Anthony William Paul Fitzpatrick
Anthony William Paul Fitzpatrick
Assistant Professor, Department of Biochemistry & Molecular Biophysics, Columbia University, NYC
Verifierad e-postadress på columbia.edu - Startsida
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Role of intermolecular forces in defining material properties of protein nanofibrils
TP Knowles, AW Fitzpatrick, S Meehan, HR Mott, M Vendruscolo, ...
Science 318 (5858), 1900-1903, 2007
6592007
Cryo-EM structures of tau filaments from Alzheimer’s disease
AWP Fitzpatrick, B Falcon, S He, AG Murzin, G Murshudov, HJ Garringer, ...
Nature 547 (7662), 185-190, 2017
6132017
Atomic structure and hierarchical assembly of a cross-β amyloid fibril
AWP Fitzpatrick, GT Debelouchina, MJ Bayro, DK Clare, MA Caporini, ...
Proceedings of the National Academy of Sciences 110 (14), 5468-5473, 2013
4142013
Metastability of native proteins and the phenomenon of amyloid formation
AJ Baldwin, TPJ Knowles, GG Tartaglia, AW Fitzpatrick, GL Devlin, ...
Journal of the American Chemical Society 133 (36), 14160-14163, 2011
3322011
Inversion of the balance between hydrophobic and hydrogen bonding interactions in protein folding and aggregation
AW Fitzpatrick, TPJ Knowles, CA Waudby, M Vendruscolo, CM Dobson
PLoS Comput Biol 7 (10), e1002169, 2011
742011
Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump
AWP Fitzpatrick, S Llabrés, A Neuberger, JN Blaza, XC Bai, U Okada, ...
Nature Microbiology 2, 17070, 2017
732017
Exceptional rigidity and biomechanics of amyloid revealed by 4D electron microscopy
AWP Fitzpatrick, ST Park, AH Zewail
Proceedings of the National Academy of Sciences 110 (27), 10976-10981, 2013
712013
In-cell NMR characterization of the secondary structure populations of a disordered conformation of α-synuclein within E. coli cells
CA Waudby, C Camilloni, AWP Fitzpatrick, LD Cabrita, CM Dobson, ...
PloS one 8 (8), e72286, 2013
652013
Higher order amyloid fibril structure by MAS NMR and DNP spectroscopy
GT Debelouchina, MJ Bayro, AW Fitzpatrick, V Ladizhansky, MT Colvin, ...
Journal of the American Chemical Society 135 (51), 19237-19247, 2013
642013
Twisting transition between crystalline and fibrillar phases of aggregated peptides
TPJ Knowles, A De Simone, AW Fitzpatrick, A Baldwin, S Meehan, ...
Physical review letters 109 (15), 158101, 2012
482012
Four-dimensional electron microscopy: Ultrafast imaging, diffraction and spectroscopy in materials science and biology
GM Vanacore, AWP Fitzpatrick, AH Zewail
Nano Today 11 (2), 228-249, 2016
472016
Accurate determination of interstrand distances and alignment in amyloid fibrils by magic angle spinning NMR
MA Caporini, VS Bajaj, M Veshtort, A Fitzpatrick, CE MacPhee, ...
The Journal of Physical Chemistry B 114 (42), 13555-13561, 2010
322010
Nanomechanics and intermolecular forces of amyloid revealed by four-dimensional electron microscopy
AWP Fitzpatrick, GM Vanacore, AH Zewail
Proceedings of the National Academy of Sciences 112 (11), 3380-3385, 2015
312015
4D cryo-electron microscopy of proteins
AWP Fitzpatrick, UJ Lorenz, GM Vanacore, AH Zewail
Journal of the American Chemical Society 135 (51), 19123-19126, 2013
272013
Characterizing the first steps of amyloid formation for the ccβ peptide
B Strodel, AW Fitzpatrick, M Vendruscolo, CM Dobson, DJ Wales
The Journal of Physical Chemistry B 112 (32), 9998-10004, 2008
152008
Posttranslational modifications mediate the structural diversity of tauopathy strains
T Arakhamia, CE Lee, Y Carlomagno, DM Duong, SR Kundinger, K Wang, ...
Cell 180 (4), 633-644. e12, 2020
142020
Cryo-EM of amyloid fibrils and cellular aggregates
AWP Fitzpatrick, HR Saibil
Current opinion in structural biology 58, 34-42, 2019
92019
Bottom-up structural proteomics: cryoEM of protein complexes enriched from the cellular milieu
CM Ho, X Li, M Lai, TC Terwilliger, JR Beck, J Wohlschlegel, DE Goldberg, ...
Nature Methods 17 (1), 79-85, 2020
42020
[EC‐03–02]: CRYO‐EM STRUCTURES OF TAU FILAMENTS FROM ALZHEIMER'S DISEASE BRAIN
A Fitzpatrick, B Falcon, S He, A Murzin, G Murshudov, H Garringer, ...
Alzheimer's & Dementia 13 (7S_Part_18), P892-P892, 2017
22017
Bottom-up Structural Proteomics: Cryo-EM of Protein Complexes Enriched from the Cellular Milieu
CM Ho, X Li, M Lai, T Terwilliger, J Beck, JA Wohlschlegel, DE Goldberg, ...
Biophysical Journal 118 (3), 291a, 2020
2020
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