Clinical trials for BET inhibitors run ahead of the science G Andrieu, AC Belkina, GV Denis Drug Discovery Today: Technologies 19, 45-50, 2016 | 260 | 2016 |
BRD4 regulates breast cancer dissemination through Jagged1/Notch1 signaling G Andrieu, AH Tran, KJ Strissel, GV Denis Cancer research 76 (22), 6555-6567, 2016 | 127 | 2016 |
Osteoblast-derived sphingosine 1-phosphate to induce proliferation and confer resistance to therapeutics to bone metastasis-derived prostate cancer cells L Brizuela, C Martin, P Jeannot, I Ader, C Gstalder, G Andrieu, M Bocquet, ... Molecular oncology 8 (7), 1181-1195, 2014 | 78 | 2014 |
BET proteins exhibit transcriptional and functional opposition in the epithelial-to-mesenchymal transition GP Andrieu, GV Denis Molecular Cancer Research 16 (4), 580-586, 2018 | 55 | 2018 |
BRD4 regulates metastatic potential of castration-resistant prostate cancer through AHNAK JS Shafran, GP Andrieu, B Györffy, GV Denis Molecular Cancer Research 17 (8), 1627-1638, 2019 | 47 | 2019 |
BET protein targeting suppresses the PD-1/PD-L1 pathway in triple-negative breast cancer and elicits anti-tumor immune response GP Andrieu, JS Shafran, CL Smith, AC Belkina, AN Casey, N Jafari, ... Cancer letters 465, 45-58, 2019 | 46 | 2019 |
Neutralizing S1P inhibits intratumoral hypoxia, induces vascular remodelling and sensitizes to chemotherapy in prostate cancer I Ader, C Gstalder, P Bouquerel, M Golzio, G Andrieu, S Zalvidea, ... Oncotarget 6 (15), 13803, 2015 | 43 | 2015 |
Sphingosine 1-phosphate signaling through its receptor S1P5 promotes chromosome segregation and mitotic progression G Andrieu, A Ledoux, S Branka, M Bocquet, J Gilhodes, T Walzer, ... Science signaling 10 (472), eaah4007, 2017 | 42 | 2017 |
BET proteins in abnormal metabolism, inflammation, and the breast cancer microenvironment GP Andrieu, JS Shafran, JT Deeney, KR Bharadwaj, A Rangarajan, ... Journal of leukocyte biology 104 (2), 265-274, 2018 | 40 | 2018 |
BET bromodomain proteins and epigenetic regulation of inflammation: implications for type 2 diabetes and breast cancer DA Nicholas, G Andrieu, KJ Strissel, BS Nikolajczyk, GV Denis Cellular and Molecular Life Sciences 74, 231-243, 2017 | 33 | 2017 |
PRC2 loss of function confers a targetable vulnerability to BET proteins in T-ALL GP Andrieu, M Kohn, M Simonin, CL Smith, A Cieslak, MÉ Dourthe, ... Blood, The Journal of the American Society of Hematology 138 (19), 1855-1869, 2021 | 26 | 2021 |
The GTPase Gem and its partner Kif9 are required for chromosome alignment, spindle length control, and mitotic progression G Andrieu, M Quaranta, C Leprince, A Hatzoglou The FASEB Journal 26 (12), 5025-5034, 2012 | 26 | 2012 |
Blueprint of human thymopoiesis reveals molecular mechanisms of stage-specific TCR enhancer activation A Cieslak, G Charbonnier, M Tesio, EL Mathieu, M Belhocine, A Touzart, ... Journal of Experimental Medicine 217 (9), e20192360, 2020 | 25 | 2020 |
Epigenetic analysis of patients with T-ALL identifies poor outcomes and a hypomethylating agent-responsive subgroup A Touzart, A Mayakonda, C Smith, J Hey, R Toth, A Cieslak, GP Andrieu, ... Science translational medicine 13 (595), eabc4834, 2021 | 21 | 2021 |
Inflammatory signatures distinguish metabolic health in African American women with obesity GV Denis, P Sebastiani, KA Bertrand, KJ Strissel, AH Tran, J Slama, ... PLoS One 13 (5), e0196755, 2018 | 20 | 2018 |
The surgical management and outcome of congenital mediastinal malformations Q Ballouhey, P Galinier, O Abbo, G Andrieu, C Baunin, A Sartor, JL Rittié, ... Interactive cardiovascular and thoracic surgery 14 (6), 754-759, 2012 | 18 | 2012 |
Oncogenetic landscape and clinical impact of IDH1 and IDH2 mutations in T-ALL M Simonin, A Schmidt, C Bontoux, MÉ Dourthe, E Lengliné, GP Andrieu, ... Journal of hematology & oncology 14 (1), 74, 2021 | 15 | 2021 |
Gem GTPase acts upstream Gmip/RhoA to regulate cortical actin remodeling and spindle positioning during early mitosis G Andrieu, M Quaranta, C Leprince, O Cuvillier, A Hatzoglou Carcinogenesis 35 (11), 2503-2511, 2014 | 14 | 2014 |
Relationships among obesity, type 2 diabetes, and plasma cytokines in African American women GV Denis, P Sebastiani, G Andrieu, AH Tran, KJ Strissel, FL Lombardi, ... Obesity 25 (11), 1916-1920, 2017 | 13 | 2017 |
Adenylate kinase 2 expression and addiction in T-ALL N Maslah, M Latiri, V Asnafi, M Féroul, N Bedjaoui, T Steimlé, E Six, ... Blood advances 5 (3), 700-710, 2021 | 11 | 2021 |