Single-cell transcriptome profiling of human pancreatic islets in health and type 2 diabetes Å Segerstolpe, A Palasantza, P Eliasson, EM Andersson, AC Andréasson, ... Cell metabolism 24 (4), 593-607, 2016 | 1314 | 2016 |
Drug screening in human PSC-cardiac organoids identifies pro-proliferative compounds acting via the mevalonate pathway RJ Mills, BL Parker, GA Quaife-Ryan, HK Voges, EJ Needham, A Bornot, ... Cell stem cell 24 (6), 895-907. e6, 2019 | 239 | 2019 |
Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation AR Clausen, SA Lujan, AB Burkholder, CD Orebaugh, JS Williams, ... Nature structural & molecular biology 22 (3), 185-191, 2015 | 197 | 2015 |
The lung environment controls alveolar macrophage metabolism and responsiveness in type 2 inflammation FR Svedberg, SL Brown, MZ Krauss, L Campbell, C Sharpe, M Clausen, ... Nature immunology 20 (5), 571-580, 2019 | 169 | 2019 |
Extracellular vesicles induce minimal hepatotoxicity and immunogenicity AF Saleh, E Lázaro-Ibáñez, MAM Forsgard, O Shatnyeva, X Osteikoetxea, ... Nanoscale 11 (14), 6990-7001, 2019 | 133 | 2019 |
Human iPS-derived astroglia from a stable neural precursor state show improved functionality compared with conventional astrocytic models A Lundin, L Delsing, M Clausen, P Ricchiuto, J Sanchez, A Sabirsh, ... Stem cell reports 10 (3), 1030-1045, 2018 | 105 | 2018 |
Barrier properties and transcriptome expression in human iPSC-derived models of the blood–brain barrier L Delsing, P Dönnes, J Sánchez, M Clausen, D Voulgaris, A Falk, ... Stem cells 36 (12), 1816-1827, 2018 | 100 | 2018 |
Decoding non-random mutational signatures at Cas9 targeted sites A Taheri-Ghahfarokhi, BJM Taylor, R Nitsch, A Lundin, AL Cavallo, ... Nucleic acids research 46 (16), 8417-8434, 2018 | 92 | 2018 |
AMPK activation protects against diet-induced obesity through Ucp1-independent thermogenesis in subcutaneous white adipose tissue AE Pollard, L Martins, PJ Muckett, S Khadayate, A Bornot, M Clausen, ... Nature metabolism 1 (3), 340-349, 2019 | 85 | 2019 |
Modeling human pancreatic beta cell dedifferentiation M Diedisheim, M Oshima, O Albagli, CW Huldt, I Ahlstedt, M Clausen, ... Molecular metabolism 10, 74-86, 2018 | 83 | 2018 |
Therapeutic genome editing with CRISPR/Cas9 in a humanized mouse model ameliorates α1-antitrypsin deficiency phenotype M Bjursell, MJ Porritt, E Ericson, A Taheri-Ghahfarokhi, M Clausen, ... EBioMedicine 29, 104-111, 2018 | 72 | 2018 |
Development of an ObLiGaRe Doxycycline Inducible Cas9 system for pre-clinical cancer drug discovery A Lundin, MJ Porritt, H Jaiswal, F Seeliger, C Johansson, AW Bidar, ... Nature communications 11 (1), 4903, 2020 | 44 | 2020 |
Optimised generation of iPSC-derived macrophages and dendritic cells that are functionally and transcriptionally similar to their primary counterparts S Monkley, JK Krishnaswamy, M Göransson, M Clausen, J Meuller, ... PLoS One 15 (12), e0243807, 2020 | 28 | 2020 |
Single‐cell study of neural stem cells derived from human iPSCs reveals distinct progenitor populations with neurogenic and gliogenic potential M Lam, T Sanosaka, A Lundin, K Imaizumi, D Etal, FH Karlsson, ... Genes to Cells 24 (12), 836-847, 2019 | 22 | 2019 |
Integrative transcriptomic analysis of tissue-specific metabolic crosstalk after myocardial infarction M Arif, M Klevstig, R Benfeitas, S Doran, H Turkez, M Uhlén, M Clausen, ... Elife 10, e66921, 2021 | 20 | 2021 |
Modelling human liver fibrosis in the context of non-alcoholic steatohepatitis using a microphysiological system T Kostrzewski, S Snow, AL Battle, S Peel, Z Ahmad, J Basak, M Surakala, ... Communications Biology 4 (1), 1080, 2021 | 19 | 2021 |
Differential gene expression in human tissue resident regulatory T cells from lung, colon, and blood M Niedzielska, E Israelsson, B Angermann, BS Sidders, M Clausen, ... Oncotarget 9 (90), 36166, 2018 | 17 | 2018 |
Sensitization of the UPR by loss of PPP1R15A promotes fibrosis and senescence in IPF S Monkley, C Overed-Sayer, H Parfrey, D Rassl, D Crowther, ... Scientific Reports 11 (1), 21584, 2021 | 15 | 2021 |
Altered regulation and expression of genes by BET family of proteins in COPD patients R Malhotra, N Kurian, XH Zhou, F Jiang, S Monkley, A DeMicco, ... PLoS One 12 (3), e0173115, 2017 | 12 | 2017 |
hiPS‐Derived Astroglia Model Shows Temporal Transcriptomic Profile Related to Human Neural Development and Glia Competence Acquisition of a Maturing Astrocytic Identity A Lundin, P Ricchiuto, M Clausen, R Hicks, A Falk, A Herland Advanced biosystems 4 (5), 1900226, 2020 | 5 | 2020 |