| Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing L Rasche, SS Chavan, OW Stephens, PH Patel, R Tytarenko, C Ashby, ... Nature communications 8 (1), 268, 2017 | 352 | 2017 |
| Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma N Weinhold, C Ashby, L Rasche, SS Chavan, C Stein, OW Stephens, ... Blood, The Journal of the American Society of Hematology 128 (13), 1735-1744, 2016 | 216 | 2016 |
| The presence of large focal lesions is a strong independent prognostic factor in multiple myeloma L Rasche, EJ Angtuaco, TL Alpe, GH Gershner, JE McDonald, RS Samant, ... Blood, The Journal of the American Society of Hematology 132 (1), 59-66, 2018 | 92 | 2018 |
| The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma EM Boyle, S Deshpande, R Tytarenko, C Ashby, Y Wang, MA Bauer, ... Nature communications 12 (1), 293, 2021 | 79 | 2021 |
| Bi-allelic inactivation is more prevalent at relapse in multiple myeloma, identifying RB1 as an independent prognostic marker SS Chavan, J He, R Tytarenko, S Deshpande, P Patel, M Bailey, CK Stein, ... Blood cancer journal 7 (2), e535-e535, 2017 | 71 | 2017 |
| Expression of functional aromatase in the epididymis: role of androgens and LH in modulation of expression and activity D Shayu, AJ Rao Molecular and cellular endocrinology 249 (1-2), 40-50, 2006 | 61 | 2006 |
| Microhomology-mediated end joining drives complex rearrangements and overexpression of MYC and PVT1 in multiple myeloma A Mikulasova, C Ashby, RG Tytarenko, P Qu, A Rosenthal, JA Dent, ... Haematologica 105 (4), 1055, 2020 | 53 | 2020 |
| BRAF and DIS3 mutations associate with adverse outcome in a long-term follow-up of patients with multiple myeloma EM Boyle, C Ashby, RG Tytarenko, S Deshpande, H Wang, Y Wang, ... Clinical Cancer Research 26 (10), 2422-2432, 2020 | 47 | 2020 |
| Loss of heterozygosity as a marker of homologous repair deficiency in multiple myeloma: a role for PARP inhibition? C Pawlyn, A Loehr, C Ashby, R Tytarenko, S Deshpande, J Sun, ... Leukemia 32 (7), 1561-1566, 2018 | 45 | 2018 |
| Effects of ICI 182780 on estrogen receptor expression, fluid absorption and sperm motility in the epididymis of the bonnet monkey D Shayu, CS ChennaKesava, R Soundarajan, AJ Rao Reproductive Biology and Endocrinology 3, 1-15, 2005 | 42 | 2005 |
| Imatinib resistance and microcytic erythrocytosis in a KitV558Δ; T669I/+ gatekeeper-mutant mouse model of gastrointestinal stromal tumor B Bosbach, S Deshpande, F Rossi, JH Shieh, G Sommer, E de Stanchina, ... Proceedings of the National Academy of Sciences 109 (34), E2276-E2283, 2012 | 35 | 2012 |
| Genomic analysis of primary plasma cell leukemia reveals complex structural alterations and high-risk mutational patterns C Schinke, EM Boyle, C Ashby, Y Wang, V Lyzogubov, C Wardell, P Qu, ... Blood cancer journal 10 (6), 70, 2020 | 33 | 2020 |
| Kinase domain activation through gene rearrangement in multiple myeloma GJ Morgan, J He, R Tytarenko, P Patel, OW Stephens, S Zhong, ... Leukemia 32 (11), 2435-2444, 2018 | 29 | 2018 |
| Characterizing the role of the immune microenvironment in multiple myeloma progression at a single-cell level C Schinke, AM Poos, M Bauer, L John, S Johnson, S Deshpande, ... Blood Advances 6 (22), 5873-5883, 2022 | 28 | 2022 |
| The prognostic value of the depth of response in multiple myeloma depends on the time of assessment, risk status and molecular subtype C Schinke, A Hoering, H Wang, V Carlton, S Thanandrarajan, ... Haematologica 102 (8), e313, 2017 | 28 | 2017 |
| The spatio-temporal evolution of multiple myeloma from baseline to relapse-refractory states L Rasche, C Schinke, F Maura, MA Bauer, C Ashby, S Deshpande, ... Nature Communications 13 (1), 4517, 2022 | 25 | 2022 |
| Monitoring treatment response and disease progression in myeloma with circulating cell‐free DNA S Deshpande, RG Tytarenko, Y Wang, EM Boyle, C Ashby, CD Schinke, ... European Journal of Haematology 106 (2), 230-240, 2021 | 25 | 2021 |
| The functional epigenetic landscape of aberrant gene expression in molecular subgroups of newly diagnosed multiple myeloma SR Choudhury, C Ashby, R Tytarenko, M Bauer, Y Wang, S Deshpande, ... Journal of hematology & oncology 13, 1-15, 2020 | 21 | 2020 |
| KIT receptor gain-of-function in hematopoiesis enhances stem cell self-renewal and promotes progenitor cell expansion S Deshpande, B Bosbach, Y Yozgat, CY Park, MAS Moore, P Besmer Stem Cells 31 (8), 1683-1695, 2013 | 20 | 2013 |
| Kit ligand cytoplasmic domain is essential for basolateral sorting in vivo and has roles in spermatogenesis and hematopoiesis S Deshpande, V Agosti, K Manova, MAS Moore, MP Hardy, P Besmer Developmental biology 337 (2), 199-210, 2010 | 19 | 2010 |
