756-E2765, 2015
2032015
Fluorophore‐promoted RNA folding and photostability enables imaging of single broccoli‐tagged mRNAs in live mammalian cells
X Li, H Kim, JL Litke, J Wu, SR Jaffrey
Angewandte Chemie International Edition 59 (11), 4511-4518, 2020
712020
Imaging Intracellular S-Adenosyl Methionine Dynamics in Live Mammalian Cells with a Genetically Encoded Red Fluorescent RNA-Based Sensor
X Li, L Mo, JL Litke, SK Dey, SR Suter, SR Jaffrey
Journal of the American Chemical Society 142 (33), 14117-14124, 2020
552020
Detection of low-abundance metabolites in live cells using an RNA integrator
M You, JL Litke, R Wu, SR Jaffrey
Cell chemical biology 26 (4), 471-481. e3, 2019
402019
Developing fluorogenic riboswitches for imaging metabolite concentration dynamics in bacterial cells
JL Litke, M You, SR Jaffrey
Methods in enzymology 572, 315-333, 2016
272016
Naturally occurring three-way junctions can be repurposed as genetically encoded RNA-based sensors
JD Moon, J Wu, SK Dey, JL Litke, X Li, H Kim, SR Jaffrey
Cell chemical biology 28 (11), 1569-1580. e4, 2021
122021
Probing the ion binding site in a DNA Holliday junction using Förster resonance energy transfer (FRET)
JL Litke, Y Li, LM Nocka, I Mukerji
International journal of molecular sciences 17 (3), 366, 2016
112016
Trans ligation of RNAs to generate hybrid circular RNAs using highly efficient autocatalytic transcripts
JL Litke, SR Jaffrey
Methods 196, 104-112, 2021
102021
Designing and expressing circular RNA aptamers to regulate mammalian cell biology
JL Litke, SR Jaffrey
Nucleic Acid Aptamers: Selection, Characterization, and Application, 223-234, 2022
22022
Rna molecules, methods of producing circular rna, and treatment methods
SR Jaffrey, JL Litke
US Patent App. 18/355,546, 2024
2024
RNA molecules, methods of producing circular RNA, and treatment methods
SR Jaffrey, JL Litke
US Patent 11,756,183, 2023
2023
A Ribozyme-Mediated Mammalian Expression System and Its Utility for RNA-Based Devices and Aptamers in Live Cells
JL Litke
Weill Medical College of Cornell University, 2019
2019
Structure of DNA Four-Way Junctions: Effect of Ions and Proteins
I Mukerji, CI Vitoc, J Litke, E Wheatley, O Buzovetsky, Y Li, DL Beveridge
Biophysical Journal 102 (3), 75a, 2012
2012
Probing the Ion-Binding Site of the Holliday Junction
J Litke, I Mukerji
Biophysical Journal 100 (3), 322a, 2011
2011
Probing the Ion-Binding Site of the Holliday Junction: A Spectroscopic and Calorimetric Approach
JL Litke
2011
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Artiklar 1–16