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Winfried Barchet
Winfried Barchet
OMass Therapeutics, VP Immunology
Verifierad e-postadress på omass.com
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Human T regulatory cells can use the perforin pathway to cause autologous target cell death
WJ Grossman, JW Verbsky, W Barchet, M Colonna, JP Atkinson, TJ Ley
Immunity 21 (4), 589-601, 2004
14712004
Essential role of mda-5 in type I IFN responses to polyriboinosinic: polyribocytidylic acid and encephalomyocarditis picornavirus
L Gitlin, W Barchet, S Gilfillan, M Cella, B Beutler, RA Flavell, ...
Proceedings of the National Academy of Sciences 103 (22), 8459-8464, 2006
14092006
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3
TD Kanneganti, N Özören, M Body-Malapel, A Amer, JH Park, L Franchi, ...
Nature 440 (7081), 233-236, 2006
13172006
Cyclic [G (2′, 5′) pA (3′, 5′) p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase
P Gao, M Ascano, Y Wu, W Barchet, BL Gaffney, T Zillinger, AA Serganov, ...
Cell 153 (5), 1094-1107, 2013
9532013
TLR9-dependent recognition of MCMV by IPC and DC generates coordinated cytokine responses that activate antiviral NK cell function
A Krug, AR French, W Barchet, JAA Fischer, A Dzionek, JT Pingel, ...
Immunity 21 (1), 107-119, 2004
9452004
Recognition of 5′ triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus
M Schlee, A Roth, V Hornung, CA Hagmann, V Wimmenauer, W Barchet, ...
Immunity 31 (1), 25-34, 2009
9382009
Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9
A Krug, GD Luker, W Barchet, DA Leib, S Akira, M Colonna
Blood 103 (4), 1433-1437, 2004
9312004
Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5
R Züst, L Cervantes-Barragan, M Habjan, R Maier, BW Neuman, ...
Nature immunology 12 (2), 137-143, 2011
8272011
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1β production
H Poeck, M Bscheider, O Gross, K Finger, S Roth, M Rebsamen, ...
Nature immunology 11 (1), 63-69, 2010
6522010
Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5′-diphosphates
D Goubau, M Schlee, S Deddouche, AJ Pruijssers, T Zillinger, M Goldeck, ...
Nature 514 (7522), 372-375, 2014
6042014
Structure-function analysis of STING activation by c [G (2′, 5′) pA (3′, 5′) p] and targeting by antiviral DMXAA
P Gao, M Ascano, T Zillinger, W Wang, P Dai, AA Serganov, BL Gaffney, ...
Cell 154 (4), 748-762, 2013
5432013
Oxidative damage of DNA confers resistance to cytosolic nuclease TREX1 degradation and potentiates STING-dependent immune sensing
N Gehrke, C Mertens, T Zillinger, J Wenzel, T Bald, S Zahn, T Tüting, ...
Immunity 39 (3), 482-495, 2013
4102013
Virus-induced interferon α production by a dendritic cell subset in the absence of feedback signaling in vivo
W Barchet, M Cella, B Odermatt, C Asselin-Paturel, M Colonna, U Kalinke
The Journal of experimental medicine 195 (4), 507-516, 2002
3192002
Targeted disruption of LIGHT causes defects in costimulatory T cell activation and reveals cooperation with lymphotoxin β in mesenteric lymph node genesis
S Scheu, J Alferink, T Pötzel, W Barchet, U Kalinke, K Pfeffer
The Journal of experimental medicine 195 (12), 1613-1624, 2002
3172002
Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection
P Liehl, V Zuzarte-Luís, J Chan, T Zillinger, F Baptista, D Carapau, ...
Nature medicine 20 (1), 47-53, 2014
3132014
CD8+ T cells orchestrate pDC-XCR1+ dendritic cell spatial and functional cooperativity to optimize priming
A Brewitz, S Eickhoff, S Dähling, T Quast, S Bedoui, RA Kroczek, C Kurts, ...
Immunity 46 (2), 205-219, 2017
3022017
PKR and RNase L contribute to protection against lethal West Nile Virus infection by controlling early viral spread in the periphery and replication in neurons
MA Samuel, K Whitby, BC Keller, A Marri, W Barchet, BRG Williams, ...
Journal of virology 80 (14), 7009-7019, 2006
2992006
A conserved histidine in the RNA sensor RIG-I controls immune tolerance to N1-2′ O-methylated self RNA
C Schuberth-Wagner, J Ludwig, AK Bruder, AM Herzner, T Zillinger, ...
Immunity 43 (1), 41-51, 2015
2792015
Plasmacytoid dendritic cells—virus experts of innate immunity
W Barchet, M Cella, M Colonna
Seminars in immunology 17 (4), 253-261, 2005
2692005
Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA
AM Herzner, CA Hagmann, M Goldeck, S Wolter, K Kübler, S Wittmann, ...
Nature immunology 16 (10), 1025-1033, 2015
2432015
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