Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors CA Bradbury, FL Khanim, R Hayden, CM Bunce, DA White, MT Drayson, ... Leukemia 19 (10), 1751-1759, 2005 | 519 | 2005 |
Analysis of Epstein-Barr virus gene polymorphisms in normal donors and in virus-associated tumors from different geographic locations F Khanim, QY Yao, G Niedobitek, S Sihota, AB Rickinson, LS Young | 242 | 1996 |
Clinical and molecular genetic analysis of 19 Wolfram syndrome kindreds demonstrating a wide spectrum of mutations in WFS1 C Hardy, F Khanim, R Torres, M Scott-Brown, A Seller, J Poulton, ... The American Journal of Human Genetics 65 (5), 1279-1290, 1999 | 236 | 1999 |
HLA A2. 1-restricted cytotoxic T cells recognizing a range of Epstein-Barr virus isolates through a defined epitope in latent membrane protein LMP2. SP Lee, WA Thomas, RJ Murray, F Khanim, S Kaur, LS Young, M Rowe, ... Journal of virology 67 (12), 7428-7435, 1993 | 226 | 1993 |
WFS1/wolframin mutations, Wolfram syndrome, and associated diseases F Khanim, J Kirk, F Latif, TG Barrett Human mutation 17 (5), 357-367, 2001 | 204 | 2001 |
PEP005, a selective small-molecule activator of protein kinase C, has potent antileukemic activity mediated via the delta isoform of PKC P Hampson, H Chahal, F Khanim, R Hayden, A Mulder, LK Assi, ... Blood 106 (4), 1362-1368, 2005 | 169 | 2005 |
Metabolomic profiling of drug responses in acute myeloid leukaemia cell lines S Tiziani, A Lodi, FL Khanim, MR Viant, CM Bunce, UL Günther PloS one 4 (1), e4251, 2009 | 156 | 2009 |
Altered SMRT levels disrupt vitamin D 3 receptor signalling in prostate cancer cells FL Khanim, LM Gommersall, VHJ Wood, KL Smith, L Montalvo, LP O'Neill, ... Oncogene 23 (40), 6712-6725, 2004 | 155 | 2004 |
Slug regulates integrin expression and cell proliferation in human epidermal keratinocytes FE Turner, S Broad, FL Khanim, A Jeanes, S Talma, S Hughes, ... Journal of Biological Chemistry 281 (30), 21321-21331, 2006 | 120 | 2006 |
Redeployment-based drug screening identifies the anti-helminthic niclosamide as anti-myeloma therapy that also reduces free light chain production FL Khanim, B Merrick, HV Giles, M Jankute, JB Jackson, LJ Giles, ... Blood cancer journal 1 (10), e39-e39, 2011 | 97 | 2011 |
The aldo-keto reductase AKR1C3 contributes to 7, 12-dimethylbenz (a) anthracene-3, 4-dihydrodiol mediated oxidative DNA damage in myeloid cells: implications for leukemogenesis J Birtwistle, RE Hayden, FL Khanim, RM Green, C Pearce, NJ Davies, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 662 (1 …, 2009 | 93 | 2009 |
Metabolic plasticity in CLL: adaptation to the hypoxic niche KM Koczula, C Ludwig, R Hayden, L Cronin, G Pratt, H Parry, D Tennant, ... Leukemia 30 (1), 65-73, 2016 | 91 | 2016 |
The role of repetitive DNA sequences in the size variation of Epstein—Barr virus (EBV) nuclear antigens, and the identification of different EBV isolates using RFLP and PCR … K Falk, JW Gratama, M Rowe, JZ Zou, F Khanim, LS Young, ... Journal of General Virology 76 (4), 779-790, 1995 | 88 | 1995 |
Combined bezafibrate and medroxyprogesterone acetate: potential novel therapy for acute myeloid leukaemia FL Khanim, RE Hayden, J Birtwistle, A Lodi, S Tiziani, NJ Davies, JP Ride, ... PLoS One 4 (12), e8147, 2009 | 83 | 2009 |
BHRF1, a viral homologue of the Bcl-2 oncogene, is conserved at both the sequence and functional level in different Epstein-Barr virus isolates. F Khanim, C Dawson, CA Meseda, J Dawson, M Mackett, LS Young Journal of General Virology 78 (11), 2987-2999, 1997 | 81 | 1997 |
Elevated NCOR1 disrupts PPARα/γ signaling in prostate cancer and forms a targetable epigenetic lesion S Battaglia, O Maguire, JL Thorne, LB Hornung, CL Doig, S Liu, ... Carcinogenesis 31 (9), 1650-1660, 2010 | 70 | 2010 |
Crosstalk between plasmid vegetative replication and conjugative transfer: repression of the trfA operon by trbA of broad host range … G Jagura-Burdzy, F Khanim, CA Smith, CM Thomas Nucleic Acids Research 20 (15), 3939-3944, 1992 | 67 | 1992 |
Drug redeployment to kill leukemia and lymphoma cells by disrupting SCD1-mediated synthesis of monounsaturated fatty acids AD Southam, FL Khanim, RE Hayden, JK Constantinou, KM Koczula, ... Cancer Research 75 (12), 2530-2540, 2015 | 66 | 2015 |
Proton NMR-based metabolite analyses of archived serial paired serum and urine samples from myeloma patients at different stages of disease activity identifies acetylcarnitine … A Lodi, S Tiziani, FL Khanim, UL Günther, MR Viant, GJ Morgan, ... PloS one 8 (2), e56422, 2013 | 59 | 2013 |
The anthelmintic drug niclosamide and its analogues activate the Parkinson's disease associated protein kinase PINK1 E Barini, A Miccoli, F Tinarelli, K Mulholland, H Kadri, F Khanim, ... ChemBioChem 19 (5), 425-429, 2018 | 56 | 2018 |