Följ
Daniel J. Griffin
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Current and future roles of artificial intelligence in medicinal chemistry synthesis
TJ Struble, JC Alvarez, SP Brown, M Chytil, J Cisar, RL DesJarlais, ...
Journal of medicinal chemistry 63 (16), 8667-8682, 2020
1662020
Automated solubility screening platform using computer vision
P Shiri, V Lai, T Zepel, D Griffin, J Reifman, S Clark, S Grunert, ...
Iscience 24 (3), 2021
452021
Data-driven modeling and dynamic programming applied to batch cooling crystallization
DJ Griffin, MA Grover, Y Kawajiri, RW Rousseau
Industrial & Engineering Chemistry Research 55 (5), 1361-1372, 2016
432016
A virtual Plant for Integrated Continuous Manufacturing of a Carfilzomib drug substance intermediate, part 3: manganese-catalyzed asymmetric Epoxidation, crystallization, and …
AJ Maloney, E Içten, G Capellades, MG Beaver, X Zhu, LR Graham, ...
Organic Process Research & Development 24 (10), 1891-1908, 2020
282020
Optimal feedback control of batch self-assembly processes using dynamic programming
MA Grover, DJ Griffin, X Tang, Y Kim, RW Rousseau
Journal of Process Control 88, 32-42, 2020
192020
Mass-Count Plots for Crystal Size Control
DJ Griffin, MA Grover, Y Kawajiri, RW Rousseau
Chemical Engineering Science 137, 338-351, 2015
192015
Feedback control of multicomponent salt crystallization
DJ Griffin, Y Kawajiri, MA Grover, RW Rousseau
Crystal Growth & Design 15 (1), 305-317, 2015
192015
Robust Multicomponent IR-to-Concentration Model Regression
DJ Griffin, MA Grover, Y Kawajiri, RW Rousseau
Chemical Engineering Science 116, 77-90, 2014
192014
Axial chirality in the sotorasib drug substance, Part 1: Development of a classical resolution to prepare an atropisomerically pure sotorasib intermediate
AT Parsons, S Caille, MA Caporini, DJ Griffin, MA Lovette, W Powazinik IV, ...
Organic Process Research & Development 26 (9), 2629-2635, 2022
162022
Accelerated development of a scalable ring-closing metathesis to manufacture AMG 176 using a combined high-throughput experimentation and computational modeling approach
G St-Pierre, AH Cherney, W Chen, X Dong, PK Dornan, DJ Griffin, ...
Organic Process Research & Development 25 (3), 442-451, 2020
162020
Using MC plots for control of paracetamol crystallization
DJ Griffin, Y Kawajiri, RW Rousseau, MA Grover
Chemical Engineering Science 164, 344-360, 2017
162017
Development of a Commercial Manufacturing Process for Sotorasib, a First-in-Class KRASG12C Inhibitor
L Zhang, DJ Griffin, MG Beaver, LE Blue, CJ Borths, DB Brown, S Caille, ...
Organic Process Research & Development 26 (11), 3115-3125, 2022
152022
Combining ATR-FTIR and FBRM for Feedback on Crystal Size
DJ Griffin, MA Grover, Y Kawajiri, RW Rousseau
American Control Conference, Chicago IL., 2015
92015
Externally directing self-assembly with dynamic programming
DJ Griffin, X Tang, MA Grover
2016 American Control Conference (ACC), 3086-3091, 2016
52016
Liquid/liquid heterogeneous reaction monitoring: Insights into biphasic Suzuki-Miyaura cross-coupling
Y Sato, J Liu, IE Ndukwe, MVS Elipe, DJ Griffin, JI Murray, JE Hein
Chem Catalysis 3 (7), 2023
42023
Control of self-assembly with dynamic programming
MA Grover, DJ Griffin, X Tang
IFAC-PapersOnLine 52 (1), 1-9, 2019
42019
Opportunities for Machine Learning and Artificial Intelligence to Advance Synthetic Drug Substance Process Development
DJ Griffin, CW Coley, SA Frank, JM Hawkins, KF Jensen
Organic Process Research & Development 27 (11), 1868-1879, 2023
32023
A framework for understanding and controlling batch cooling crystallization
DJ Griffin
Ph. D. thesis, Georgia Institute of Technology, 2016
32016
A Continuous Process for Manufacturing Apremilast. Part I: Process Development and Intensification by Utilizing Flow Chemistry Principles
HW Hsieh, CM Cohen, DJ Griffin, P Ananthoji, NH Avci, DB Brown, ...
Organic Process Research & Development, 2024
12024
Developing and Optimizing a Quench-Crystallization Operation in Drug Substance Manufacturing
DJ Griffin, L Zhang, JD Fostinis, AT Parsons
Organic Process Research & Development 27 (8), 1499-1509, 2023
12023
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Artiklar 1–20