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Phillip T Newton
Phillip T Newton
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
107352021
A radical switch in clonality reveals a stem cell niche in the epiphyseal growth plate
PT Newton, L Li, B Zhou, C Schweingruber, M Hovorakova, M Xie, X Sun, ...
Nature 567 (7747), 234-238, 2019
1742019
Targeted deletion of Atg5 in chondrocytes promotes age-related osteoarthritis
T Bouderlique, KK Vuppalapati, PT Newton, L Li, B Barenius, AS Chagin
Annals of the rheumatic diseases 75 (3), 627-631, 2016
1252016
Superficial cells are self-renewing chondrocyte progenitors, which form the articular cartilage in juvenile mice
L Li, PT Newton, T Bouderlique, M Sejnohova, T Zikmund, ...
The FASEB Journal 31 (3), 1067-1084, 2016
1102016
Chondrogenic ATDC5 cells: An optimised model for rapid and physiological matrix mineralisation
PT Newton, KA Staines, L Spevak, AL Boskey, CC Teixeira, VE Macrae, ...
International journal of molecular medicine 30 (5), 1187-1193, 2012
952012
Targeted Deletion of Autophagy Genes Atg5 or Atg7 in the Chondrocytes Promotes Caspase‐Dependent Cell Death and Leads to Mild Growth Retardation
KK Vuppalapati, T Bouderlique, PT Newton, VO Kaminskyy, H Wehtje, ...
Journal of Bone and Mineral Research 30 (12), 2249-2261, 2015
882015
Maresin 1 attenuates neuroinflammation in a mouse model of perioperative neurocognitive disorders
T Yang, G Xu, PT Newton, AS Chagin, S Mkrtchian, M Carlström, ...
British journal of anaesthesia 122 (3), 350-360, 2019
862019
Stimulation of the α7 nicotinic acetylcholine receptor protects against neuroinflammation after tibia fracture and endotoxemia in mice.
N Terrando, T Yang, JK Ryu, PT Newton, C Monaco, M Feldmann, D Ma, ...
Molecular Medicine 21 (2), 2014
852014
Niches for skeletal stem cells of mesenchymal origin
AD Kurenkova, EV Medvedeva, PT Newton, AS Chagin
Frontiers in cell and developmental biology 8, 592, 2020
582020
Oriented clonal cell dynamics enables accurate growth and shaping of vertebrate cartilage
M Kaucka, T Zikmund, M Tesarova, D Gyllborg, A Hellander, J Jaros, ...
eLife 6, e25902, 2017
582017
Pharmacological inhibition of lysosomes activates the MTORC1 signaling pathway in chondrocytes in an autophagy-independent manner
PT Newton, KK Vuppalapati, T Bouderlique, AS Chagin
Autophagy 11 (9), 1594-1607, 2015
512015
Absence of GP130 cytokine receptor signaling causes extended Stüve-Wiedemann syndrome
YH Chen, G Grigelioniene, PT Newton, J Gullander, M Elfving, ...
Journal of Experimental Medicine 217 (3), 2020
492020
Dietary nitrate attenuates high-fat diet-induced obesity via mechanisms involving higher adipocyte respiration and alterations in inflammatory status
M Peleli, DMS Ferreira, L Tarnawski, SMC Haworth, L Xuechen, Z Zhuge, ...
Redox biology 28, 101387, 2020
412020
Postnatal skeletal growth is driven by the epiphyseal stem cell niche
AS Chagin, PT Newton, AS Chagin
Endocrinology 143, 1851-7, 2020
35*2020
Secondary ossification center induces and protects growth plate structure
M Xie, P Gol'Din, AN Herdina, J Estefa, EV Medvedeva, L Li, PT Newton, ...
Elife 9, e55212, 2020
342020
Novel KIAA0753 mutations extend the phenotype of skeletal ciliopathies
A Hammarsjö, Z Wang, R Vaz, F Taylan, M Sedghi, KM Girisha, ...
Scientific reports 7 (1), 1-13, 2017
302017
Activation of mTORC1 in chondrocytes does not affect proliferation or differentiation, but causes the resting zone of the growth plate to become disordered
PT Newton, M Xie, EV Medvedeva, L Sävendahl, AS Chagin
Bone Reports 8, 64-71, 2018
242018
Expression of Sulf1 and Sulf2 in cartilage, bone and endochondral fracture healing
G Zaman, KA Staines, C Farquharson, PT Newton, J Dudhia, C Chenu, ...
Histochemistry and cell biology 145 (1), 67-79, 2016
242016
New insights into niclosamide action: autophagy activation in colorectal cancer
PT Newton
Biochemical Journal 476 (5), 779-781, 2019
212019
Spatially resolved transcriptomic profiling of degraded and challenging fresh frozen samples
R Mirzazadeh, Z Andrusivova, L Larsson, P Newton, LA Galicia, XM Abalo, ...
bioRxiv, 2022
142022
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Artiklar 1–20