| Monomeric and polymeric gram-negative peptidoglycan but not purified LPS stimulate the Drosophila IMD pathway T Kaneko, WE Goldman, P Mellroth, H Steiner, K Fukase, S Kusumoto, ... Immunity 20 (5), 637-649, 2004 | 505 | 2004 |
| A scavenger function for a DrosophilaPeptidoglycan recognition protein P Mellroth, J Karlsson, H Steiner Journal of Biological Chemistry 278 (9), 7059-7064, 2003 | 396 | 2003 |
| Functional diversity of the Drosophila PGRP-LC gene cluster in the response to lipopolysaccharide and peptidoglycan T Werner, K Borge-Renberg, P Mellroth, H Steiner, D Hultmark Journal of Biological Chemistry 278 (29), 26319-26322, 2003 | 244 | 2003 |
| LytA, major autolysin of Streptococcus pneumoniae, requires access to nascent peptidoglycan P Mellroth, R Daniels, A Eberhardt, D Rönnlund, H Blom, J Widengren, ... Journal of Biological Chemistry 287 (14), 11018-11029, 2012 | 184 | 2012 |
| PGRP-SB1: an N-acetylmuramoyl L-alanine amidase with antibacterial activity P Mellroth, H Steiner Biochemical and biophysical research communications 350 (4), 994-999, 2006 | 167 | 2006 |
| Detection of human disease conditions by single-cell morpho-rheological phenotyping of blood N Toepfner, C Herold, O Otto, P Rosendahl, A Jacobi, M Kräter, ... elife 7, e29213, 2018 | 140 | 2018 |
| Ligand-induced dimerization of Drosophila peptidoglycan recognition proteins in vitro P Mellroth, J Karlsson, J Håkansson, N Schultz, WE Goldman, H Steiner Proceedings of the National Academy of Sciences 102 (18), 6455-6460, 2005 | 130 | 2005 |
| Disulfide Bond Formation and Cysteine Exclusion in Gram-positive Bacteria*♦ R Daniels, P Mellroth, A Bernsel, F Neiers, S Normark, G von Heijne, ... Journal of Biological Chemistry 285 (5), 3300-3309, 2010 | 108 | 2010 |
| pIgR and PECAM-1 bind to pneumococcal adhesins RrgA and PspC mediating bacterial brain invasion F Iovino, JY Engelen-Lee, M Brouwer, D van de Beek, A van der Ende, ... Journal of Experimental Medicine 214 (6), 1619-1630, 2017 | 100 | 2017 |
| Human monocytes promote Th1 and Th17 responses to Streptococcus pneumoniae M Olliver, J Hiew, P Mellroth, B Henriques-Normark, P Bergman Infection and immunity 79 (10), 4210-4217, 2011 | 88 | 2011 |
| Structural and functional insights into peptidoglycan access for the lytic amidase LytA of Streptococcus pneumoniae P Mellroth, T Sandalova, A Kikhney, F Vilaplana, D Hesek, M Lee, ... MBio 5 (1), 10.1128/mbio. 01120-13, 2014 | 82 | 2014 |
| Analysis of IAV replication and co-infection dynamics by a versatile RNA viral genome labeling method D Dou, I Hernández-Neuta, H Wang, H Östbye, X Qian, S Thiele, ... Cell reports 20 (1), 251-263, 2017 | 67 | 2017 |
| Impact of AmpC derepression on fitness and virulence: the mechanism or the pathway? M Pérez-Gallego, G Torrens, J Castillo-Vera, B Moya, L Zamorano, ... MBio 7 (5), 10.1128/mbio. 01783-16, 2016 | 61 | 2016 |
| Peptidoglycan recognition proteins with amidase activity in early deuterostomes (Echinodermata) G Coteur, P Mellroth, C De Lefortery, D Gillan, P Dubois, D Communi, ... Developmental & Comparative Immunology 31 (8), 790-804, 2007 | 57 | 2007 |
| Gradient acoustic focusing of sub-micron particles for separation of bacteria from blood lysate D Van Assche, E Reithuber, W Qiu, T Laurell, B Henriques-Normark, ... Scientific reports 10 (1), 3670, 2020 | 52 | 2020 |
| Control of intestinal Nod2-mediated peptidoglycan recognition by epithelium-associated lymphocytes CU Duerr, NH Salzman, A Dupont, A Szabo, BH Normark, S Normark, ... Mucosal immunology 4 (3), 325-334, 2011 | 28 | 2011 |
| The crystal structure of the major pneumococcal autolysin LytA in complex with a large peptidoglycan fragment reveals the pivotal role of glycans for lytic activity T Sandalova, M Lee, B Henriques‐Normark, D Hesek, S Mobashery, ... Molecular microbiology 101 (6), 954-967, 2016 | 23 | 2016 |
| Membrane particles evoke a serotype-independent cross-protection against pneumococcal infection that is dependent on the conserved lipoproteins MalX and PrsA AR Narciso, F Iovino, S Thorsdottir, P Mellroth, M Codemo, C Spoerry, ... Proceedings of the National Academy of Sciences 119 (23), e2122386119, 2022 | 11 | 2022 |
| THCz: Small molecules with antimicrobial activity that block cell wall lipid intermediates E Reithuber, T Wixe, KC Ludwig, A Müller, H Uvell, F Grein, AEG Lindgren, ... Proceedings of the National Academy of Sciences 118 (47), e2108244118, 2021 | 7 | 2021 |
| The bactericidal fatty acid mimetic 2CCA-1 selectively targets pneumococcal extracellular polyunsaturated fatty acid metabolism E Reithuber, P Nannapaneni, O Rzhepishevska, AEG Lindgren, ... Mbio 11 (6), 10.1128/mbio. 03027-20, 2020 | 4 | 2020 |
