| 3′ non-coding region sequences in eukaryotic messenger RNA NJ Proudfoot, GG Brownlee Nature 263 (5574), 211-214, 1976 | 3335 | 1976 |
| The structure and evolution of the human β-globin gene family A Efstratiadis, JW Posakony, T Maniatis, RM Lawn, C O'Connell, RA Spritz, ... Cell 21 (3), 653-668, 1980 | 1672 | 1980 |
| Human senataxin resolves RNA/DNA hybrids formed at transcriptional pause sites to promote Xrn2-dependent termination K Skourti-Stathaki, NJ Proudfoot, N Gromak Molecular cell 42 (6), 794-805, 2011 | 888 | 2011 |
| Mapping the human genetic architecture of COVID-19 Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ... Nature 600 (7889), 472-477, 2021 | 810 | 2021 |
| A double-edged sword: R loops as threats to genome integrity and powerful regulators of gene expression K Skourti-Stathaki, NJ Proudfoot Genes & development 28 (13), 1384-1396, 2014 | 600 | 2014 |
| Mammalian NET-seq reveals genome-wide nascent transcription coupled to RNA processing T Nojima, T Gomes, ARF Grosso, H Kimura, MJ Dye, S Dhir, ... Cell 161 (3), 526-540, 2015 | 579 | 2015 |
| Mitochondrial double-stranded RNA triggers antiviral signalling in humans A Dhir, S Dhir, LS Borowski, L Jimenez, M Teitell, A Rötig, YJ Crow, ... Nature 560 (7717), 238-242, 2018 | 519 | 2018 |
| BRCA1 recruitment to transcriptional pause sites is required for R-loop-driven DNA damage repair E Hatchi, K Skourti-Stathaki, S Ventz, L Pinello, A Yen, ... Molecular cell 57 (4), 636-647, 2015 | 493 | 2015 |
| Transcriptional interference and termination between duplicated α-globin gene constructs suggests a novel mechanism for gene regulation NJ Proudfoot Nature 322 (6079), 562-565, 1986 | 473 | 1986 |
| Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing CJ Webby, A Wolf, N Gromak, M Dreger, H Kramer, B Kessler, ML Nielsen, ... Science 325 (5936), 90-93, 2009 | 470 | 2009 |
| α-Thalassaemia caused by a polyadenylation signal mutation DR Higgs, SEY Goodbourn, J Lamb, JB Clegg, DJ Weatherall, ... Nature 306 (5941), 398-400, 1983 | 453 | 1983 |
| A single-base change at a splice site in a β0-thalassemic gene causes abnormal RNA splicing R Treisman, NJ Proudfoot, M Shander, T Maniatis Cell 29 (3), 903-911, 1982 | 427 | 1982 |
| R-loops induce repressive chromatin marks over mammalian gene terminators K Skourti-Stathaki, K Kamieniarz-Gdula, NJ Proudfoot Nature 516 (7531), 436-439, 2014 | 423 | 2014 |
| R-loop stabilization represses antisense transcription at the Arabidopsis FLC locus Q Sun, T Csorba, K Skourti-Stathaki, NJ Proudfoot, C Dean Science 340 (6132), 619-621, 2013 | 393 | 2013 |
| The structure of the human zeta-globin gene and a closely linked, nearly identical pseudogene NJ Proudfoot, A Gil, T Maniatis Cell 31 (3), 553-563, 1982 | 380 | 1982 |
| Position-dependent sequence elements downstream of AAUAAA are required for efficient rabbit β-globin mRNA 3′ end formation A Gil, NJ Proudfoot Cell 49 (3), 399-406, 1987 | 322 | 1987 |
| The structure of a human α-globin pseudogene and its relationship to α-globin gene duplication NJ Proudfoot, T Maniatis Cell 21 (2), 537-544, 1980 | 319 | 1980 |
| Structure and in vitro transcription of human globin genes NJ Proudfoot, MHM Shander, JL Manley, ML Gefter, T Maniatis Science 209 (4463), 1329-1336, 1980 | 293 | 1980 |
| A sequence downstream of AAUAAA is required for rabbit β-globin mRNA 3′-end formation A Gil, NJ Proudfoot Nature 312 (5993), 473-474, 1984 | 290 | 1984 |
| Sequence at the 3′ end of globin mRNA shows homology with immunoglobulin light chain mRNA NJ Proudfoot, GG Brownlee Nature 252 (5482), 359-362, 1974 | 274 | 1974 |
