Christophe Guignabert
Christophe Guignabert
Director of Research, INSERM, Université Paris-Saclay
Verifierad e-postadress på inserm.fr - Startsida
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Pulmonary arterial hypertension in patients treated by dasatinib
D Montani, E Bergot, S Günther, L Savale, A Bergeron, A Bourdin, ...
Circulation 125 (17), 2128-2137, 2012
5602012
Inflammation and immunity in the pathogenesis of pulmonary arterial hypertension
M Rabinovitch, C Guignabert, M Humbert, MR Nicolls
Circulation research 115 (1), 165-175, 2014
4632014
Relevant issues in the pathology and pathobiology of pulmonary hypertension
RM Tuder, SL Archer, P Dorfmüller, SC Erzurum, C Guignabert, ...
Journal of the American College of Cardiology 62 (25 Supplement), D4-D12, 2013
4552013
An antiproliferative BMP-2/PPARγ/apoE axis in human and murine SMCs and its role in pulmonary hypertension
G Hansmann, VA de Jesus Perez, TP Alastalo, CM Alvira, C Guignabert, ...
The Journal of clinical investigation 118 (5), 1846-1857, 2008
3362008
CLINICAL PERSPECTIVE
S Eddahibi, C Guignabert, AM Barlier-Mur, L Dewachter, E Fadel, ...
Circulation 113 (15), 1857-1864, 2006
3172006
Serotonin transporter inhibition prevents and reverses monocrotaline-induced pulmonary hypertension in rats
C Guignabert, B Raffestin, R Benferhat, W Raoul, P Zadigue, D Rideau, ...
Circulation 111 (21), 2812-2819, 2005
2552005
Pulmonary arterial remodeling induced by a Th2 immune response
E Daley, C Emson, C Guignabert, R de Waal Malefyt, J Louten, VP Kurup, ...
The Journal of experimental medicine 205 (2), 361-372, 2008
2482008
Right ventricular diastolic impairment in patients with pulmonary arterial hypertension
S Rain, ML Handoko, P Trip, CTJ Gan, N Westerhof, GJ Stienen, ...
Circulation 128 (18), 2016-2025, 2013
2472013
Dysregulated renin–angiotensin–aldosterone system contributes to pulmonary arterial hypertension
FS de Man, L Tu, ML Handoko, S Rain, G Ruiter, C François, I Schalij, ...
American journal of respiratory and critical care medicine 186 (8), 780-789, 2012
2462012
Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives
M Humbert, C Guignabert, S Bonnet, P Dorfmüller, JR Klinger, MR Nicolls, ...
European Respiratory Journal 53 (1), 2019
2052019
Transgenic mice overexpressing the 5-hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension
C Guignabert, M Izikki, LI Tu, Z Li, P Zadigue, AM Barlier-Mur, N Hanoun, ...
Circulation research 98 (10), 1323-1330, 2006
2012006
Endothelial-derived FGF2 contributes to the progression of pulmonary hypertension in humans and rodents
M Izikki, C Guignabert, E Fadel, M Humbert, L Tu, P Zadigue, P Dartevelle, ...
The Journal of clinical investigation 119 (3), 512-523, 2009
1982009
RhoA and Rho kinase activation in human pulmonary hypertension: role of 5-HT signaling
C Guilluy, S Eddahibi, C Agard, C Guignabert, M Izikki, L Tu, L Savale, ...
American journal of respiratory and critical care medicine 179 (12), 1151-1158, 2009
1712009
Targeted therapies in pulmonary arterial hypertension
D Montani, MC Chaumais, C Guignabert, S Günther, B Girerd, X Jaïs, ...
Pharmacology & therapeutics 141 (2), 172-191, 2014
1492014
Tie2-mediated loss of peroxisome proliferator-activated receptor-γ in mice causes PDGF receptor-β-dependent pulmonary arterial muscularization
C Guignabert, CM Alvira, TP Alastalo, H Sawada, G Hansmann, M Zhao, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 297 (6 …, 2009
1402009
Dasatinib induces lung vascular toxicity and predisposes to pulmonary hypertension
C Guignabert, C Phan, A Seferian, A Huertas, L Tu, R Thuillet, C Sattler, ...
The Journal of clinical investigation 126 (9), 3207-3218, 2016
1372016
Pathogenesis of pulmonary arterial hypertension: lessons from cancer
C Guignabert, L Tu, M Le Hiress, N Ricard, C Sattler, A Seferian, ...
European Respiratory Review 22 (130), 543-551, 2013
1332013
Increased Pericyte coverage mediated by endothelial-derived fibroblast growth Factor-2 and Interleukin-6 is a source of smooth muscle–like cells in pulmonary hypertension
N Ricard, L Tu, M Le Hiress, A Huertas, C Phan, R Thuillet, C Sattler, ...
Circulation 129 (15), 1586-1597, 2014
1302014
Autocrine fibroblast growth factor-2 signaling contributes to altered endothelial phenotype in pulmonary hypertension
L Tu, L Dewachter, B Gore, E Fadel, P Dartevelle, G Simonneau, ...
American journal of respiratory cell and molecular biology 45 (2), 311-322, 2011
1242011
New molecular targets of pulmonary vascular remodeling in pulmonary arterial hypertension: importance of endothelial communication
C Guignabert, L Tu, B Girerd, N Ricard, A Huertas, D Montani, M Humbert
Chest 147 (2), 529-537, 2015
1152015
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