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Lee Albacker
Lee Albacker
Director, Foundation Medicine Inc.
Verifierad e-postadress på foundationmedicine.com
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Tissue expression of PD-L1 mediates peripheral T cell tolerance
ME Keir, SC Liang, I Guleria, YE Latchman, A Qipo, LA Albacker, ...
The Journal of experimental medicine 203 (4), 883-895, 2006
14262006
STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung Adenocarcinoma
F Skoulidis, ME Goldberg, DM Greenawalt, MD Hellmann, MM Awad, ...
Cancer discovery 8 (7), 822-835, 2018
12292018
Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity
YJ Chang, HY Kim, LA Albacker, N Baumgarth, ANJ McKenzie, DE Smith, ...
Nature immunology 12 (7), 631-638, 2011
8952011
Mechanisms and therapeutic implications of hypermutation in gliomas
M Touat, YY Li, AN Boynton, LF Spurr, JB Iorgulescu, CL Bohrson, ...
Nature 580 (7804), 517-523, 2020
4372020
PD-L1 expression and tumor mutational burden are independent biomarkers in most cancers
M Yarchoan, LA Albacker, AC Hopkins, M Montesion, K Murugesan, ...
JCI insight 4 (6), 2019
4082019
Innate lymphoid cells responding to IL-33 mediate airway hyperreactivity independently of adaptive immunity
HY Kim, YJ Chang, S Subramanian, HH Lee, LA Albacker, ...
Journal of Allergy and Clinical Immunology 129 (1), 216-227. e6, 2012
3592012
Activation mechanism of oncogenic deletion mutations in BRAF, EGFR, and HER2
SA Foster, DM Whalen, A Özen, MJ Wongchenko, JP Yin, I Yen, ...
Cancer cell 29 (4), 477-493, 2016
2012016
Association of circulating tumor DNA and circulating tumor cells after neoadjuvant chemotherapy with disease recurrence in patients with triple-negative breast cancer …
M Radovich, G Jiang, BA Hancock, C Chitambar, R Nanda, C Falkson, ...
JAMA oncology 6 (9), 1410-1415, 2020
1902020
Influenza infection in suckling mice expands an NKT cell subset that protects against airway hyperreactivity
YJ Chang, HY Kim, LA Albacker, HH Lee, N Baumgarth, S Akira, ...
The Journal of clinical investigation 121 (1), 57-69, 2011
1792011
Pan-cancer landscape and analysis of ERBB2 mutations identifies poziotinib as a clinically active inhibitor and enhancer of T-DM1 activity
JP Robichaux, YY Elamin, RSK Vijayan, MB Nilsson, L Hu, J He, F Zhang, ...
Cancer Cell 36 (4), 444-457. e7, 2019
1562019
Invariant natural killer T cells recognize a fungal glycosphingolipid that can induce airway hyperreactivity
LA Albacker, V Chaudhary, YJ Chang, HY Kim, YT Chuang, M Pichavant, ...
Nature medicine 19 (10), 1297-1304, 2013
1532013
Emergence of novel and dominant acquired EGFR solvent-front mutations at Gly796 (G796S/R) together with C797S/G and L792F/H mutations in one EGFR (L858R/T790M) NSCLC patient …
SHI Ou, J Cui, AB Schrock, ME Goldberg, VW Zhu, L Albacker, ...
Lung cancer 108, 228-231, 2017
1512017
Somatic HLA class I loss is a widespread mechanism of immune evasion which refines the use of tumor mutational burden as a biomarker of checkpoint inhibitor response
M Montesion, K Murugesan, DX Jin, R Sharaf, N Sanchez, A Guria, ...
Cancer Discovery 11 (2), 282-292, 2021
1502021
The genomic landscape of Merkel cell carcinoma and clinicogenomic biomarkers of response to immune checkpoint inhibitor therapy
TC Knepper, M Montesion, JS Russell, ES Sokol, GM Frampton, VA Miller, ...
Clinical Cancer Research 25 (19), 5961-5971, 2019
1372019
Oncogene-specific differences in tumor mutational burden, PD-L1 expression, and outcomes from immunotherapy in non-small cell lung cancer
MV Negrao, F Skoulidis, M Montesion, K Schulze, I Bara, V Shen, H Xu, ...
Journal for immunotherapy of cancer 9 (8), 2021
1302021
Comprehensive genomic profiling facilitates implementation of the national comprehensive cancer network guidelines for lung cancer biomarker testing and identifies patients who …
JH Suh, A Johnson, L Albacker, K Wang, J Chmielecki, G Frampton, ...
The Oncologist 21 (6), 684-691, 2016
1192016
High-throughput genomic profiling of adult solid tumors reveals novel insights into cancer pathogenesis
RJ Hartmaier, LA Albacker, J Chmielecki, M Bailey, J He, ME Goldberg, ...
Cancer research 77 (9), 2464-2475, 2017
1082017
TIM-4, a receptor for phosphatidylserine, controls adaptive immunity by regulating the removal of antigen-specific T cells
LA Albacker, P Karisola, YJ Chang, SE Umetsu, M Zhou, O Akbari, ...
The Journal of Immunology 185 (11), 6839-6849, 2010
1062010
Loss of function JAK1 mutations occur at high frequency in cancers with microsatellite instability and are suggestive of immune evasion
LA Albacker, J Wu, P Smith, M Warmuth, PJ Stephens, P Zhu, L Yu, ...
PloS one 12 (11), e0176181, 2017
972017
Deletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma
F Foijer, LA Albacker, B Bakker, DC Spierings, Y Yue, SZ Xie, S Davis, ...
Elife 6, e20873, 2017
732017
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Artiklar 1–20