| Accelerated neurodegeneration through chaperone-mediated oligomerization of tau LJ Blair, BA Nordhues, SE Hill, KM Scaglione, JC O’Leary, SN Fontaine, ... The Journal of clinical investigation 123 (10), 4158-4169, 2013 | 310 | 2013 |
| DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative‐associated proteins SN Fontaine, D Zheng, JJ Sabbagh, MD Martin, D Chaput, A Darling, ... The EMBO journal 35 (14), 1537-1549, 2016 | 207 | 2016 |
| Pathological tau promotes neuronal damage by impairing ribosomal function and decreasing protein synthesis S Meier, M Bell, DN Lyons, J Rodriguez-Rivera, A Ingram, SN Fontaine, ... Journal of Neuroscience 36 (3), 1001-1007, 2016 | 163 | 2016 |
| Age-associated epigenetic upregulation of the FKBP5 gene selectively impairs stress resiliency JJ Sabbagh, JC O'Leary III, LJ Blair, T Klengel, BA Nordhues, ... PloS one 9 (9), e107241, 2014 | 111 | 2014 |
| Cellular factors modulating the mechanism of tau protein aggregation SN Fontaine, JJ Sabbagh, J Baker, CR Martinez-Licha, A Darling, ... Cellular and molecular life sciences 72, 1863-1879, 2015 | 86 | 2015 |
| The effects of prion protein expression on metal metabolism S Kralovicova, SN Fontaine, A Alderton, J Alderman, KV Ragnarsdottir, ... Molecular and Cellular Neuroscience 41 (2), 135-147, 2009 | 65 | 2009 |
| Isoform-selective genetic inhibition of constitutive cytosolic Hsp70 activity promotes client tau degradation using an altered co-chaperone complement SN Fontaine, JN Rauch, BA Nordhues, VA Assimon, AR Stothert, ... Journal of Biological Chemistry 290 (21), 13115-13127, 2015 | 52 | 2015 |
| Targeting the ER-autophagy system in the trabecular meshwork to treat glaucoma AR Stothert, SN Fontaine, JJ Sabbagh, CA Dickey Experimental eye research 144, 38-45, 2016 | 51 | 2016 |
| Exploiting the interaction between Grp94 and aggregated myocilin to treat glaucoma AR Stothert, A Suntharalingam, DJE Huard, SN Fontaine, VM Crowley, ... Human Molecular Genetics 23 (24), 6470-6480, 2014 | 45 | 2014 |
| Spermidine/spermine-N1-acetyltransferase ablation impacts tauopathy-induced polyamine stress response LA Sandusky-Beltran, A Kovalenko, C Ma, JIT Calahatian, DS Placides, ... Alzheimer's Research & Therapy 11, 1-24, 2019 | 37 | 2019 |
| The active Hsc70/tau complex can be exploited to enhance tau turnover without damaging microtubule dynamics SN Fontaine, MD Martin, E Akoury, VA Assimon, S Borysov, BA Nordhues, ... Human molecular genetics 24 (14), 3971-3981, 2015 | 35 | 2015 |
| Aberrant AZIN2 and polyamine metabolism precipitates tau neuropathology LA Sandusky-Beltran, A Kovalenko, DS Placides, K Ratnasamy, C Ma, ... The Journal of Clinical Investigation 131 (4), 2021 | 27 | 2021 |
| Synthesis, stereochemical analysis, and derivatization of myricanol provide new probes that promote autophagic tau clearance MD Martin, L Calcul, C Smith, UK Jinwal, SN Fontaine, A Darling, ... ACS chemical biology 10 (4), 1099-1109, 2015 | 27 | 2015 |
| Identification of changes in neuronal function as a consequence of aging and tauopathic neurodegeneration using a novel and sensitive magnetic resonance imaging approach SN Fontaine, A Ingram, RA Cloyd, SE Meier, E Miller, D Lyons, GK Nation, ... Neurobiology of aging 56, 78-86, 2017 | 26 | 2017 |
| Neurodegeneration and the heat shock protein 70 machinery: implications for therapeutic development S N Fontaine, M D Martin, C A Dickey Current Topics in Medicinal Chemistry 16 (25), 2741-2752, 2016 | 21 | 2016 |
| Mechanisms of prion protein aggregation SN Fontaine, DR Brown Protein and peptide letters 16 (1), 14-26, 2009 | 19 | 2009 |
| Nuclear localization of clathrin involves a labile helix outside the trimerization domain JA Ybe, SN Fontaine, T Stone, J Nix, X Lin, S Mishra FEBS letters 587 (2), 142-149, 2013 | 10 | 2013 |
| Amyloidogenic metal-binding proteins: new investigative pathways P Davies, SN Fontaine, D Moualla, X Wang, JA Wright, DR Brown Biochemical Society Transactions 36 (6), 1299-1303, 2008 | 8 | 2008 |
| Unintended Formation of a 26-Membered Cycle in the Course of a Novel Approach to Myricanol, a Strained [7, 0]-metacyclophane P Massé, S Choppin, L Chiummiento, G Hanquet, F Colobert Synlett 31 (06), 559-564, 2020 | 7 | 2020 |
| Noncontact rotational head injury produces transient cognitive deficits but lasting neuropathological changes JJ Sabbagh, SN Fontaine, LB Shelton, LJ Blair, JB Hunt Jr, B Zhang, ... Journal of neurotrauma 33 (19), 1751-1760, 2016 | 7 | 2016 |
