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Elin Boger
Elin Boger
AstraZeneca, University of Warwick
Verifierad e-postadress på astrazeneca.com
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Systems pharmacology approach for prediction of pulmonary and systemic pharmacokinetics and receptor occupancy of inhaled drugs
E Boger, N Evans, M Chappell, A Lundqvist, P Ewing, A Wigenborg, ...
CPT: pharmacometrics & systems pharmacology 5 (4), 201-210, 2016
772016
Physiologically based pharmacokinetic/pharmacodynamic modeling accurately predicts the better bronchodilatory effect of inhaled versus oral salbutamol dosage forms
E Boger, M Fridén
Journal of aerosol medicine and pulmonary drug delivery 32 (1), 1-12, 2019
492019
Development of a novel lung slice methodology for profiling of inhaled compounds
E Bäckström, A Lundqvist, E Boger, P Svanberg, P Ewing, ...
Journal of pharmaceutical sciences 105 (2), 838-845, 2016
462016
Lung retention by lysosomal trapping of inhaled drugs can be predicted in vitro with lung slices
E Bäckström, E Boger, A Lundqvist, M Hammarlund-Udenaes, M Fridén
Journal of pharmaceutical sciences 105 (11), 3432-3439, 2016
282016
A novel in vivo receptor occupancy methodology for the glucocorticoid receptor: toward an improved understanding of lung pharmacokinetic/pharmacodynamic relationships
E Boger, P Ewing, UG Eriksson, BM Fihn, M Chappell, N Evans, M Fridén
Journal of Pharmacology and Experimental Therapeutics 353 (2), 279-287, 2015
192015
A partial differential equation approach to inhalation physiologically based pharmacokinetic modeling
E Boger, O Wigström
CPT: Pharmacometrics & Systems Pharmacology 7 (10), 638-646, 2018
142018
Systems pharmacology approach for prediction of pulmonary and systemic pharmacokinetics and receptor occupancy of inhaled drugs. CPT: Pharmacomet Syst Pharmacol 5 (4): 201–210
E Boger, N Evans, M Chappell, A Lundqvist, P Ewing, A Wigenborg, ...
32016
Assessment of Epithelial Lining Fluid Partitioning of Systemically Administered Monoclonal Antibodies in Rats
E Boger, T Erngren, BM Fihn, E Leonard, K Rubin, E Bäckström
Journal of Pharmaceutical Sciences 112 (4), 1130-1136, 2023
2023
Lung-targeted receptor occupancy by drug inhalation: an experimental and computational evaluation.
E Boger
University of Warwick, 2016
2016
Tissue distribution of inhalation drugs in rat lung slices
E Bäckström, A Lundqvist, E Boger, P Svanberg, P Ewing, ...
European Respiratory Journal 46 (suppl 59), 2015
2015
Lung absorption half-life of inhaled drugs can be predicted with rat lung slices
E Bäckström, A Lundqvist, E Boger, M Hammarlund-Udenaes, M Friden
European Respiratory Journal 46 (suppl 59), 2015
2015
Development of a lung slice methodology to study the mechanisms of lung uptake and lysosomal trapping
E Bäckström, A Lundqvist, P Svanberg, E Boger, P Ewing, ...
European Respiratory Journal 44 (Suppl 58), 2014
2014
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Artiklar 1–12