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Guillaume P. Andrieu
Guillaume P. Andrieu
Researcher, Institut Necker-Enfants Malades, Paris, France
Verifierad e-postadress på inserm.fr
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Clinical trials for BET inhibitors run ahead of the science
G Andrieu, AC Belkina, GV Denis
Drug Discovery Today: Technologies 19, 45-50, 2016
2602016
BRD4 regulates breast cancer dissemination through Jagged1/Notch1 signaling
G Andrieu, AH Tran, KJ Strissel, GV Denis
Cancer research 76 (22), 6555-6567, 2016
1272016
Osteoblast-derived sphingosine 1-phosphate to induce proliferation and confer resistance to therapeutics to bone metastasis-derived prostate cancer cells
L Brizuela, C Martin, P Jeannot, I Ader, C Gstalder, G Andrieu, M Bocquet, ...
Molecular oncology 8 (7), 1181-1195, 2014
782014
BET proteins exhibit transcriptional and functional opposition in the epithelial-to-mesenchymal transition
GP Andrieu, GV Denis
Molecular Cancer Research 16 (4), 580-586, 2018
552018
BRD4 regulates metastatic potential of castration-resistant prostate cancer through AHNAK
JS Shafran, GP Andrieu, B Györffy, GV Denis
Molecular Cancer Research 17 (8), 1627-1638, 2019
472019
BET protein targeting suppresses the PD-1/PD-L1 pathway in triple-negative breast cancer and elicits anti-tumor immune response
GP Andrieu, JS Shafran, CL Smith, AC Belkina, AN Casey, N Jafari, ...
Cancer letters 465, 45-58, 2019
462019
Neutralizing S1P inhibits intratumoral hypoxia, induces vascular remodelling and sensitizes to chemotherapy in prostate cancer
I Ader, C Gstalder, P Bouquerel, M Golzio, G Andrieu, S Zalvidea, ...
Oncotarget 6 (15), 13803, 2015
432015
Sphingosine 1-phosphate signaling through its receptor S1P5 promotes chromosome segregation and mitotic progression
G Andrieu, A Ledoux, S Branka, M Bocquet, J Gilhodes, T Walzer, ...
Science signaling 10 (472), eaah4007, 2017
422017
BET proteins in abnormal metabolism, inflammation, and the breast cancer microenvironment
GP Andrieu, JS Shafran, JT Deeney, KR Bharadwaj, A Rangarajan, ...
Journal of leukocyte biology 104 (2), 265-274, 2018
402018
BET bromodomain proteins and epigenetic regulation of inflammation: implications for type 2 diabetes and breast cancer
DA Nicholas, G Andrieu, KJ Strissel, BS Nikolajczyk, GV Denis
Cellular and Molecular Life Sciences 74, 231-243, 2017
332017
PRC2 loss of function confers a targetable vulnerability to BET proteins in T-ALL
GP Andrieu, M Kohn, M Simonin, CL Smith, A Cieslak, MÉ Dourthe, ...
Blood, The Journal of the American Society of Hematology 138 (19), 1855-1869, 2021
262021
The GTPase Gem and its partner Kif9 are required for chromosome alignment, spindle length control, and mitotic progression
G Andrieu, M Quaranta, C Leprince, A Hatzoglou
The FASEB Journal 26 (12), 5025-5034, 2012
262012
Blueprint of human thymopoiesis reveals molecular mechanisms of stage-specific TCR enhancer activation
A Cieslak, G Charbonnier, M Tesio, EL Mathieu, M Belhocine, A Touzart, ...
Journal of Experimental Medicine 217 (9), e20192360, 2020
252020
Epigenetic analysis of patients with T-ALL identifies poor outcomes and a hypomethylating agent-responsive subgroup
A Touzart, A Mayakonda, C Smith, J Hey, R Toth, A Cieslak, GP Andrieu, ...
Science translational medicine 13 (595), eabc4834, 2021
212021
Inflammatory signatures distinguish metabolic health in African American women with obesity
GV Denis, P Sebastiani, KA Bertrand, KJ Strissel, AH Tran, J Slama, ...
PLoS One 13 (5), e0196755, 2018
202018
The surgical management and outcome of congenital mediastinal malformations
Q Ballouhey, P Galinier, O Abbo, G Andrieu, C Baunin, A Sartor, JL Rittié, ...
Interactive cardiovascular and thoracic surgery 14 (6), 754-759, 2012
182012
Oncogenetic landscape and clinical impact of IDH1 and IDH2 mutations in T-ALL
M Simonin, A Schmidt, C Bontoux, MÉ Dourthe, E Lengliné, GP Andrieu, ...
Journal of hematology & oncology 14 (1), 74, 2021
152021
Gem GTPase acts upstream Gmip/RhoA to regulate cortical actin remodeling and spindle positioning during early mitosis
G Andrieu, M Quaranta, C Leprince, O Cuvillier, A Hatzoglou
Carcinogenesis 35 (11), 2503-2511, 2014
142014
Relationships among obesity, type 2 diabetes, and plasma cytokines in African American women
GV Denis, P Sebastiani, G Andrieu, AH Tran, KJ Strissel, FL Lombardi, ...
Obesity 25 (11), 1916-1920, 2017
132017
Adenylate kinase 2 expression and addiction in T-ALL
N Maslah, M Latiri, V Asnafi, M Féroul, N Bedjaoui, T Steimlé, E Six, ...
Blood advances 5 (3), 700-710, 2021
112021
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Artiklar 1–20