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Kit Curtius
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An evolutionary perspective on field cancerization
K Curtius, NA Wright, TA Graham
Nature Reviews Cancer 18 (1), 19-32, 2018
4042018
The 2019 mathematical oncology roadmap
RC Rockne, A Hawkins-Daarud, KR Swanson, JP Sluka, JA Glazier, ...
Physical biology 16 (4), 041005, 2019
1712019
Evolutionary history of human colitis-associated colorectal cancer
AM Baker, W Cross, K Curtius, I Al Bakir, CHR Choi, HL Davis, D Temko, ...
Gut 68 (6), 985-995, 2019
1372019
Impact of tumor progression on cancer incidence curves
EG Luebeck, K Curtius, J Jeon, WD Hazelton
Cancer research 73 (3), 1086-1096, 2013
952013
Exploring the recent trend in esophageal adenocarcinoma incidence and mortality using comparative simulation modeling
CY Kong, S Kroep, K Curtius, WD Hazelton, J Jeon, R Meza, CR Heberle, ...
Cancer epidemiology, biomarkers & prevention 23 (6), 997-1006, 2014
712014
The role of gastroesophageal reflux and other factors during progression to esophageal adenocarcinoma
WD Hazelton, K Curtius, JM Inadomi, TL Vaughan, R Meza, ...
Cancer Epidemiology, Biomarkers & Prevention 24 (7), 1012-1023, 2015
492015
Computational modelling suggests that Barrett’s oesophagus may be the precursor of all oesophageal adenocarcinomas
K Curtius, JH Rubenstein, A Chak, JM Inadomi
Gut 70 (8), 1435-1440, 2021
432021
A molecular clock infers heterogeneous tissue age among patients with Barrett’s esophagus
K Curtius, CJ Wong, WD Hazelton, AM Kaz, A Chak, JE Willis, WM Grady, ...
PLoS computational biology 12 (5), e1004919, 2016
392016
The mutational signatures of formalin fixation on the human genome
Q Guo, E Lakatos, IA Bakir, K Curtius, TA Graham, V Mustonen
Nature Communications 13 (1), 4487, 2022
382022
Specific mechanisms of chromosomal instability indicate therapeutic sensitivities in high-grade serous ovarian carcinoma
N Tamura, N Shaikh, D Muliaditan, TN Soliman, JR McGuinness, ...
Cancer research 80 (22), 4946-4959, 2020
372020
From colitis to cancer: an evolutionary trajectory that merges maths and biology
I Al Bakir, K Curtius, TA Graham
Frontiers in immunology 9, 414855, 2018
322018
Evolution of premalignant disease
K Curtius, NA Wright, TA Graham
Cold Spring Harbor Perspectives in Medicine 7 (12), a026542, 2017
322017
Implications of epigenetic drift in colorectal neoplasia
GE Luebeck, WD Hazelton, K Curtius, SK Maden, M Yu, KT Carter, ...
Cancer research 79 (3), 495-504, 2019
312019
A multiscale model evaluates screening for neoplasia in Barrett’s esophagus
K Curtius, WD Hazelton, J Jeon, EG Luebeck
PLoS computational biology 11 (5), e1004272, 2015
282015
Identification of a key role of widespread epigenetic drift in Barrett’s esophagus and esophageal adenocarcinoma
EG Luebeck, K Curtius, WD Hazelton, S Maden, M Yu, PN Thota, DT Patil, ...
Clinical epigenetics 9, 1-10, 2017
252017
Radiofrequency ablation of Barrett's esophagus reduces esophageal adenocarcinoma incidence and mortality in a comparative modeling analysis
S Kroep, CR Heberle, K Curtius, CY Kong, I Lansdorp-Vogelaar, A Ali, ...
Clinical Gastroenterology and Hepatology 15 (9), 1471-1474, 2017
232017
Multicentre derivation and validation of a colitis-associated colorectal cancer risk prediction web tool
K Curtius, M Kabir, I Al Bakir, CHR Choi, JL Hartono, M Johnson, JE East, ...
Gut 71 (4), 705-715, 2022
182022
Cancer's second genome: microbial cancer diagnostics and redefining clonal evolution as a multispecies process: humans and their tumors are not aseptic, and the multispecies …
GD Sepich‐Poore, C Guccione, L Laplane, T Pradeu, K Curtius, R Knight
BioEssays 44 (5), 2100252, 2022
142022
Lynch Syndrome—a mechanistic and clinical management update
K Curtius, S Gupta, CR Boland
Alimentary pharmacology & therapeutics 55 (8), 960-977, 2022
102022
Optimal timing for cancer screening and adaptive surveillance using mathematical modeling
K Curtius, A Dewanji, WD Hazelton, JH Rubenstein, GE Luebeck
Cancer research 81 (4), 1123-1134, 2021
72021
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Articles 1–20