Covalent trapping of methyllycaconitine at the α4-α4 interface of the α4β2 nicotinic acetylcholine receptor: antagonist binding site and mode of receptor inhibition revealed NL Absalom, G Quek, TM Lewis, T Qudah, I von Arenstorff, JI Ambrus, ... Journal of Biological Chemistry 288 (37), 26521-26532, 2013 | 22 | 2013 |
Revisiting autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) mutations in the nicotinic acetylcholine receptor reveal an increase in efficacy regardless of stochiometry DC Indurthi, T Qudah, VW Liao, PK Ahring, TM Lewis, T Balle, M Chebib, ... Pharmacological Research 139, 215-227, 2019 | 12 | 2019 |
AE Succinimide, an Analogue of Methyllycaconitine, When Bound Generates a Nonconducting Conformation of the α4β2 Nicotinic Acetylcholine Receptor T Qudah, GX Quek, D Indurthi, N Karim, JI Halliday, N Absalom, ... ACS Chemical Neuroscience 11 (3), 344-355, 2020 | 3 | 2020 |
Novel methyllycaconitine analogues selective for the α4β2 over α7 nicotinic acetylcholine receptors R Gallagher, T Qudah, T Balle, M Chebib, MD McLeod Bioorganic & Medicinal Chemistry 51, 116516, 2021 | 2 | 2021 |
Methyllycaconitine Analogues: Pharmacological Evaluation and Binding Site Identification at α4β2 Stoichiometries Nicotinic Acetylcholine Receptors TZM AlQudah | | 2018 |
An additional binding site for methyllycaconitine (MLA) and analogs occurs at the α4–α4 interface of the (α4) 3 (β2) 2 nAChR M Chebib, NL Absalom, G Quek, D Indurthi, TM Lewis, T Qudah, ... Biochemical Pharmacology 8 (86), 1225, 2013 | | 2013 |
Pharmacological Evaluation of Methyllycaconitine and ABT-089 Analogues on Different NAChR [alpha] 4 [beta] 2 Stoichiometries T Alqudah University of Sydney, 2012 | | 2012 |