Simon Heidegger
Simon Heidegger
Physician Scientist, Klinikum rechts der Isar, Technical University Munich
Verified email at
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Cellular immunostimulation by CpG-sequence-coated DNA origami structures
VJ Schuller, S Heidegger, N Sandholzer, PC Nickels, NA Suhartha, ...
ACS nano 5 (12), 9696-9702, 2011
RIG-I/MAVS and STING signaling promote gut integrity during irradiation-and immune-mediated tissue injury
JC Fischer, M Bscheider, G Eisenkolb, CC Lin, A Wintges, V Otten, ...
Science translational medicine 9 (386), eaag2513, 2017
RIG-I activation is critical for responsiveness to checkpoint blockade
S Heidegger, A Wintges, F Stritzke, S Bek, K Steiger, PA Koenig, S Göttert, ...
Science Immunology 4 (39), eaau8943, 2019
Immune response to functionalized mesoporous silica nanoparticles for targeted drug delivery
S Heidegger, D Gößl, A Schmidt, S Niedermayer, C Argyo, S Endres, ...
Nanoscale 8 (2), 938-948, 2016
Systemic cancer therapy with a small molecule agonist of toll-like receptor 7 can be improved by circumventing TLR tolerance
C Bourquin, C Hotz, D Noerenberg, A Voelkl, S Heidegger, LC Roetzer, ...
Cancer research 71 (15), 5123-5133, 2011
The role of pattern-recognition receptors in graft-versus-host disease and graft-versus-leukemia after allogeneic stem cell transplantation
S Heidegger, MRM van den Brink, T Haas, H Poeck
Frontiers in immunology 5, 96047, 2014
Interleukin-22 is frequently expressed in small-and large-cell lung cancer and promotes growth in chemotherapy-resistant cancer cells
S Kobold, S Völk, T Clauditz, NJ Küpper, S Minner, A Tufman, P Düwell, ...
Journal of Thoracic Oncology 8 (8), 1032-1042, 2013
RIG-I activating immunostimulatory RNA boosts the efficacy of anticancer vaccines and synergizes with immune checkpoint blockade
S Heidegger, D Kreppel, M Bscheider, F Stritzke, T Nedelko, A Wintges, ...
EBioMedicine 41, 146-155, 2019
A20 restrains thymic regulatory T cell development
JC Fischer, V Otten, M Kober, C Drees, M Rosenbaum, M Schmickl, ...
The Journal of Immunology 199 (7), 2356-2365, 2017
Delivery of immunostimulatory RNA oligonucleotides by gelatin nanoparticles triggers an efficient antitumoral response
C Bourquin, C Wurzenberger, S Heidegger, S Fuchs, D Anz, S Weigel, ...
Journal of immunotherapy 33 (9), 935-944, 2010
TLR and RLR signaling are reprogrammed in opposite directions after detection of viral infection
C Hotz, LC Roetzer, T Huber, A Sailer, A Oberson, M Treinies, ...
The Journal of Immunology 195 (9), 4387-4395, 2015
Targeting intrinsic RIG-I signaling turns melanoma cells into type I interferon-releasing cellular antitumor vaccines
S Bek, F Stritzke, A Wintges, T Nedelko, DFR Böhmer, JC Fischer, T Haas, ...
Oncoimmunology 8 (4), e1570779, 2019
Card9 controls Dectin‐1‐induced T‐cell cytotoxicity and tumor growth in mice
T Haas, S Heidegger, A Wintges, M Bscheider, S Bek, JC Fischer, ...
European Journal of Immunology 47 (5), 872-879, 2017
Innate immune stimulation in cancer therapy
P Düwell, S Heidegger, S Kobold
Hematology/Oncology Clinics 33 (2), 215-231, 2019
Combination therapy with brentuximab vedotin and cisplatin/cytarabine in a patient with primarily refractory anaplastic lymphoma kinase positive anaplastic large cell lymphoma
S Heidegger, AJ Beer, E Geissinger, A Rosenwald, C Peschel, ...
OncoTargets and therapy, 1123-1127, 2014
Type I interferon signaling before hematopoietic stem cell transplantation lowers donor T cell activation via reduced allogenicity of recipient cells
JC Fischer, M Bscheider, S Göttert, E Thiele Orberg, SE Combs, ...
Scientific Reports 9 (1), 14955, 2019
Mycoplasma hyorhinis-Contaminated Cell Lines Activate Primary Innate Immune Cells via a Protease-Sensitive Factor
S Heidegger, A Jarosch, M Schmickl, S Endres, C Bourquin, C Hotz
PloS one 10 (11), e0142523, 2015
Regeneration after radiation-and immune-mediated tissue injury is not enhanced by type III interferon signaling
JC Fischer, CC Lin, S Heidegger, A Wintges, M Schlapschy, M Beudert, ...
International Journal of Radiation Oncology* Biology* Physics 103 (4), 970-976, 2019
Tumor cell‐intrinsic RIG‐I signaling governs synergistic effects of immunogenic cancer therapies and checkpoint inhibitors in mice
H Poeck, A Wintges, S Dahl, F Bassermann, T Haas, S Heidegger
European journal of immunology 51 (6), 1531-1534, 2021
Virus-associated activation of innate immunity induces rapid disruption of Peyer’s patches in mice
S Heidegger, D Anz, N Stephan, B Bohn, T Herbst, WP Fendler, ...
Blood, The Journal of the American Society of Hematology 122 (15), 2591-2599, 2013
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