Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities CM Gay, CA Stewart, EM Park, L Diao, SM Groves, S Heeke, BY Nabet, ... Cancer cell 39 (3), 346-360. e7, 2021 | 514 | 2021 |
Systems-level network modeling of Small Cell Lung Cancer subtypes identifies master regulators and destabilizers DJ Wooten, SM Groves, DR Tyson, Q Liu, JS Lim, R Albert, CF Lopez, ... PLoS computational biology 15 (10), e1007343, 2019 | 86 | 2019 |
Consistency of electron scattering data with a small proton radius K Griffioen, C Carlson, S Maddox Physical Review C 93 (6), 065207, 2016 | 73 | 2016 |
ASCL1 represses a SOX9+ neural crest stem-like state in small cell lung cancer RR Olsen, AS Ireland, DW Kastner, SM Groves, KB Spainhower, K Pozo, ... Genes & Development 35 (11-12), 847-869, 2021 | 35 | 2021 |
Archetype tasks link intratumoral heterogeneity to plasticity and cancer hallmarks in small cell lung cancer SM Groves, GV Ildefonso, CO McAtee, PMM Ozawa, AS Ireland, ... Cell systems 13 (9), 690-710. e17, 2022 | 21 | 2022 |
Beyond programmed death-ligand 1: B7-H6 emerges as a potential immunotherapy target in SCLC PL Thomas, SM Groves, YK Zhang, J Li, P Gonzalez-Ericsson, ... Journal of Thoracic Oncology 16 (7), 1211-1223, 2021 | 17 | 2021 |
Cancer hallmarks define a continuum of plastic cell states between small cell lung cancer archetypes SM Groves, A Ireland, Q Liu, AJ Simmons, K Lau, WT Iams, D Tyson, ... BioRxiv, 2021.01. 22.427865, 2021 | 14 | 2021 |
Are Electron Scattering Data Consistent with a Small Proton Radius? K Griffioen, C Carlson, S Maddox arXiv preprint arXiv:1509.06676, 2015 | 6 | 2015 |
Involvement of Epithelial–Mesenchymal Transition Genes in Small Cell Lung Cancer Phenotypic Plasticity SM Groves, N Panchy, DR Tyson, LA Harris, V Quaranta, T Hong Cancers 15 (5), 1477, 2023 | 5 | 2023 |
CXCR2 expression during melanoma tumorigenesis controls transcriptional programs that facilitate tumor growth J Yang, K Bergdorf, C Yan, W Luo, SC Chen, GD Ayers, Q Liu, X Liu, ... Molecular Cancer 22 (1), 92, 2023 | 3 | 2023 |
Beyond PD-L1: B7-H6 emerges as a potential immunotherapy target in small cell lung cancer PL Thomas, SM Groves, YK Zhang, J Li, P Gonzalez-Ericsson, ... Journal of thoracic oncology: official publication of the International …, 2021 | 2 | 2021 |
Small cell lung cancer subtypes identified by systems-level modeling of transcription factor networks D Wooten, S Maddox, D Tyson, Q Liu, JS Lim, J Sage, V Quaranta Preprint at bioRxiv https://www. biorxiv. org/content/10.1101/506402v2, 2018 | 2 | 2018 |
Quantifying Cancer Cell Plasticity with Gene Regulatory Networks and Single-Cell Dynamics SM Groves, V Quaranta Frontiers in Network Physiology 3, 1225736, 2023 | 1 | 2023 |
Network Control of Cell Identity and Plasticity in Small Cell Lung Cancer SM Groves Vanderbilt University, 2022 | 1 | 2022 |
ASCL1 represses a latent osteogenic program in small cell lung Cancer in multiple cells of origin RR Olsen, DW Kastner, AS Ireland, SM Groves, K Pozo, CP Whitney, ... bioRxiv, 2020.11. 11.362632, 2020 | 1 | 2020 |
YAP1 defines a highly plastic, persister cell population in small cell lung cancer (SCLC) following relapse CA Stewart, SM Groves, R Wang, K Ramkumar, Y Xi, L Diao, AG Serrano, ... Cancer Research 84 (6_Supplement), 5864-5864, 2024 | | 2024 |
Analysis of extracellular vesicle surface markers as small cell lung cancer biomarkers PM Ozawa, SM Groves, V Quaranta, AM Weaver Cancer Research 83 (7_Supplement), 5308-5308, 2023 | | 2023 |
Analysis of transcriptome datasets reveals involvement of epithelial-mesenchymal transition genes in small cell lung cancer phenotypic plasticity SM Groves, N Panchy, DR Tyson, LA Harris, V Quaranta, T Hong bioRxiv, 2022.09. 09.507376, 2022 | | 2022 |
Evaluation of immune checkpoints in small cell lung cancer: implications for immunotherapy P Thomas, S Maddox, W Iams, V Quaranta, D Tyson, C Lovly The Journal of Immunology 204 (1_Supplement), 165.39-165.39, 2020 | | 2020 |
A Computational Model of Subtype Interactions in Small Cell Lung Cancer Predicts Factors Controlling Intertumoral Heterogeneity LA Harris, S Beik, SM Groves, AM Weaver, CF Lopez, V Quaranta 2019 AIChE Annual Meeting, 2019 | | 2019 |