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James Schaeffer
James Schaeffer
Genesis Therapeutics
Verifierad e-postadress på genesistherapeutics.ai - Startsida
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A receptor in pituitary and hypothalamus that functions in growth hormone release
AD Howard, SD Feighner, DF Cully, JP Arena, PA Liberator, ...
Science 273 (5277), 974-977, 1996
26491996
Immunolocalization of estrogen receptor β in the mouse brain: comparison with estrogen receptor α
SW Mitra, E Hoskin, J Yudkovitz, L Pear, HA Wilkinson, S Hayashi, ...
Endocrinology 144 (5), 2055-2067, 2003
9912003
Cloning of an avermectin-sensitive glutamate-gated chloride channel from Caenorhabditis elegans
DF Cully, DK Vassilatis, KK Liu, PS Paress, LHT Van der Ploeg, ...
Nature 371 (6499), 707-711, 1994
8851994
Regulation of vascular endothelial growth factor-dependent retinal neovascularization by insulin-like growth factor-1 receptor
LEH Smith, W Shen, C Perruzzi, S Soker, F Kinose, X Xu, G Robinson, ...
Nature medicine 5 (12), 1390-1395, 1999
7521999
Rapid identification of subtype-selective agonists of the somatostatin receptor through combinatorial chemistry
SP Rohrer, ET Birzin, RT Mosley, SC Berk, SM Hutchins, DM Shen, ...
Science 282 (5389), 737-740, 1998
5671998
Essential role of growth hormone in ischemia-induced retinal neovascularization
LEH Smith, JJ Kopchick, W Chen, J Knapp, F Kinose, D Daley, E Foley, ...
Science 276 (5319), 1706-1709, 1997
5301997
11β-HSD1 inhibition ameliorates metabolic syndrome and prevents progression of atherosclerosis in mice
A Hermanowski-Vosatka, JM Balkovec, K Cheng, HY Chen, M Hernandez, ...
The Journal of Experimental Medicine 202 (4), 517-527, 2005
4992005
Somatostatin Inhibits Insulin and Glucagon Secretion via Two Receptor Subtypes: An in Vitro Study of Pancreatic Islets from Somatostatin Receptor 2 Knockout Mice
MZ Strowski, RM Parmar, AD Blake, JM Schaeffer
Endocrinology 141 (1), 111-117, 2000
4272000
Identification of a Drosophila melanogaster glutamate-gated chloride channel sensitive to the antiparasitic agent avermectin
DF Cully, PS Paress, KK Liu, JM Schaeffer, JP Arena
Journal of Biological Chemistry 271 (33), 20187-20191, 1996
3301996
The mechanism of action of avermectins in Caenorhabditis elegans: correlation between activation of glutamate-sensitive chloride current, membrane binding, and biological activity
JP Arena, KK Liu, PS Paress, EG Frazier, DF Cully, H Mrozik, ...
The Journal of parasitology, 286-294, 1995
3111995
Mode of action of ivermectin
MJ Turner, JM Schaeffer
Ivermectin and abamectin, 73-88, 1989
2721989
Nuclear receptors have distinct affinities for coactivators: characterization by fluorescence resonance energy transfer
G Zhou, R Cummings, Y Li, S Mitra, HA Wilkinson, A Elbrecht, JD Hermes, ...
Molecular endocrinology 12 (10), 1594-1604, 1998
2451998
17β-estradiol-induced antidepressant-like effect in the forced swim test is absent in estrogen receptor-β knockout (BERKO) mice
BA Rocha, R Fleischer, JM Schaeffer, SP Rohrer, GJ Hickey
Psychopharmacology 179, 637-643, 2005
2322005
Expression of a glutamate-activated chloride current in Xenopus oocytes injected with Caenorhabditis elegans RNA: evidence for modulation by avermectin
JP Arena, KK Liu, PS Paress, JM Schaeffer, DF Cully
Molecular Brain Research 15 (3-4), 339-348, 1992
1991992
Somatostatin receptor subtype 2 knockout mice are refractory to growth hormone-negative feedback on arcuate neurons
H Zheng, A Bailey, MH Jiang, K Honda, HY Chen, ME Trumbauer, ...
Molecular Endocrinology 11 (11), 1709-1717, 1997
1961997
Synthesis and biological activities of potent peptidomimetics selective for somatostatin receptor subtype 2
L Yang, SC Berk, SP Rohrer, RT Mosley, L Guo, DJ Underwood, ...
Proceedings of the National Academy of Sciences 95 (18), 10836-10841, 1998
1781998
Somatostatin receptor subtype 5 regulates insulin secretion and glucose homeostasis
MZ Strowski, M Kohler, HY Chen, ME Trumbauer, Z Li, D Szalkowski, ...
Molecular Endocrinology 17 (1), 93-106, 2003
1582003
Avermectin binding in Caenorhabditis elegans: a two-state model for the avermectin binding site
JM Schaeffer, HW Haines
Biochemical pharmacology 38 (14), 2329-2338, 1989
1581989
Genetic and biochemical evidence for a novel avermectin-sensitive chloride channel in Caenorhabditis elegans: isolation and characterization
DK Vassilatis, JP Arena, RHA Plasterk, HA Wilkinson, JM Schaeffer, ...
Journal of Biological Chemistry 272 (52), 33167-33174, 1997
1561997
High basal gastric acid secretion in somatostatin receptor subtype 2 knockout mice
V Martinez, AP Curi, B Torkian, JM Schaeffer, HA Wilkinson, JH Walsh, ...
Gastroenterology 114 (6), 1125-1132, 1998
1501998
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