Stefan Feske
Stefan Feske
Professor & Vice Chair (Pathology), Jeffrey Bergstein Professor (Medicine), New York University
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A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function
S Feske, Y Gwack, M Prakriya, S Srikanth, SH Puppel, B Tanasa, ...
Nature 441 (7090), 179-185, 2006
Orai1 is an essential pore subunit of the CRAC channel
M Prakriya, S Feske, Y Gwack, S Srikanth, A Rao, PG Hogan
Nature 443 (7108), 230-233, 2006
Calcium signalling in lymphocyte activation and disease
S Feske
Nature Reviews Immunology 7 (9), 690-702, 2007
Gene regulation mediated by calcium signals in T lymphocytes
S Feske, J Giltnane, R Dolmetsch, LM Staudt, A Rao
Nature immunology 2 (4), 316-324, 2001
Phosphoenolpyruvate is a metabolic checkpoint of anti-tumor T cell responses
PC Ho, JD Bihuniak, AN Macintyre, M Staron, X Liu, R Amezquita, ...
Cell 162 (6), 1217-1228, 2015
Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins
V Heissmeyer, F Macián, SH Im, R Varma, S Feske, K Venuprasad, H Gu, ...
Nature immunology 5 (3), 255-265, 2004
Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance
M Oh-Hora, M Yamashita, PG Hogan, S Sharma, E Lamperti, W Chung, ...
Nature immunology 9 (4), 432-443, 2008
STIM1 mutation associated with a syndrome of immunodeficiency and autoimmunity
C Picard, CA McCarl, A Papolos, S Khalil, K Lüthy, C Hivroz, F LeDeist, ...
New England Journal of Medicine 360 (19), 1971-1980, 2009
Biochemical and functional characterization of Orai proteins
Y Gwack, S Srikanth, S Feske, F Cruz-Guilloty, M Oh-hora, DS Neems, ...
Journal of Biological Chemistry 282 (22), 16232-16243, 2007
A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT
Y Gwack, S Sharma, J Nardone, B Tanasa, A Iuga, S Srikanth, H Okamura, ...
Nature 441 (7093), 646-650, 2006
Ion channels and transporters in lymphocyte function and immunity
S Feske, EY Skolnik, M Prakriya
Nature Reviews Immunology 12 (7), 532-547, 2012
Signalling to transcription: store-operated Ca2+ entry and NFAT activation in lymphocytes
Y Gwack, S Feske, S Srikanth, PG Hogan, A Rao
Cell calcium 42 (2), 145-156, 2007
Perforin triggers a plasma membrane-repair response that facilitates CTL induction of apoptosis
D Keefe, L Shi, S Feske, R Massol, F Navarro, T Kirchhausen, ...
Immunity 23 (3), 249-262, 2005
ORAI1 and STIM1 deficiency in human and mice: roles of store‐operated Ca2+ entry in the immune system and beyond
S Feske
Immunological reviews 231 (1), 189-209, 2009
Hair loss and defective T-and B-cell function in mice lacking ORAI1
Y Gwack, S Srikanth, M Oh-Hora, PG Hogan, ED Lamperti, M Yamashita, ...
Molecular and cellular biology 28 (17), 5209-5222, 2008
Whole-exome sequencing-based discovery of STIM1 deficiency in a child with fatal classic Kaposi sarcomaSTIM1 deficiency discovered by whole-exome sequencing
M Byun, A Abhyankar, V Lelarge, S Plancoulaine, A Palanduz, L Telhan, ...
The Journal of experimental medicine 207 (11), 2307-2312, 2010
Ion channels in innate and adaptive immunity
S Feske, H Wulff, EY Skolnik
Annual review of immunology 33, 291-353, 2015
ORAI1 deficiency and lack of store-operated Ca2+ entry cause immunodeficiency, myopathy, and ectodermal dysplasia
CA McCarl, C Picard, S Khalil, T Kawasaki, J Röther, A Papolos, J Kutok, ...
Journal of Allergy and Clinical Immunology 124 (6), 1311-1318. e7, 2009
A severe defect in CRAC Ca2+ channel activation and altered K+ channel gating in T cells from immunodeficient patients
S Feske, M Prakriya, A Rao, RS Lewis
The Journal of experimental medicine 202 (5), 651-662, 2005
A minimal regulatory domain in the C terminus of STIM1 binds to and activates ORAI1 CRAC channels
T Kawasaki, I Lange, S Feske
Biochemical and biophysical research communications 385 (1), 49-54, 2009
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Artiklar 1–20