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Pete A Williams
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Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice
PA Williams, JM Harder, NE Foxworth, KE Cochran, VM Philip, V Porciatti, ...
Science 355 (6326), 756-760, 2017
4802017
Neuroinflammation in glaucoma: A new opportunity
PA Williams, N Marsh-Armstrong, GR Howell, T Lasker, II on Astrocytes, ...
Experimental eye research 157, 20-27, 2017
2162017
Inhibition of the classical pathway of the complement cascade prevents early dendritic and synaptic degeneration in glaucoma
PA Williams, JR Tribble, KW Pepper, SD Cross, BP Morgan, JE Morgan, ...
Molecular neurodegeneration 11, 1-13, 2016
1682016
A multiethnic genome-wide association study of primary open-angle glaucoma identifies novel risk loci
H Choquet, S Paylakhi, SC Kneeland, KK Thai, TJ Hoffmann, J Yin, ...
Nature Communications 9 (1), 2278, 2018
1522018
Improvement in inner retinal function in glaucoma with nicotinamide (vitamin B3) supplementation: A crossover randomized clinical trial
F Hui, J Tang, PA Williams, MB McGuinness, X Hadoux, RJ Casson, ...
Clinical & Experimental Ophthalmology 48 (7), 903-914, 2020
1302020
Opa1 deficiency in a mouse model of dominant optic atrophy leads to retinal ganglion cell dendropathy
PA Williams, JE Morgan, M Votruba
Brain 133 (10), 2942-2951, 2010
1112010
Retinal ganglion cell dendritic atrophy in DBA/2J glaucoma
PA Williams, GR Howell, JM Barbay, CE Braine, GL Sousa, SWM John, ...
PloS one 8 (8), e72282, 2013
1072013
Retinal ganglion cell dendritic degeneration in a mouse model of Alzheimer's disease
PA Williams, RA Thirgood, H Oliphant, A Frizzati, E Littlewood, M Votruba, ...
Neurobiology of aging 34 (7), 1799-1806, 2013
1072013
Nicotinamide provides neuroprotection in glaucoma by protecting against mitochondrial and metabolic dysfunction
JR Tribble, A Otmani, S Sun, SA Ellis, G Cimaglia, R Vohra, M Jöe, ...
Redox biology 43, 101988, 2021
962021
Early immune responses are independent of RGC dysfunction in glaucoma with complement component C3 being protective
JM Harder, CE Braine, PA Williams, X Zhu, KH MacNicoll, GL Sousa, ...
Proceedings of the National Academy of Sciences 114 (19), E3839-E3848, 2017
922017
Opa1 is essential for retinal ganglion cell synaptic architecture and connectivity
PA Williams, M Piechota, C von Ruhland, E Taylor, JE Morgan, M Votruba
Brain 135 (2), 493-505, 2012
922012
Nicotinamide and WLDS act together to prevent neurodegeneration in glaucoma
PA Williams, JM Harder, NE Foxworth, BH Cardozo, KE Cochran
Frontiers in Neuroscience 11, 232, 2017
822017
Using genetic mouse models to gain insight into glaucoma: Past results and future possibilities
KA Fernandes, JM Harder, PA Williams, RL Rausch, AE Kiernan, KS Nair, ...
Experimental eye research 141, 42-56, 2015
822015
Glaucoma as a metabolic optic neuropathy: making the case for nicotinamide treatment in glaucoma
PA Williams, JM Harder, SWM John
Journal of glaucoma 26 (12), 1161-1168, 2017
772017
Retinal energy metabolism in health and glaucoma
RJ Casson, G Chidlow, JG Crowston, PA Williams, JPM Wood
Progress in Retinal and Eye Research 81, 100881, 2021
672021
Nicotinamide and pyruvate for neuroenhancement in open-angle glaucoma: a phase 2 randomized clinical trial
CG De Moraes, SWM John, PA Williams, DM Blumberg, GA Cioffi, ...
JAMA ophthalmology 140 (1), 11-18, 2022
622022
Nicotinamide treatment robustly protects from inherited mouse glaucoma
PA Williams, JM Harder, BH Cardozo, NE Foxworth, SWM John
Communicative & Integrative Biology 11 (1), e1356956, 2018
622018
Disturbed glucose and pyruvate metabolism in glaucoma with neuroprotection by pyruvate or rapamycin
JM Harder, C Guymer, JPM Wood, E Daskalaki, G Chidlow, C Zhang, ...
Proceedings of the National Academy of Sciences 117 (52), 33619-33627, 2020
612020
A miniature, fiber-coupled, wireless, deep-brain optogenetic stimulator
ST Lee, PA Williams, CE Braine, DT Lin, SWM John, PP Irazoqui
IEEE Transactions on Neural Systems and Rehabilitation Engineering 23 (4 …, 2015
592015
Inhibition of monocyte-like cell extravasation protects from neurodegeneration in DBA/2J glaucoma
PA Williams, CE Braine, K Kizhatil, NE Foxworth, NG Tolman, JM Harder, ...
Molecular neurodegeneration 14 (1), 1-23, 2019
522019
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