Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13159* | 2021 |
Berberine inhibits RANKL-induced osteoclast formation and survival through suppressing the NF-κB and Akt pathways JP Hu, K Nishishita, E Sakai, H Yoshida, Y Kato, T Tsukuba, K Okamoto European journal of pharmacology 580 (1-2), 70-79, 2008 | 177 | 2008 |
Suppression of pathogenicity of Porphyromonas gingivalis by newly developed gingipain inhibitors T Kadowaki, A Baba, N Abe, R Takii, M Hashimoto, T Tsukuba, S Okazaki, ... Molecular pharmacology 66 (6), 1599-1606, 2004 | 139 | 2004 |
Haemoglobin receptor protein is intragenically encoded by the cysteine proteinase‐encoding genes and the haemagglutinin‐encoding gene of Porphyromonas gingivalis K Nakayama, DB Ratnayake, T Tsukuba, T Kadowaki, K Yamamoto, ... Molecular microbiology 27 (1), 51-61, 1998 | 136 | 1998 |
Increased expression of cathepsins E and D in neurons of the aged rat brain and their colocalization with lipofuscin and carboxy‐terminal fragments of Alzheimer amyloid … H Nakanishi, T Amano, DF Sastradipura, Y Yoshimine, T Tsukuba, ... Journal of neurochemistry 68 (2), 739-749, 1997 | 120 | 1997 |
Association of cathepsin E deficiency with development of atopic dermatitis T Tsukuba, K Okamoto, Y Okamoto, M Yanagawa, K Kohmura, Y Yasuda, ... The journal of biochemistry 134 (6), 893-902, 2003 | 109 | 2003 |
Localization of cathepsins B, D, and L in the rat osteoclast by immuno-light and-electron microscopy T Goto, T Tanaka, T Kiyoshima, R Moroi, T Tsukuba, K Yamamoto, ... Histochemistry 101, 33-40, 1994 | 106 | 1994 |
Immunohistochemical localization of cathepsins B, D and L in the rat osteoclast T Goto, T Tsukuba, T Kiyoshima, Y Nishimura, K Kato, K Yamamoto, ... Histochemistry 99, 411-414, 1993 | 105 | 1993 |
New functional aspects of cathepsin D and cathepsin E T Tsukuba, K Okamoto, Y Yasuda, W Morikawa, H Nakanishi, ... Molecules and cells 10, 601-611, 2000 | 103 | 2000 |
Cathepsin E prevents tumor growth and metastasis by catalyzing the proteolytic release of soluble TRAIL from tumor cell surface T Kawakubo, K Okamoto, J Iwata, M Shin, Y Okamoto, A Yasukochi, ... Cancer research 67 (22), 10869-10878, 2007 | 100 | 2007 |
Identification of cellular compartments involved in processing of cathepsin E in primary cultures of rat microglia DF Sastradipura, H Nakanishi, T Tsukuba, K Nishishita, H Sakai, Y Kato, ... Journal of neurochemistry 70 (5), 2045-2056, 1998 | 96 | 1998 |
A functional virulence complex composed of gingipains, adhesins, and lipopolysaccharide shows high affinity to host cells and matrix proteins and escapes recognition by host … R Takii, T Kadowaki, A Baba, T Tsukuba, K Yamamoto Infection and immunity 73 (2), 883-893, 2005 | 89 | 2005 |
Immunohistochemical localization of cathepsins D and E in human gastric cancer: a possible correlation with local invasive and metastatic activities of carcinoma cells K Matsuo, I Kobayashi, T Tsukuba, T Kiyoshima, Y Ishibashi, A Miyoshi, ... Human pathology 27 (2), 184-190, 1996 | 80 | 1996 |
Transient forebrain ischemia induces increased expression and specific localization of cathepsins E and D in rat hippocampus and neostriatum H Nakanishi, T Tsukuba, T Kondou, T Tanaka, K Yamamoto Experimental neurology 121 (2), 215-223, 1993 | 78 | 1993 |
Cathepsin E deficiency induces a novel form of lysosomal storage disorder showing the accumulation of lysosomal membrane sialoglycoproteins and the elevation of lysosomal pH in … M Yanagawa, T Tsukuba, T Nishioku, Y Okamoto, K Okamoto, R Takii, ... Journal of biological chemistry 282 (3), 1851-1862, 2007 | 75 | 2007 |
Fisetin inhibits osteoclastogenesis through prevention of RANKL-induced ROS production by Nrf2-mediated up-regulation of phase II antioxidant enzymes E Sakai, M Shimada-Sugawara, Y Yamaguchi, H Sakamoto, R Fumimoto, ... Journal of pharmacological sciences 121 (4), 288-298, 2013 | 67 | 2013 |
Role for Gingipains in Porphyromonas gingivalis Traffic to Phagolysosomes and Survival in Human Aortic Endothelial Cells K Yamatake, M Maeda, T Kadowaki, R Takii, T Tsukuba, T Ueno, ... Infection and immunity 75 (5), 2090-2100, 2007 | 66 | 2007 |
Suppression of RANKL‐dependent heme oxygenase‐1 is required for high mobility group box 1 release and osteoclastogenesis E Sakai, M Shimada‐Sugawara, K Nishishita, Y Fukuma, M Naito, ... Journal of cellular biochemistry 113 (2), 486-498, 2012 | 61 | 2012 |
N-Linked oligosaccharides on the meprin A metalloprotease are important for secretion and enzymatic activity, but not for apical targeting T Kadowaki, T Tsukuba, GP Bertenshaw, JS Bond Journal of Biological Chemistry 275 (33), 25577-25584, 2000 | 61 | 2000 |
Rab27A regulates transport of cell surface receptors modulating multinucleation and lysosome-related organelles in osteoclasts M Shimada-Sugawara, E Sakai, K Okamoto, M Fukuda, T Izumi, ... Scientific reports 5 (1), 1-11, 2015 | 60 | 2015 |