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Li Che
Li Che
Verified email at ucsf.edu
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A functional mammalian target of rapamycin complex 1 signaling is indispensable for c-Myc-driven hepatocarcinogenesis
L Che, P Liu, M Ge, J Hu, X Li, K Sun, L Cheng, Y Huang, MG Pilo, ...
Hepatology 66 (1), 167–181, 2017
1542017
Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans
L Che, W Chi, Y Qiao, J Zhang, X Song, Y Liu, L Li, J Jia, MG Pilo, J Wang, ...
Gut 69 (1), 177-186, 2020
1462020
Inactivation of fatty acid synthase impairs hepatocarcinogenesis driven by AKT in mice and humans
L LI, GM Pilo, X Li, A Cigliano, G Latte, L Che, C Joseph, M Mela, C Wang, ...
Journal of Hepatology 64 (2), 333-341, 2016
1362016
Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice
L Che, J Hu, L Li, MG Pilo, A Cigliano, S Ribback, X Li, G Latte, M Mela, ...
Scientific Reports, 9;6:20484, 2016
1152016
Differential effects of targeting Notch receptors in a mouse model of liver cancer
EG Huntzicker, K Hötzel, L Choy, L Che, J Ross, G Pau, N Sharma, ...
Hepatology 61 (3), 942–952, 2015
1042015
The mTORC2‐Akt1 cascade is crucial for c‐Myc to promote hepatocarcinogenesis in mice and humans
Z Xu, M Xu, P Liu, S Zhang, R Shang, Y Qiao, L Che, S Ribback, ...
Hepatology 70 (5), 1600-1613, 2019
982019
Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice
S Zhang, X Song, D Cao, Z Xu, B Fan, L Che, J Hu, B Chen, M Dong, ...
Journal of Hepatology, [Epub ahead of print], 2017
962017
Notch2 controls hepatocyte-derived cholangiocarcinoma formation in mice
J Wang, M Dong, Z Xu, X Song, S Zhang, YU Qiao, L Che, J Gordan, K Hu, ...
Oncogene 37 (24), 3229-3242, 2018
932018
Differential Requirement for de novo Lipogenesis in Cholangiocarcinoma and Hepatocellular Carcinoma of Mice and Humans
L Che, L Li, KM Tharp, HM Park, MG Pilo, D Cao, A Cigliano, G Latte, Z Xu, ...
Hepatology 63 (6), 1900-1913, 2016
922016
Glucose catabolism in liver tumors induced by c-MYC can be sustained by various PKM1/PKM2 ratios and pyruvate kinase activities
A Méndez-Lucas, X Li, J Hu, L Che, X Song, J Jia, J Wang, C Xie, ...
Cancer research 77 (16), 4355-4364, 2017
792017
Selections of appropriate regimen of high-dose chemotherapy combined with adoptive cellular therapy with dendritic and cytokine-induced killer cells improved progression-free …
J Ren, L Di, G Song, J Yu, J Jia, Y Zhu, Y Yan, H Jiang, X Liang, L Che, ...
Clinical and Translational Oncology 15 (10), 780-788, 2013
772013
Both de novo synthetized and exogenous fatty acids support the growth of hepatocellular carcinoma cells
D Cao, X Song, L Che, X Li, MG Pilo, G Vidili, A Porcu, A Solinas, ...
Liver International 37 (1), 80–89, 2016
732016
Cabozantinib-based combination therapy for the treatment of hepatocellular carcinoma
R Shang, X Song, P Wang, Y Zhou, X Lu, J Wang, M Xu, X Chen, ...
Gut 70 (9), 1746-1757, 2021
712021
MicroRNA‐206 Prevents the Pathogenesis of Hepatocellular Carcinoma Via Modulating Expression of cMet and Cdk6
H Wu, J Tao, X Li, T Zhang, L Zhao, J Xiong, Z Zeng, N Zhan, L Che, ...
Hepatology, [Epub ahead of print], 2017
712017
Activation of sonic hedgehog signaling pathway is an independent potential prognosis predictor in human hepatocellular carcinoma patients
L Che, Y Yuan, J Jia, J Ren
CHINSES JOURNAL OF CANCER RESEARCH 24 (4), 323–331, 2012
682012
Combined CDK4/6 and pan-mTOR inhibition is synergistic against intrahepatic cholangiocarcinoma
X Song, X Liu, H Wang, J Wang, Y Qiao, A Cigliano, K Utpatel, S Ribback, ...
Clinical Cancer Research 25 (1), 403-413, 2019
662019
Pathogenetic, prognostic, and therapeutic role of fatty acid synthase in human hepatocellular carcinoma
L Che, P Paliogiannis, A Cigliano, MG Pilo, X Chen, DF Calvisi
Frontiers in oncology 9, 1412, 2019
572019
Correlation of exon 3 β-catenin mutations with glutamine synthetase staining patterns in hepatocellular adenoma and hepatocellular carcinoma
G Hale, X Liu, J Hu, Z Xu, L Che, D Solomon, C Tsokos, N Shafizadeh, ...
Modern Pathology 29, 1370–1380, 2016
572016
Oncogene dependent requirement of fatty acid synthase in hepatocellular carcinoma
L Che, MG Pilo, A Cigliano, G Latte, MM Simile, S Ribback, F Dombrowski, ...
Cell Cycle 16 (6), 499-507, 2017
532017
Loss of Fbxw7 synergizes with activated Akt signaling to promote c-Myc dependent cholangiocarcinogenesis
J Wang, H Wang, M Peters, N Ding, S Ribback, K Utpatel, A Cigliano, ...
Journal of hepatology 71 (4), 742-752, 2019
512019
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