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Mika Gustafsson
Mika Gustafsson
Professor, Department of Physics, Chemistry and Biology, Linköping University
Verifierad e-postadress på liu.se
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The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line
Nature genetics 41 (5), 553-562, 2009
4182009
Digital twins to personalize medicine
B Björnsson, C Borrebaeck, N Elander, T Gasslander, DR Gawel, ...
Genome Medicine 12 (1), 1-4, 2019
2452019
Modules, networks and systems medicine for understanding disease and aiding diagnosis
M Gustafsson, CE Nestor, H Zhang, AL Barabási, S Baranzini, S Brunak, ...
Genome medicine 6, 1-11, 2014
1972014
Therapeutic efficacy of dimethyl fumarate in relapsing-remitting multiple sclerosis associates with ROS pathway in monocytes
KE Carlström, E Ewing, M Granqvist, A Gyllenberg, S Aeinehband, ...
Nature communications 10 (1), 3081, 2019
1182019
Constructing and analyzing a large-scale gene-to-gene regulatory network Lasso-constrained inference and biological validation
M Gustafsson, M Hornquist, A Lombardi
IEEE/ACM Transactions on computational biology and bioinformatics 2 (3), 254-261, 2005
1122005
Comparison and validation of community structures in complex networks
M Gustafsson, M Hörnquist, A Lombardi
Physica A: Statistical Mechanics and its Applications 367, 559-576, 2006
862006
DNA Methylation Changes Separate Allergic Patients from Healthy Controls and May Reflect Altered CD4+ T-Cell Population Structure
CE Nestor, F Barrenäs, H Wang, A Lentini, H Zhang, S Bruhn, R Jörnsten, ...
PLoS genetics 10 (1), e1004059, 2014
852014
A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases
DR Gawel, J Serra-Musach, S Lilja, J Aagesen, A Arenas, B Asking, ...
Genome medicine 11, 1-25, 2019
792019
A validated gene regulatory network and GWAS identifies early regulators of T cell–associated diseases
M Gustafsson, DR Gawel, L Alfredsson, S Baranzini, J Björkander, ...
Science translational medicine 7 (313), 313ra178-313ra178, 2015
732015
ModuleDiscoverer: Identification of regulatory modules in protein-protein interaction networks
S Vlaic, T Conrad, C Tokarski-Schnelle, M Gustafsson, U Dahmen, ...
Scientific reports 8 (1), 433, 2018
722018
5-Hydroxymethylcytosine remodeling precedes lineage specification during differentiation of human CD4+ T cells
CE Nestor, A Lentini, CH Nilsson, DR Gawel, M Gustafsson, L Mattson, ...
Cell reports 16 (2), 559-570, 2016
702016
A generally applicable translational strategy identifies S100A4 as a candidate gene in allergy
S Bruhn, Y Fang, F Barrenäs, M Gustafsson, H Zhang, A Konstantinell, ...
Science translational medicine 6 (218), 218ra4-218ra4, 2014
632014
Reverse engineering of gene networks with LASSO and nonlinear basis functions
M Gustafsson, M Hörnquist, J Lundström, J Björkegren, J Tegnér
Annals of the New York Academy of Sciences 1158 (1), 265-275, 2009
522009
Dynamic response genes in CD4+ T cells reveal a network of interactive proteins that classifies disease activity in multiple sclerosis
S Hellberg, D Eklund, DR Gawel, M Köpsén, H Zhang, CE Nestor, ...
Cell reports 16 (11), 2928-2939, 2016
512016
Gene expression prediction by soft integration and the Elastic Net—Best performance of the DREAM3 gene expression challenge
M Gustafsson, M Hörnquist
PLoS One 5 (2), e9134, 2010
422010
Deriving disease modules from the compressed transcriptional space embedded in a deep autoencoder
SK Dwivedi, A Tjärnberg, J Tegnér, M Gustafsson
Nature communications 11 (1), 856, 2020
412020
Identification of DNA methylation patterns predisposing for an efficient response to BCG vaccination in healthy BCG-naïve subjects
J Das, D Verma, M Gustafsson, M Lerm
Epigenetics 14 (6), 589-601, 2019
412019
Integrated genomic and prospective clinical studies show the importance of modular pleiotropy for disease susceptibility, diagnosis and treatment
M Gustafsson, M Edström, D Gawel, CE Nestor, H Wang, H Zhang, ...
Genome medicine 6, 1-12, 2014
352014
TET2 as a tumor suppressor and therapeutic target in T-cell acute lymphoblastic leukemia
M Bensberg, O Rundquist, A Selimović, C Lagerwall, M Benson, ...
Proceedings of the National Academy of Sciences 118 (34), e2110758118, 2021
332021
Targeted omics and systems medicine: personalising care
H Zhang, M Gustafsson, C Nestor, KF Chung, M Benson
The Lancet Respiratory Medicine 2 (10), 785-787, 2014
312014
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Artiklar 1–20