| The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line Nature genetics 41 (5), 553-562, 2009 | 420 | 2009 |
| Digital twins to personalize medicine B Björnsson, C Borrebaeck, N Elander, T Gasslander, DR Gawel, ... Genome Medicine 12 (1), 1-4, 2019 | 305 | 2019 |
| Modules, networks and systems medicine for understanding disease and aiding diagnosis M Gustafsson, CE Nestor, H Zhang, AL Barabási, S Baranzini, S Brunak, ... Genome medicine 6, 1-11, 2014 | 202 | 2014 |
| Therapeutic efficacy of dimethyl fumarate in relapsing-remitting multiple sclerosis associates with ROS pathway in monocytes KE Carlström, E Ewing, M Granqvist, A Gyllenberg, S Aeinehband, ... Nature communications 10 (1), 3081, 2019 | 132 | 2019 |
| Constructing and analyzing a large-scale gene-to-gene regulatory network Lasso-constrained inference and biological validation M Gustafsson, M Hornquist, A Lombardi IEEE/ACM Transactions on computational biology and bioinformatics 2 (3), 254-261, 2005 | 116 | 2005 |
| DNA Methylation Changes Separate Allergic Patients from Healthy Controls and May Reflect Altered CD4+ T-Cell Population Structure CE Nestor, F Barrenäs, H Wang, A Lentini, H Zhang, S Bruhn, R Jörnsten, ... PLoS genetics 10 (1), e1004059, 2014 | 90 | 2014 |
| Comparison and validation of community structures in complex networks M Gustafsson, M Hörnquist, A Lombardi Physica A: Statistical Mechanics and its Applications 367, 559-576, 2006 | 86 | 2006 |
| A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases DR Gawel, J Serra-Musach, S Lilja, J Aagesen, A Arenas, B Asking, ... Genome medicine 11, 1-25, 2019 | 84 | 2019 |
| ModuleDiscoverer: Identification of regulatory modules in protein-protein interaction networks S Vlaic, T Conrad, C Tokarski-Schnelle, M Gustafsson, U Dahmen, ... Scientific reports 8 (1), 433, 2018 | 78 | 2018 |
| A validated gene regulatory network and GWAS identifies early regulators of T cell–associated diseases M Gustafsson, DR Gawel, L Alfredsson, S Baranzini, J Björkander, ... Science translational medicine 7 (313), 313ra178-313ra178, 2015 | 75 | 2015 |
| 5-Hydroxymethylcytosine remodeling precedes lineage specification during differentiation of human CD4+ T cells CE Nestor, A Lentini, CH Nilsson, DR Gawel, M Gustafsson, L Mattson, ... Cell reports 16 (2), 559-570, 2016 | 71 | 2016 |
| A generally applicable translational strategy identifies S100A4 as a candidate gene in allergy S Bruhn, Y Fang, F Barrenäs, M Gustafsson, H Zhang, A Konstantinell, ... Science translational medicine 6 (218), 218ra4-218ra4, 2014 | 68 | 2014 |
| Dynamic response genes in CD4+ T cells reveal a network of interactive proteins that classifies disease activity in multiple sclerosis S Hellberg, D Eklund, DR Gawel, M Köpsén, H Zhang, CE Nestor, ... Cell reports 16 (11), 2928-2939, 2016 | 51 | 2016 |
| Reverse engineering of gene networks with LASSO and nonlinear basis functions M Gustafsson, M Hörnquist, J Lundström, J Björkegren, J Tegnér Annals of the New York Academy of Sciences 1158 (1), 265-275, 2009 | 50 | 2009 |
| Identification of DNA methylation patterns predisposing for an efficient response to BCG vaccination in healthy BCG-naïve subjects J Das, D Verma, M Gustafsson, M Lerm Epigenetics 14 (6), 589-601, 2019 | 46 | 2019 |
| TET2 as a tumor suppressor and therapeutic target in T-cell acute lymphoblastic leukemia M Bensberg, O Rundquist, A Selimović, C Lagerwall, M Benson, ... Proceedings of the National Academy of Sciences 118 (34), e2110758118, 2021 | 44 | 2021 |
| Deriving disease modules from the compressed transcriptional space embedded in a deep autoencoder SK Dwivedi, A Tjärnberg, J Tegnér, M Gustafsson Nature communications 11 (1), 856, 2020 | 43 | 2020 |
| Gene expression prediction by soft integration and the Elastic Net—Best performance of the DREAM3 gene expression challenge M Gustafsson, M Hörnquist PLoS One 5 (2), e9134, 2010 | 42 | 2010 |
| Integrated genomic and prospective clinical studies show the importance of modular pleiotropy for disease susceptibility, diagnosis and treatment M Gustafsson, M Edström, D Gawel, CE Nestor, H Wang, H Zhang, ... Genome medicine 6, 1-12, 2014 | 36 | 2014 |
| Progesterone Dampens Immune Responses in In Vitro Activated CD4+ T Cells and Affects Genes Associated With Autoimmune Diseases That Improve During … S Hellberg, J Raffetseder, O Rundquist, R Magnusson, G Papapavlou, ... Frontiers in Immunology 12, 672168, 2021 | 32 | 2021 |
mikael bensonMedical Digital Twin Research Group, Karolinska Institute, SwedenVerified email at liu.se
