Följ
Tommaso Costa
Tommaso Costa
Verifierad e-postadress på iss.it
Titel
Citeras av
Citeras av
År
A mutation-induced activated state of the beta 2-adrenergic receptor. Extending the ternary complex model.
P Samama, S Cotecchia, T Costa, RJ Lefkowitz
Journal of Biological Chemistry 268 (7), 4625-4636, 1993
15781993
Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins
RJ Lefkowitz, S Cotecchia, P Samama, T Costa
Trends in pharmacological sciences 14 (8), 303-307, 1993
10221993
Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins.
T Costa, A Herz
Proceedings of the National Academy of Sciences 86 (19), 7321-7325, 1989
6891989
Constitutively active mutants of the alpha 1B‐adrenergic receptor: role of highly conserved polar amino acids in receptor activation.
A Scheer, F Fanelli, T Costa, PG De Benedetti, S Cotecchia
The EMBO Journal 15 (14), 3566-3578, 1996
4751996
Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation
DP Staus, RT Strachan, A Manglik, B Pani, AW Kahsai, TH Kim, ...
Nature 535 (7612), 448-452, 2016
3162016
Drug efficacy at guanine nucleotide-binding regulatory protein-linked receptors: thermodynamic interpretation of negative antagonism and of receptor activity in the absence of …
T Costa, Y Ogino, PJ Munson, HO Onaran, D Rodbard
Molecular Pharmacology 41 (3), 549-560, 1992
3031992
Negative antagonists promote an inactive conformation of the beta 2-adrenergic receptor.
P Samama, G Pei, T Costa, S Cotecchia, RJ Lefkowitz
Molecular pharmacology 45 (3), 390-394, 1994
3001994
The activation process of the α1B-adrenergic receptor: Potential role of protonation and hydrophobicity of a highly conserved aspartate
A Scheer, F Fanelli, T Costa, PG De Benedetti, S Cotecchia
Proceedings of the National Academy of Sciences 94 (3), 808-813, 1997
2711997
Is the benzodiazepine receptor coupled to a chloride anion channel?
T Costa, D Rodbard, CB PERT
Nature 277 (5694), 315-317, 1979
2501979
Spontaneous association between opioid receptors and GTP-binding regulatory proteins in native membranes: specific regulation by antagonists and sodium ions.
T Costa, J Lang, C Gless, A Herz
Molecular pharmacology 37 (3), 383-394, 1990
1761990
Historical review: Negative efficacy and the constitutive activity of G-protein-coupled receptors
T Costa, S Cotecchia
Trends in pharmacological sciences 26 (12), 618-624, 2005
1652005
Mutational analysis of the highly conserved arginine within the Glu/Asp-Arg-Tyr motif of the α1b-adrenergic receptor: effects on receptor isomerization and activation
A Scheer, T Costa, F Fanelli, PG De Benedetti, S Mhaouty-Kodja, L Abuin, ...
Molecular pharmacology 57 (2), 219-231, 2000
1482000
Opiate receptor binding sites in human spinal cord
A Członkowski, T Costa, R Przewłocki, A Pasi, A Herz
Brain Research 267 (2), 392-396, 1983
1371983
Dimeric tetrapeptide enkephalins display extraordinary selectivity for the δ opiate receptor
Y Shimohigashi, T Costa, HC Chen, D Rodbard
Nature 297 (5864), 333-335, 1982
1351982
Morphine-like opiates selectively antagonize receptor-arrestin interactions
P Molinari, V Vezzi, M Sbraccia, C Grō, D Riitano, C Ambrosio, I Casella, ...
Journal of biological chemistry 285 (17), 12522-12535, 2010
1332010
Thrombin is a regulator of astrocytic endothelin-1
H Ehrenreich, T Costa, KA Clouse, RM Pluta, Y Ogino, JE Coligan, ...
Brain research 600 (2), 201-207, 1993
1261993
Divergent transducer-specific molecular efficacies generate biased agonism at a G protein-coupled receptor (GPCR)
RT Strachan, J Sun, DH Rominger, JD Violin, S Ahn, ARB Thomsen, ...
Journal of Biological Chemistry 289 (20), 14211-14224, 2014
1252014
Agonist Efficacy and Aliosteric Models of Receptor Actiona
HO Onaran, T Costa
Annals of the new York Academy of Sciences 812 (1), 98-115, 1997
1141997
Highly potent nociceptin analog containing the Arg-Lys triple repeat
K Okada, T Sujaku, Y Chuman, R Nakashima, T Nose, T Costa, ...
Biochemical and biophysical research communications 278 (2), 493-498, 2000
1122000
Direct modulation of voltage-dependent calcium channels by muscarinic activation of a pertussis toxin-sensitive G-protein in hippocampal neurons
M Toselli, J Lang, T Costa, HD Lux
Pflügers Archiv 415, 255-261, 1989
1031989
Systemet kan inte utföra åtgärden just nu. Försök igen senare.
Artiklar 1–20