Follow
Ismael Compañón Pérez
Ismael Compañón Pérez
Other namesIsmael Companon
Investigador en Química, Universidad de La Rioja
Verified email at unirioja.es
Title
Cited by
Cited by
Year
Dynamic interplay between catalytic and lectin domains of GalNAc-transferases modulates protein O-glycosylation
E Lira-Navarrete, M de Las Rivas, I Compañón, MC Pallarés, Y Kong, ...
Nature communications 6 (1), 6937, 2015
962015
Substrate‐Guided Front‐Face Reaction Revealed by Combined Structural Snapshots and Metadynamics for the Polypeptide N‐Acetylgalactosaminyltransferase 2
E Lira‐Navarrete, J Iglesias‐Fernández, WF Zandberg, I Compañón, ...
Angewandte Chemie 126 (31), 8345-8349, 2014
952014
Deciphering the Non‐Equivalence of Serine and Threonine O‐Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti‐MUC1 …
N Martínez‐Sáez, J Castro‐López, J Valero‐González, D Madariaga, ...
Angewandte Chemie International Edition 54 (34), 9830-9834, 2015
832015
Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine‐Selective Protein Modification and Charge Modulation
MJ Matos, CD Navo, T Hakala, X Ferhati, A Guerreiro, D Hartmann, ...
Angewandte Chemie International Edition 58 (20), 6640-6644, 2019
672019
Structure-based design of potent tumor-associated antigens: modulation of peptide presentation by single-atom O/S or O/Se substitutions at the glycosidic linkage
I Compañón, A Guerreiro, V Mangini, J Castro-López, M Escudero-Casao, ...
Journal of the American Chemical Society 141 (9), 4063-4072, 2019
642019
Efficient and irreversible antibody–cysteine bioconjugation using carbonylacrylic reagents
B Bernardim, MJ Matos, X Ferhati, I Compañón, A Guerreiro, P Akkapeddi, ...
Nature Protocols 14 (1), 86-99, 2019
622019
Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3
M de Las Rivas, EJ Paul Daniel, Y Narimatsu, I Compañón, K Kato, ...
Nature chemical biology 16 (3), 351-360, 2020
572020
Oxetane Grafts Installed Site‐Selectively on Native Disulfides to Enhance Protein Stability and Activity In Vivo
N Martínez‐Sáez, S Sun, D Oldrini, P Sormanni, O Boutureira, F Carboni, ...
Angewandte Chemie International Edition 56 (47), 14963-14967, 2017
542017
S-Michael Additions to Chiral Dehydroalanines as an Entry to Glycosylated Cysteines and a Sulfa-Tn Antigen Mimic
C Aydillo, I Companon, A Avenoza, JH Busto, F Corzana, JM Peregrina, ...
Journal of the American Chemical Society 136 (2), 789-800, 2014
502014
Water sculpts the distinctive shapes and dynamics of the tumor-associated carbohydrate Tn antigens: Implications for their molecular recognition
IA Bermejo, I Usabiaga, I Compañón, J Castro-López, A Insausti, ...
Journal of the American Chemical Society 140 (31), 9952-9960, 2018
422018
The use of fluoroproline in MUC1 antigen enables efficient detection of antibodies in patients with prostate cancer
VJ Somovilla, IA Bermejo, IS Albuquerque, N Martinez-Saez, ...
Journal of the American Chemical Society 139 (50), 18255-18261, 2017
422017
The interdomain flexible linker of the polypeptide GalNAc transferases dictates their long-range glycosylation preferences
M de Las Rivas, E Lira-Navarrete, EJP Daniel, I Compañón, H Coelho, ...
Nature communications 8 (1), 1959, 2017
402017
Structural and mechanistic insights into the catalytic-domain-mediated short-range glycosylation preferences of GalNAc-T4
M de Las Rivas, EJ Paul Daniel, H Coelho, E Lira-Navarrete, L Raich, ...
ACS Central Science 4 (9), 1274-1290, 2018
372018
Efficient Amino‐Sulfhydryl Stapling on Peptides and Proteins Using Bifunctional NHS‐Activated Acrylamides
MJSA Silva, H Faustino, JAS Coelho, MV Pinto, A Fernandes, ...
Angewandte Chemie International Edition 60 (19), 10850-10857, 2021
312021
Design of α-S-Neoglycopeptides Derived from MUC1 with a Flexible and Solvent-Exposed Sugar Moiety
V Rojas-Ocáriz, I Compañón, C Aydillo, J Castro-Lopez, ...
The Journal of Organic Chemistry 81 (14), 5929-5941, 2016
242016
Structural Analysis of a GalNAc‐T2 Mutant Reveals an Induced‐Fit Catalytic Mechanism for GalNAc‐Ts
M de Las Rivas, H Coelho, A Diniz, E Lira‐Navarrete, I Compañón, ...
Chemistry–A European Journal 24 (33), 8382-8392, 2018
212018
Structural and mechanistic insights into the cleavage of clustered O-glycan patches-containing glycoproteins by mucinases of the human gut
V Taleb, Q Liao, Y Narimatsu, A García-García, I Compañón, RJ Borges, ...
Nature communications 13 (1), 4324, 2022
192022
Cell‐Penetrating Peptides Containing Fluorescent d‐Cysteines
CD Navo, A Asín, E Gómez‐Orte, MI Gutiérrez‐Jiménez, I Compañón, ...
Chemistry–A European Journal 24 (31), 7991-8000, 2018
172018
Enhanced Permeability and Binding Activity of Isobutylene‐Grafted Peptides
S Sun, I Compañón, N Martínez‐Sáez, JD Seixas, O Boutureira, ...
ChemBioChem 19 (1), 48-52, 2018
162018
Atomic and Specificity Details of Mucin 1 O-Glycosylation Process by Multiple Polypeptide GalNAc-Transferase Isoforms Unveiled by NMR and Molecular Modeling
H Coelho, M Rivas, AS Grosso, A Diniz, CO Soares, RA Francisco, ...
Jacs Au 2 (3), 631-645, 2022
132022
The system can't perform the operation now. Try again later.
Articles 1–20