David Adams
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PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization
MD Houslay, DR Adams
Biochemical Journal 370 (1), 1-18, 2003
RACK1, A multifaceted scaffolding protein: Structure and function
DR Adams, D Ron, PA Kiely
Cell Communication and Signaling 9 (1), 22, 2011
The development of a marine natural product-based antifouling paint
JG Burgess, KG Boyd, E Armstrong, Z Jiang, L Yan, M Berggren, U May, ...
Biofouling 19 (S1), 197-205, 2003
Sphingosine 1-phosphate and sphingosine kinases in health and disease: recent advances
S Pyne, DR Adams, NJ Pyne
Progress in Lipid Research 62, 93-106, 2016
Scanning peptide array analyses identify overlapping binding sites for the signalling scaffold proteins, β-arrestin and RACK1, in cAMP-specific phosphodiesterase PDE4D5
GB Bolger, GS Baillie, X Li, MJ Lynch, P Herzyk, A Mohamed, ...
Biochemical Journal 398 (1), 23-36, 2006
Novel anti-infective compounds from marine bacteria
H Rahman, B Austin, WJ Mitchell, PC Morris, DJ Jamieson, DR Adams, ...
Marine drugs 8 (3), 498-518, 2010
Biofilm-specific cross-species induction of antimicrobial compounds in bacilli
L Yan, KG Boyd, DR Adams, JG Burgess
Applied and Environmental Microbiology 69 (7), 3719-3727, 2003
Antibacterial and repellent activities of marine bacteria associated with algal surfaces
KG Boyd, DR Adams, JG Burgess
Biofouling 14 (3), 227-236, 1999
Phosphorylation of RACK1 on tyrosine 52 by c-Abl is required for insulin-like growth factor I-mediated regulation of focal adhesion kinase
PA Kiely, GS Baillie, R Barrett, DA Buckley, DR Adams, MD Houslay, ...
Journal of Biological Chemistry 284 (30), 20263-20274, 2009
Disruption of the cyclic AMP phosphodiesterase-4 (PDE4)–HSP20 complex attenuates the β-agonist induced hypertrophic response in cardiac myocytes
YY Sin, HV Edwards, X Li, JP Day, F Christian, AJ Dunlop, DR Adams, ...
Journal of Molecular and Cellular Cardiology 50 (5), 872-883, 2011
Mapping binding sites for the PDE4D5 cAMP-specific phosphodiesterase to the N-and C-domains of β-arrestin using spot-immobilized peptide arrays
GS Baillie, DR Adams, N Bhari, TM Houslay, S Vadrevu, D Meng, X Li, ...
Biochemical Journal 404 (1), 71-80, 2007
Sphingosine 1-phosphate and cancer
NJ Pyne, A El Buri, DR Adams, S Pyne
Advances in Biological Regulation 68, 97-106, 2018
Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs
BD Hudson, E Christiansen, IG Tikhonova, M Grundmann, E Kostenis, ...
The FASEB Journal 26 (12), 4951-4965, 2012
Extracellular loop 2 of the free fatty acid receptor 2 mediates allosterism of a phenylacetamide ago-allosteric modulator
NJ Smith, RJ Ward, LA Stoddart, BD Hudson, E Kostenis, T Ulven, ...
Molecular Pharmacology 80 (1), 163-173, 2011
Sphingosine kinases: emerging structure–function insights
DR Adams, S Pyne, NJ Pyne
Trends in Biochemical Sciences 41 (5), 395-409, 2016
MEK1 binds directly to βarrestin1, influencing both its phosphorylation by ERK and the timing of its isoprenaline-stimulated internalization
D Meng, MJ Lynch, E Huston, M Beyermann, J Eichhorst, DR Adams, ...
Journal of Biological Chemistry 284 (17), 11425-11435, 2009
Two Diketopiperazines and One Halogenated Phenol from Cultures of the Marine Bacterium, Pseudoalteromonas luteoviolacea
Z Jiang, KG Boyd, A Mearns-Spragg, DR Adams, PC Wright, JG Burgess
Natural Product Letters 14 (6), 435-440, 2000
1H NMR structural and functional characterisation of a cAMP-specific phosphodiesterase-4D5 (PDE4D5) N-terminal region peptide that disrupts PDE4D5 interaction with the …
KJ Smith, GS Baillie, EI Hyde, X Li, TM Houslay, A McCahill, AJ Dunlop, ...
Cellular Signalling 19 (12), 2612-2624, 2007
JM47, a cyclic tetrapeptide HC-toxin analogue from a marine Fusarium species
Z Jiang, MO Barret, KG Boyd, DR Adams, ASF Boyd, JG Burgess
Phytochemistry 60 (1), 33-38, 2002
Small-molecule allosteric activators of PDE4 long form cyclic AMP phosphodiesterases
F Omar, JE Findlay, G Carfray, RW Allcock, Z Jiang, C Moore, AL Muir, ...
Proceedings of the National Academy of Sciences 116 (27), 13320-13329, 2019
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