Biological insights from 108 schizophrenia-associated genetic loci C Pantelis, GN Papadimitriou, S Papiol, E Parkhomenko, MT Pato, ... Nature 511 (7510), 421-427, 2014 | 7330 | 2014 |
Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model Y Yoshiyama, M Higuchi, B Zhang, SM Huang, N Iwata, TC Saido, ... Neuron 53 (3), 337-351, 2007 | 2102 | 2007 |
Age-dependent changes in brain, CSF, and plasma amyloid β protein in the Tg2576 transgenic mouse model of Alzheimer's disease T Kawarabayashi, LH Younkin, TC Saido, M Shoji, KH Ashe, SG Younkin Journal of neuroscience 21 (2), 372-381, 2001 | 1278 | 2001 |
Metabolic regulation of brain Aβ by neprilysin N Iwata, S Tsubuki, Y Takaki, K Shirotani, B Lu, NP Gerard, C Gerard, ... Science 292 (5521), 1550-1552, 2001 | 1260 | 2001 |
Identification of the major Aβ1–42-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition N Iwata, S Tsubuki, Y Takaki, K Watanabe, M Sekiguchi, E Hosoki, ... Nature medicine 6 (2), 143-150, 2000 | 1119 | 2000 |
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Calpain: new perspectives in molecular diversity and physiological‐pathological involvement TC Saido, H Sorimachi, K Suzuki The FASEB Journal 8 (11), 814-822, 1994 | 872 | 1994 |
Imaging of tau pathology in a tauopathy mouse model and in Alzheimer patients compared to normal controls M Maruyama, H Shimada, T Suhara, H Shinotoh, B Ji, J Maeda, ... Neuron 79 (6), 1094-1108, 2013 | 828 | 2013 |
Microglial response to amyloid plaques in APPsw transgenic mice. SA Frautschy, F Yang, M Irrizarry, B Hyman, TC Saido, K Hsiao, GM Cole The American journal of pathology 152 (1), 307, 1998 | 800 | 1998 |
Sequence of deposition of heterogeneous amyloid β-peptides and APO E in Down syndrome: implications for initial events in amyloid plaque formation CA Lemere, JK Blusztajn, H Yamaguchi, T Wisniewski, TC Saido, ... Neurobiology of disease 3 (1), 16-32, 1996 | 741 | 1996 |
Dominant and differential deposition of distinct β-amyloid peptide species, AβN3 (pE), in senile plaques TC Saido, T Iwatsubo, DMA Mann, H Shimada, Y Ihara, S Kawashima Neuron 14 (2), 457-466, 1995 | 725 | 1995 |
APP mouse models for Alzheimer's disease preclinical studies H Sasaguri, P Nilsson, S Hashimoto, K Nagata, T Saito, B De Strooper, ... The EMBO journal 36 (17), 2473-2487, 2017 | 698 | 2017 |
Proteolysis of Fodrin (Non-erythroid Spectrin) during Apoptosis (∗) SJ Martin, GA O'Brien, WK Nishioka, AJ McGahon, A Mahboubi, TC Saido, ... Journal of Biological Chemistry 270 (12), 6425-6428, 1995 | 678 | 1995 |
The E280A presenilin 1 Alzheimer mutation produces increased Aβ42 deposition and severe cerebellar pathology CA Lemere, F LoPERA, KS Kosik, CL Lendon, J OssA, TC Saido, ... Nature medicine 2 (10), 1146-1150, 1996 | 660 | 1996 |
ScaleS: an optical clearing palette for biological imaging H Hama, H Hioki, K Namiki, T Hoshida, H Kurokawa, F Ishidate, T Kaneko, ... Nature neuroscience 18 (10), 1518-1529, 2015 | 601 | 2015 |
The major risk factors for Alzheimer’s disease: age, sex, and genes modulate the microglia response to Aβ plaques CS Frigerio, L Wolfs, N Fattorelli, N Thrupp, I Voytyuk, I Schmidt, ... Cell reports 27 (4), 1293-1306. e6, 2019 | 598 | 2019 |
Developmental defects of lymphoid cells in Jak3 kinase-deficient mice SY Park, K Saijo, T Takahashi, M Osawa, H Areas, N Hirayama, K Miyake, ... Immunity 3 (6), 771-782, 1995 | 588 | 1995 |
Updated European Consensus Statement on diagnosis and treatment of adult ADHD JJS Kooij, D Bijlenga, L Salerno, R Jaeschke, I Bitter, J Balazs, J Thome, ... European psychiatry 56 (1), 14-34, 2019 | 570 | 2019 |
A phorbol ester receptor/protein kinase, nPKC eta, a new member of the protein kinase C family predominantly expressed in lung and skin. S Osada, K Mizuno, TC Saido, Y Akita, K Suzuki, T Kuroki, S Ohno Journal of Biological Chemistry 265 (36), 22434-22440, 1990 | 558 | 1990 |
Spatial transcriptomics and in situ sequencing to study Alzheimer’s disease WT Chen, A Lu, K Craessaerts, B Pavie, CS Frigerio, N Corthout, X Qian, ... Cell 182 (4), 976-991. e19, 2020 | 554 | 2020 |