| Cellular immunostimulation by CpG-sequence-coated DNA origami structures VJ Schuller, S Heidegger, N Sandholzer, PC Nickels, NA Suhartha, ... ACS nano 5 (12), 9696-9702, 2011 | 518 | 2011 |
| RIG-I/MAVS and STING signaling promote gut integrity during irradiation-and immune-mediated tissue injury JC Fischer, M Bscheider, G Eisenkolb, CC Lin, A Wintges, V Otten, ... Science translational medicine 9 (386), eaag2513, 2017 | 128 | 2017 |
| RIG-I activation is critical for responsiveness to checkpoint blockade S Heidegger, A Wintges, F Stritzke, S Bek, K Steiger, PA Koenig, S Göttert, ... Science Immunology 4 (39), eaau8943, 2019 | 125 | 2019 |
| Immune response to functionalized mesoporous silica nanoparticles for targeted drug delivery S Heidegger, D Gößl, A Schmidt, S Niedermayer, C Argyo, S Endres, ... Nanoscale 8 (2), 938-948, 2016 | 115 | 2016 |
| Systemic cancer therapy with a small molecule agonist of toll-like receptor 7 can be improved by circumventing TLR tolerance C Bourquin, C Hotz, D Noerenberg, A Voelkl, S Heidegger, LC Roetzer, ... Cancer research 71 (15), 5123-5133, 2011 | 99 | 2011 |
| The role of pattern-recognition receptors in graft-versus-host disease and graft-versus-leukemia after allogeneic stem cell transplantation S Heidegger, MRM van den Brink, T Haas, H Poeck Frontiers in immunology 5, 337, 2014 | 94 | 2014 |
| Interleukin-22 is frequently expressed in small-and large-cell lung cancer and promotes growth in chemotherapy-resistant cancer cells S Kobold, S Völk, T Clauditz, NJ Küpper, S Minner, A Tufman, P Düwell, ... Journal of Thoracic Oncology 8 (8), 1032-1042, 2013 | 86 | 2013 |
| RIG-I activating immunostimulatory RNA boosts the efficacy of anticancer vaccines and synergizes with immune checkpoint blockade S Heidegger, D Kreppel, M Bscheider, F Stritzke, T Nedelko, A Wintges, ... EBioMedicine 41, 146-155, 2019 | 47 | 2019 |
| A20 restrains thymic regulatory T cell development JC Fischer, V Otten, M Kober, C Drees, M Rosenbaum, M Schmickl, ... The Journal of Immunology 199 (7), 2356-2365, 2017 | 44 | 2017 |
| Delivery of immunostimulatory RNA oligonucleotides by gelatin nanoparticles triggers an efficient antitumoral response C Bourquin, C Wurzenberger, S Heidegger, S Fuchs, D Anz, S Weigel, ... Journal of immunotherapy 33 (9), 935-944, 2010 | 40 | 2010 |
| TLR and RLR signaling are reprogrammed in opposite directions after detection of viral infection C Hotz, LC Roetzer, T Huber, A Sailer, A Oberson, M Treinies, ... The Journal of Immunology 195 (9), 4387-4395, 2015 | 39 | 2015 |
| Targeting intrinsic RIG-I signaling turns melanoma cells into type I interferon-releasing cellular antitumor vaccines S Bek, F Stritzke, A Wintges, T Nedelko, DFR Böhmer, JC Fischer, T Haas, ... Oncoimmunology 8 (4), e1570779, 2019 | 32 | 2019 |
| Card9 controls Dectin‐1‐induced T‐cell cytotoxicity and tumor growth in mice T Haas, S Heidegger, A Wintges, M Bscheider, S Bek, JC Fischer, ... European Journal of Immunology 47 (5), 872-879, 2017 | 32 | 2017 |
| The microbial metabolite desaminotyrosine enhances T-cell priming and cancer immunotherapy with immune checkpoint inhibitors L Joachim, S Göttert, A Sax, K Steiger, K Neuhaus, P Heinrich, K Fan, ... EBioMedicine 97, 2023 | 14 | 2023 |
| Type I interferon signaling before hematopoietic stem cell transplantation lowers donor T cell activation via reduced allogenicity of recipient cells JC Fischer, M Bscheider, S Göttert, E Thiele Orberg, SE Combs, ... Scientific Reports 9 (1), 14955, 2019 | 14 | 2019 |
| Bacteria and bacteriophage consortia are associated with protective intestinal metabolites in patients receiving stem cell transplantation E Thiele Orberg, E Meedt, A Hiergeist, J Xue, P Heinrich, J Ru, S Ghimire, ... Nature Cancer 5 (1), 187-208, 2024 | 13 | 2024 |
| Innate immune stimulation in cancer therapy P Düwell, S Heidegger, S Kobold Hematology/Oncology Clinics 33 (2), 215-231, 2019 | 12 | 2019 |
| Combination therapy with brentuximab vedotin and cisplatin/cytarabine in a patient with primarily refractory anaplastic lymphoma kinase positive anaplastic large cell lymphoma S Heidegger, AJ Beer, E Geissinger, A Rosenwald, C Peschel, ... OncoTargets and therapy, 1123-1127, 2014 | 12 | 2014 |
| Mycoplasma hyorhinis-Contaminated Cell Lines Activate Primary Innate Immune Cells via a Protease-Sensitive Factor S Heidegger, A Jarosch, M Schmickl, S Endres, C Bourquin, C Hotz PloS one 10 (11), e0142523, 2015 | 11 | 2015 |
| Negative feedback regulation of MAPK signaling is an important driver of chronic lymphocytic leukemia progression V Ecker, L Brandmeier, M Stumpf, P Giansanti, AV Moreira, L Pfeuffer, ... Cell reports 42 (10), 2023 | 10 | 2023 |
