| Predictable and precise template-free CRISPR editing of pathogenic variants MW Shen, M Arbab, JY Hsu, D Worstell, SJ Culbertson, O Krabbe, ... Nature 563 (7733), 646-651, 2018 | 501 | 2018 |
| Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions AC Fahed, M Wang, JR Homburger, AP Patel, AG Bick, CL Neben, C Lai, ... Nature communications 11 (1), 3635, 2020 | 325 | 2020 |
| Heterogeneous nucleation of ice in (NH4)2SO4‐H2O particles with mineral dust immersions B Zuberi, AK Bertram, CA Cassa, LT Molina, MJ Molina Geophysical research letters 29 (10), 142-1-142-4, 2002 | 210 | 2002 |
| Determinants of base editing outcomes from target library analysis and machine learning M Arbab, MW Shen, B Mok, C Wilson, Ż Matuszek, CA Cassa, DR Liu Cell 182 (2), 463-480. e30, 2020 | 204 | 2020 |
| Twitter as a sentinel in emergency situations: lessons from the Boston marathon explosions CA Cassa, R Chunara, K Mandl, JS Brownstein PLoS currents 5, 2013 | 169 | 2013 |
| Estimating the selective effects of heterozygous protein-truncating variants from human exome data CA Cassa, D Weghorn, DJ Balick, DM Jordan, D Nusinow, KE Samocha, ... Nature genetics 49 (5), 806-810, 2017 | 151 | 2017 |
| Privacy protection versus cluster detection in spatial epidemiology KL Olson, SJ Grannis, KD Mandl American Journal of Public Health 96 (11), 2002-2008, 2006 | 121 | 2006 |
| An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge CA Brownstein, AH Beggs, N Homer, B Merriman, TW Yu, KC Flannery, ... Genome biology 15, 1-18, 2014 | 119 | 2014 |
| A context-sensitive approach to anonymizing spatial surveillance data: impact on outbreak detection CA Cassa, SJ Grannis, JM Overhage, KD Mandl Journal of the American Medical Informatics Association 13 (2), 160-165, 2006 | 112 | 2006 |
| Identification of cis-suppression of human disease mutations by comparative genomics DM Jordan, SG Frangakis, C Golzio, CA Cassa, J Kurtzberg, ... Nature 524 (7564), 225-229, 2015 | 111 | 2015 |
| Disclosing pathogenic genetic variants to research participants: quantifying an emerging ethical responsibility CA Cassa, SK Savage, PL Taylor, RC Green, AL McGuire, KD Mandl Genome research 22 (3), 421-428, 2012 | 106 | 2012 |
| Large numbers of genetic variants considered to be pathogenic are common in asymptomatic individuals CA Cassa, MY Tong, DM Jordan Human mutation 34 (9), 1216-1220, 2013 | 103 | 2013 |
| No place to hide—reverse identification of patients from published maps JS Brownstein, CA Cassa, KD Mandl New England Journal of Medicine 355 (16), 1741-1742, 2006 | 103 | 2006 |
| Association of rare pathogenic DNA variants for familial hypercholesterolemia, hereditary breast and ovarian cancer syndrome, and lynch syndrome with disease risk in adults … AP Patel, M Wang, AC Fahed, H Mason-Suares, D Brockman, R Pelletier, ... JAMA network open 3 (4), e203959-e203959, 2020 | 82 | 2020 |
| Dominance of deleterious alleles controls the response to a population bottleneck DJ Balick, R Do, CA Cassa, D Reich, SR Sunyaev PLoS genetics 11 (8), e1005436, 2015 | 79 | 2015 |
| Revealing the spatial distribution of a disease while preserving privacy SC Wieland, CA Cassa, KD Mandl, B Berger Proceedings of the National Academy of Sciences 105 (46), 17608-17613, 2008 | 79 | 2008 |
| Measuring outbreak-detection performance by using controlled feature set simulations. KD Mandl, B Reis, C Cassa MMWR: Morbidity & Mortality Weekly Report 53, 2004 | 76 | 2004 |
| The missing link between genetic association and regulatory function NJ Connally, S Nazeen, D Lee, H Shi, J Stamatoyannopoulos, S Chun, ... Elife 11, e74970, 2022 | 59 | 2022 |
| The role of epistasis in protein evolution DM McCandlish, E Rajon, P Shah, Y Ding, JB Plotkin Nature 497 (7451), E1-E2, 2013 | 57 | 2013 |
| An unsupervised classification method for inferring original case locations from low-resolution disease maps JS Brownstein, CA Cassa, IS Kohane, KD Mandl International Journal of Health Geographics 5, 1-7, 2006 | 56 | 2006 |
