Luigi Bubacco
Luigi Bubacco
Dipartimento di Biologia , UniversitÓ degli Studi di Padova, Italy
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Triggering of inflammasome by aggregated α–synuclein, an inflammatory response in synucleinopathies
G Codolo, N Plotegher, T Pozzobon, M Brucale, I Tessari, L Bubacco, ...
PloS one 8 (1), e55375, 2013
Kinetic and structural analysis of the early oxidation products of dopamine: analysis of the interactions with α-synuclein
M Bisaglia, S Mammi, L Bubacco
Journal of Biological Chemistry 282 (21), 15597-15605, 2007
Impaired dopamine metabolism in Parkinson’s disease pathogenesis
A Masato, N Plotegher, D Boassa, L Bubacco
Molecular neurodegeneration 14 (1), 35, 2019
Conformational equilibria in monomeric α-synuclein at the single-molecule level
M Sandal, F Valle, I Tessari, S Mammi, E Bergantino, F Musiani, ...
PLoS biology 6 (1), e6, 2008
LRRK2 and neuroinflammation: partners in crime in Parkinson’s disease?
I Russo, L Bubacco, E Greggio
Journal of neuroinflammation 11, 1-9, 2014
Structural insights on physiological functions and pathological effects of▒‐synuclein
M Bisaglia, S Mammi, L Bubacco
The FASEB Journal 23 (2), 329-340, 2009
GTPase activity regulates kinase activity and cellular phenotypes of Parkinson's disease-associated LRRK2
A Biosa, A Trancikova, L Civiero, L Glauser, L Bubacco, E Greggio, ...
Human molecular genetics 22 (6), 1140-1156, 2013
COVID-19 and possible links with Parkinson’s disease and parkinsonism: from bench to bedside
D Sulzer, A Antonini, V Leta, A Nordvig, RJ Smeyne, JE Goldman, ...
npj Parkinson's Disease 6 (1), 18, 2020
A topological model of the interaction between α-synuclein and sodium dodecyl sulfate micelles
M Bisaglia, I Tessari, L Pinato, M Bellanda, S Giraudo, M Fasano, ...
Biochemistry 44 (1), 329-339, 2005
The reaction of α-synuclein with tyrosinase: Possible implications for Parkinson disease
I Tessari, M Bisaglia, F Valle, B Samorý, E Bergantino, S Mammi, ...
Journal of biological chemistry 283 (24), 16808-16817, 2008
Tyrosinase exacerbates dopamine toxicity but is not genetically associated with Parkinson's disease
E Greggio, E Bergantino, D Carter, R Ahmad, GE Costin, VJ Hearing, ...
Journal of neurochemistry 93 (1), 246-256, 2005
Copper ions and Parkinson’s disease: why is homeostasis so relevant?
M Bisaglia, L Bubacco
Biomolecules 10 (2), 195, 2020
DOPAL derived alpha-synuclein oligomers impair synaptic vesicles physiological function
N Plotegher, G Berti, E Ferrari, I Tessari, M Zanetti, L Lunelli, E Greggio, ...
Scientific reports 7 (1), 40699, 2017
Leucine-rich repeat kinase 2 positively regulates inflammation and down-regulates NF-κB p50 signaling in cultured microglia cells
I Russo, G Berti, N Plotegher, G Bernardo, R Filograna, L Bubacco, ...
Journal of neuroinflammation 12, 1-13, 2015
Biochemical characterization of highly purified leucine-rich repeat kinases 1 and 2 demonstrates formation of homodimers
L Civiero, R Vancraenenbroeck, E Belluzzi, A Beilina, E Lobbestael, ...
Public Library of Science 7 (8), e43472, 2012
Exosomes-associated neurodegeneration and progression of Parkinson’s disease
I Russo, L Bubacco, E Greggio
American journal of neurodegenerative disease 1 (3), 217, 2012
Alpha-synuclein pore forming activity upon membrane association
L Tosatto, AO Andrighetti, N Plotegher, V Antonini, I Tessari, L Ricci, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1818 (11), 2876-2883, 2012
Structural and morphological characterization of aggregated species of α-synuclein induced by docosahexaenoic acid
G De Franceschi, E Frare, M Pivato, A Relini, A Penco, E Greggio, ...
Journal of Biological Chemistry 286 (25), 22262-22274, 2011
Dopamine quinones interact with α-synuclein to form unstructured adducts
M Bisaglia, L Tosatto, F Munari, I Tessari, PP de Laureto, S Mammi, ...
Biochemical and Biophysical Research Communications 394 (2), 424-428, 2010
LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complex
MD Cirnaru, A Marte, E Belluzzi, I Russo, M Gabrielli, F Longo, L Arcuri, ...
Frontiers in molecular neuroscience 7, 49, 2014
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