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Natalie Connor-Robson
Natalie Connor-Robson
Career Development Fellow, University of Oxford
Verifierad e-postadress på dpag.ox.ac.uk
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Functional alterations to the nigrostriatal system in mice lacking all three members of the synuclein family
S Anwar, O Peters, S Millership, N Ninkina, N Doig, N Connor-Robson, ...
Journal of Neuroscience 31 (20), 7264-7274, 2011
2372011
Fused in Sarcoma (FUS) Protein Lacking Nuclear Localization Signal (NLS) and Major RNA Binding Motifs Triggers Proteinopathy and Severe Motor Phenotype in Transgenic Mice*♦
TA Shelkovnikova, OM Peters, AV Deykin, N Connor-Robson, ...
Journal of biological chemistry 288 (35), 25266-25274, 2013
1432013
LRRK2 interacts with the vacuolar-type H+-ATPase pump a1 subunit to regulate lysosomal function
R Wallings, N Connor-Robson, R Wade-Martins
Human molecular genetics 28 (16), 2696-2710, 2019
992019
LRRK2: autophagy and lysosomal activity
M Madureira, N Connor-Robson, R Wade-Martins
Frontiers in neuroscience 14, 536324, 2020
902020
Forced cell cycle exit and modulation of GABAA, CREB, and GSK3β signaling promote functional maturation of induced pluripotent stem cell-derived neurons
V Telezhkin, C Schnell, P Yarova, S Yung, E Cope, A Hughes, ...
American Journal of Physiology-Cell Physiology 310 (7), C520-C541, 2016
882016
Simultaneous and independent detection of C9ORF72 alleles with low and high number of GGGGCC repeats using an optimised protocol of Southern blot hybridisation
VL Buchman, J Cooper-Knock, N Connor-Robson, A Higginbottom, ...
Molecular neurodegeneration 8, 1-6, 2013
792013
Chronic administration of dimebon ameliorates pathology in Tau P301S transgenic mice
OM Peters, N Connor-Robson, VB Sokolov, AY Aksinenko, MS Kukharsky, ...
Journal of Alzheimer's disease 33 (4), 1041-1049, 2013
792013
LRRK2 BAC transgenic rats develop progressive, L-DOPA-responsive motor impairment, and deficits in dopamine circuit function
M Sloan, J Alegre-Abarrategui, D Potgieter, AK Kaufmann, R Exley, ...
Human molecular genetics 25 (5), 951-963, 2016
782016
Recruitment into stress granules prevents irreversible aggregation of FUS protein mislocalized to the cytoplasm
TA Shelkovnikova, HK Robinson, N Connor-Robson, VL Buchman
Cell Cycle 12 (19), 3383-3391, 2013
722013
An integrated transcriptomics and proteomics analysis reveals functional endocytic dysregulation caused by mutations in LRRK2
N Connor-Robson, H Booth, JG Martin, B Gao, K Li, N Doig, J Vowles, ...
Neurobiology of Disease 127, 512-526, 2019
682019
Are rodent models of Parkinson’s disease behaving as they should?
S Vingill, N Connor-Robson, R Wade-Martins
Behavioural Brain Research 352, 133-141, 2018
662018
RNA sequencing reveals MMP2 and TGFB1 downregulation in LRRK2 G2019S Parkinson's iPSC-derived astrocytes
HDE Booth, F Wessely, N Connor-Robson, F Rinaldi, J Vowles, C Browne, ...
Neurobiology of Disease 129, 56-66, 2019
632019
Combinational losses of synucleins reveal their differential requirements for compensating age-dependent alterations in motor behavior and dopamine metabolism
N Connor-Robson, OM Peters, S Millership, N Ninkina, VL Buchman
Neurobiology of Aging 46, 107-112, 2016
582016
CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson’s disease
N Bengoa-Vergniory, E Faggiani, P Ramos-Gonzalez, E Kirkiz, ...
Nature communications 11 (1), 4885, 2020
472020
Contrasting effects of α-synuclein and γ-synuclein on the phenotype of cysteine string protein α (CSPα) null mutant mice suggest distinct function of these proteins in neuronal …
N Ninkina, OM Peters, N Connor-Robson, O Lytkina, E Sharfeddin, ...
Journal of Biological Chemistry 287 (53), 44471-44477, 2012
452012
C9ORF72 transcription in a frontotemporal dementia case with two expanded alleles
J Cooper-Knock, A Higginbottom, N Connor-Robson, N Bayatti, JJ Bury, ...
Neurology 81 (19), 1719-1721, 2013
422013
GABA uptake transporters support dopamine release in dorsal striatum with maladaptive downregulation in a parkinsonism model
BM Roberts, NM Doig, KR Brimblecombe, EF Lopes, RE Siddorn, ...
Nature communications 11 (1), 4958, 2020
362020
A novel resource for studying function and dysfunction of α-synuclein: mouse lines for modulation of endogenous Snca gene expression
N Ninkina, N Connor-Robson, AA Ustyugov, TV Tarasova, ...
Scientific Reports 5 (1), 16615, 2015
292015
Striatal dopamine transporter function is facilitated by converging biology of α-Synuclein and cholesterol
S Threlfell, AS Mohammadi, BJ Ryan, N Connor-Robson, NJ Platt, ...
Frontiers in Cellular Neuroscience 15, 658244, 2021
202021
β-synuclein potentiates synaptic vesicle dopamine uptake and rescues dopaminergic neurons from MPTP-induced death in the absence of other synucleins
N Ninkina, SJ Millership, OM Peters, N Connor-Robson, K Chaprov, ...
Journal of Biological Chemistry 297 (6), 2021
142021
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Artiklar 1–20