Följ
S.Tiong Ong
S.Tiong Ong
Duke-NUS Medical School
Verifierad e-postadress på duke-nus.edu.sg
Titel
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A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer
KP Ng, AM Hillmer, CTH Chuah, WC Juan, TK Ko, ASM Teo, ...
Nature medicine 18 (4), 521-528, 2012
6622012
Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor
MR Janes, JJ Limon, L So, J Chen, RJ Lim, MA Chavez, C Vu, MB Lilly, ...
Nature medicine 16 (2), 205-213, 2010
4772010
Chemotherapy in malignant pleural mesothelioma. A review.
ST Ong, NJ Vogelzang
Journal of Clinical Oncology 14 (3), 1007-1017, 1996
3101996
FHIT and FRA3B 3p14.2 Allele Loss Are Common in Lung Cancer and Preneoplastic Bronchial Lesions and Are Associated with Cancer-related FHIT cDNA …
KM Fong, EJ Biesterveld, A Virmani, I Wistuba, Y Sekido, SA Bader, ...
Cancer research 57 (11), 2256-2267, 1997
2681997
Bcr-Abl kinase modulates the translation regulators ribosomal protein S6 and 4E-BP1 in chronic myelogenous leukemia cells via the mammalian target of rapamycin
C Ly, AF Arechiga, JV Melo, CM Walsh, ST Ong
Cancer research 63 (18), 5716-5722, 2003
2262003
Targeting of the MNK–eIF4E axis in blast crisis chronic myeloid leukemia inhibits leukemia stem cell function
S Lim, TY Saw, M Zhang, MR Janes, K Nacro, J Hill, AQ Lim, CT Chang, ...
Proceedings of the National Academy of Sciences 110 (25), E2298-E2307, 2013
1562013
Laying the foundation for genomically-based risk assessment in chronic myeloid leukemia
S Branford, DDH Kim, JF Apperley, CA Eide, S Mustjoki, ST Ong, ...
Leukemia 33 (8), 1835-1850, 2019
1292019
Physiologic hypoxia promotes maintenance of CML stem cells despite effective BCR-ABL1 inhibition
KP Ng, A Manjeri, KL Lee, W Huang, SY Tan, CTH Chuah, L Poellinger, ...
Blood, The Journal of the American Society of Hematology 123 (21), 3316-3326, 2014
1002014
Lymphadenopathy, splenomegaly, and altered immunoglobulin production in BCL3 transgenic mice
ST Ong, ML Hackbarth, LC Degenstein, DA Baunoch, J Anastasi, ...
Oncogene 16 (18), 2333-2343, 1998
971998
Histone Deacetylase 3 Inhibition Overcomes BIM Deletion Polymorphism–Mediated Osimertinib Resistance in EGFR-Mutant Lung Cancer
A Tanimoto, S Takeuchi, S Arai, K Fukuda, T Yamada, X Roca, ST Ong, ...
Clinical Cancer Research 23 (12), 3139-3149, 2017
882017
Inhibition of polysome assembly enhances imatinib activity against chronic myelogenous leukemia and overcomes imatinib resistance
M Zhang, W Fu, S Prabhu, JC Moore, J Ko, JW Kim, BJ Druker, V Trapp, ...
Molecular and cellular biology, 2008
792008
Chromosomal abnormalities and molecular genetics of non-Hodgkin's lymphoma.
ST Ong, MM Le Beau
Seminars in oncology 25 (4), 447-460, 1998
751998
The BCL2 inhibitor ABT-199 significantly enhances imatinib-induced cell death in chronic myeloid leukemia progenitors
TK Ko, CTH Chuah, JWJ Huang, KP Ng, ST Ong
Oncotarget 5 (19), 9033, 2014
702014
A novel mechanism for Bcr-Abl action: Bcr-Abl-mediated induction of the eIF4F translation initiation complex and mRNA translation
S Prabhu, D Saadat, M Zhang, L Halbur, JP Fruehauf, ST Ong
Oncogene 26 (8), 1188-1200, 2007
682007
Direct cloning of DNA sequences from the common fragile site region at chromosome band 3p14. 2
FV Rassool, MM Le Beau, ML Shen, ME Neilly, R Espinosa III, ST Ong, ...
Genomics 35 (1), 109-117, 1996
631996
An integrative model of pathway convergence in genetically heterogeneous blast crisis chronic myeloid leukemia
TK Ko, A Javed, KL Lee, TN Pathiraja, X Liu, S Malik, SX Soh, XT Heng, ...
Blood, The Journal of the American Society of Hematology 135 (26), 2337-2353, 2020
542020
A Fas-associated death domain protein/caspase-8-signaling axis promotes S-phase entry and maintains S6 kinase activity in T cells responding to IL-2
AF Arechiga, BD Bell, S Leverrier, BM Weist, M Porter, Z Wu, Y Kanno, ...
The Journal of Immunology 179 (8), 5291-5300, 2007
372007
Precise localization of the FHIT gene to the common fragile site at 3p14. 2 (FRA3B) and characterization of homozygous deletions within FRA3B that affect FHIT transcription in …
ST Ong, KM Fong, SA Bader, JD Minna, MM Le Beau, TW McKeithan, ...
Genes, Chromosomes and Cancer 20 (1), 16-23, 1997
371997
Identification of cis-acting elements and splicing factors involved in the regulation of BIM Pre-mRNA splicing
WC Juan, X Roca, ST Ong
PloS one 9 (4), e95210, 2014
362014
Phase I study of vorinostat with gefitinib in BIM deletion polymorphism/epidermal growth factor receptor mutation double‐positive lung cancer
S Takeuchi, T Hase, S Shimizu, M Ando, A Hata, H Murakami, ...
Cancer science 111 (2), 561-570, 2020
352020
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