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Takayuki TSUKUBA
Takayuki TSUKUBA
Nagasaki University, Graduate School of Biomedical Sciences
Verifierad e-postadress på nagasaki-u.ac.jp - Startsida
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13159*2021
Berberine inhibits RANKL-induced osteoclast formation and survival through suppressing the NF-κB and Akt pathways
JP Hu, K Nishishita, E Sakai, H Yoshida, Y Kato, T Tsukuba, K Okamoto
European journal of pharmacology 580 (1-2), 70-79, 2008
1772008
Suppression of pathogenicity of Porphyromonas gingivalis by newly developed gingipain inhibitors
T Kadowaki, A Baba, N Abe, R Takii, M Hashimoto, T Tsukuba, S Okazaki, ...
Molecular pharmacology 66 (6), 1599-1606, 2004
1392004
Haemoglobin receptor protein is intragenically encoded by the cysteine proteinase‐encoding genes and the haemagglutinin‐encoding gene of Porphyromonas gingivalis
K Nakayama, DB Ratnayake, T Tsukuba, T Kadowaki, K Yamamoto, ...
Molecular microbiology 27 (1), 51-61, 1998
1361998
Increased expression of cathepsins E and D in neurons of the aged rat brain and their colocalization with lipofuscin and carboxy‐terminal fragments of Alzheimer amyloid …
H Nakanishi, T Amano, DF Sastradipura, Y Yoshimine, T Tsukuba, ...
Journal of neurochemistry 68 (2), 739-749, 1997
1201997
Association of cathepsin E deficiency with development of atopic dermatitis
T Tsukuba, K Okamoto, Y Okamoto, M Yanagawa, K Kohmura, Y Yasuda, ...
The journal of biochemistry 134 (6), 893-902, 2003
1092003
Localization of cathepsins B, D, and L in the rat osteoclast by immuno-light and-electron microscopy
T Goto, T Tanaka, T Kiyoshima, R Moroi, T Tsukuba, K Yamamoto, ...
Histochemistry 101, 33-40, 1994
1061994
Immunohistochemical localization of cathepsins B, D and L in the rat osteoclast
T Goto, T Tsukuba, T Kiyoshima, Y Nishimura, K Kato, K Yamamoto, ...
Histochemistry 99, 411-414, 1993
1051993
New functional aspects of cathepsin D and cathepsin E
T Tsukuba, K Okamoto, Y Yasuda, W Morikawa, H Nakanishi, ...
Molecules and cells 10, 601-611, 2000
1032000
Cathepsin E prevents tumor growth and metastasis by catalyzing the proteolytic release of soluble TRAIL from tumor cell surface
T Kawakubo, K Okamoto, J Iwata, M Shin, Y Okamoto, A Yasukochi, ...
Cancer research 67 (22), 10869-10878, 2007
1002007
Identification of cellular compartments involved in processing of cathepsin E in primary cultures of rat microglia
DF Sastradipura, H Nakanishi, T Tsukuba, K Nishishita, H Sakai, Y Kato, ...
Journal of neurochemistry 70 (5), 2045-2056, 1998
961998
A functional virulence complex composed of gingipains, adhesins, and lipopolysaccharide shows high affinity to host cells and matrix proteins and escapes recognition by host …
R Takii, T Kadowaki, A Baba, T Tsukuba, K Yamamoto
Infection and immunity 73 (2), 883-893, 2005
892005
Immunohistochemical localization of cathepsins D and E in human gastric cancer: a possible correlation with local invasive and metastatic activities of carcinoma cells
K Matsuo, I Kobayashi, T Tsukuba, T Kiyoshima, Y Ishibashi, A Miyoshi, ...
Human pathology 27 (2), 184-190, 1996
801996
Transient forebrain ischemia induces increased expression and specific localization of cathepsins E and D in rat hippocampus and neostriatum
H Nakanishi, T Tsukuba, T Kondou, T Tanaka, K Yamamoto
Experimental neurology 121 (2), 215-223, 1993
781993
Cathepsin E deficiency induces a novel form of lysosomal storage disorder showing the accumulation of lysosomal membrane sialoglycoproteins and the elevation of lysosomal pH in …
M Yanagawa, T Tsukuba, T Nishioku, Y Okamoto, K Okamoto, R Takii, ...
Journal of biological chemistry 282 (3), 1851-1862, 2007
752007
Fisetin inhibits osteoclastogenesis through prevention of RANKL-induced ROS production by Nrf2-mediated up-regulation of phase II antioxidant enzymes
E Sakai, M Shimada-Sugawara, Y Yamaguchi, H Sakamoto, R Fumimoto, ...
Journal of pharmacological sciences 121 (4), 288-298, 2013
672013
Role for Gingipains in Porphyromonas gingivalis Traffic to Phagolysosomes and Survival in Human Aortic Endothelial Cells
K Yamatake, M Maeda, T Kadowaki, R Takii, T Tsukuba, T Ueno, ...
Infection and immunity 75 (5), 2090-2100, 2007
662007
Suppression of RANKL‐dependent heme oxygenase‐1 is required for high mobility group box 1 release and osteoclastogenesis
E Sakai, M Shimada‐Sugawara, K Nishishita, Y Fukuma, M Naito, ...
Journal of cellular biochemistry 113 (2), 486-498, 2012
612012
N-Linked oligosaccharides on the meprin A metalloprotease are important for secretion and enzymatic activity, but not for apical targeting
T Kadowaki, T Tsukuba, GP Bertenshaw, JS Bond
Journal of Biological Chemistry 275 (33), 25577-25584, 2000
612000
Rab27A regulates transport of cell surface receptors modulating multinucleation and lysosome-related organelles in osteoclasts
M Shimada-Sugawara, E Sakai, K Okamoto, M Fukuda, T Izumi, ...
Scientific reports 5 (1), 1-11, 2015
602015
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