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Daryl Ewald Klein
Daryl Ewald Klein
Verified email at yale.edu
Title
Cited by
Cited by
Year
Specificity and promiscuity in phosphoinositide binding by pleckstrin homology domains
JM Kavran, DE Klein, A Lee, M Falasca, SJ Isakoff, EY Skolnik, ...
Journal of Biological Chemistry 273 (46), 30497-30508, 1998
5651998
The pleckstrin homology domains of dynamin isoforms require oligomerization for high affinity phosphoinositide binding
DE Klein, A Lee, DW Frank, MS Marks, MA Lemmon
Journal of Biological Chemistry 273 (42), 27725-27733, 1998
2571998
Structural basis for negative cooperativity in growth factor binding to an EGF receptor
D Alvarado, DE Klein, MA Lemmon
Cell 142 (4), 568-579, 2010
1992010
Argos inhibits epidermal growth factor receptor signalling by ligand sequestration
DE Klein, VM Nappi, GT Reeves, SY Shvartsman, MA Lemmon
Nature 430 (7003), 1040-1044, 2004
1802004
Structure of a dengue virus envelope protein late-stage fusion intermediate
DE Klein, JL Choi, SC Harrison
Journal of virology 87 (4), 2287-2293, 2013
1352013
Functional Selectivity in Cytokine Signaling Revealed Through a Pathogenic EPO Mutation
Cell 168 (6), 1053-1064. e15, 2017
1112017
ErbB2 resembles an autoinhibited invertebrate epidermal growth factor receptor
D Alvarado, DE Klein, MA Lemmon
Nature 461 (7261), 287-291, 2009
1072009
Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells
EL Bao, SK Nandakumar, X Liao, AG Bick, J Karjalainen, M Tabaka, ...
Nature 586 (7831), 769-775, 2020
1022020
High-affinity binding of a FYVE domain to phosphatidylinositol 3-phosphate requires intact phospholipid but not FYVE domain oligomerization
VG Sankaran, DE Klein, MM Sachdeva, MA Lemmon
Biochemistry 40 (29), 8581-8587, 2001
932001
Sequential conformational rearrangements in flavivirus membrane fusion
LH Chao, DE Klein, AG Schmidt, JM Peña, SC Harrison
Elife 3, e04389, 2014
922014
Structural basis for EGFR ligand sequestration by Argos
DE Klein, SE Stayrook, F Shi, K Narayan, MA Lemmon
Nature 453 (7199), 1271-1275, 2008
652008
Computational analysis of EGFR inhibition by Argos
GT Reeves, R Kalifa, DE Klein, MA Lemmon, SY Shvartsman
Developmental biology 284 (2), 523-535, 2005
502005
Kinetics of receptor tyrosine kinase activation define ERK signaling dynamics
A Kiyatkin, IK van Alderwerelt van Rosenburgh, DE Klein, MA Lemmon
Science Signaling 13 (645), eaaz5267, 2020
462020
Infantile myelofibrosis and myeloproliferation with CDC42 dysfunction
JM Verboon, D Mahmut, AR Kim, M Nakamura, NJ Abdulhay, ...
Journal of clinical immunology 40, 554-566, 2020
312020
Massively parallel base editing to map variant effects in human hematopoiesis
JD Martin-Rufino, N Castano, M Pang, EI Grody, S Joubran, A Caulier, ...
Cell 186 (11), 2456-2474. e24, 2023
292023
Structural basis for ligand reception by anaplastic lymphoma kinase
T Li, SE Stayrook, Y Tsutsui, J Zhang, Y Wang, H Li, A Proffitt, SG Krimmer, ...
Nature 600 (7887), 148-152, 2021
252021
Structural basis of neurohormone perception by the receptor tyrosine kinase Torso
S Jenni, Y Goyal, M von Grotthuss, SY Shvartsman, DE Klein
Molecular cell 60 (6), 941-952, 2015
172015
Monospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B. 1.617
L Peng, Y Hu, MC Mankowski, P Ren, RE Chen, J Wei, M Zhao, T Li, ...
Nature communications 13 (1), 1638, 2022
132022
7SK methylation by METTL3 promotes transcriptional activity
M Perez-Pepe, AW Desotell, H Li, W Li, B Han, Q Lin, DE Klein, Y Liu, ...
Science advances 9 (19), eade7500, 2023
62023
ALK inhibitors increase ALK expression and sensitize neuroblastoma cells to ALK. CAR-T cells
E Bergaggio, WT Tai, A Aroldi, C Mecca, E Landoni, M Nüesch, I Mota, ...
Cancer cell 41 (12), 2100-2116. e10, 2023
42023
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