Nicolas Manel
Nicolas Manel
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Induction of intestinal Th17 cells by segmented filamentous bacteria
II Ivanov, K Atarashi, N Manel, EL Brodie, T Shima, U Karaoz, D Wei, ...
Cell 139 (3), 485-498, 2009
Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine
II Ivanov, R de Llanos Frutos, N Manel, K Yoshinaga, DB Rifkin, RB Sartor, ...
Cell host & microbe 4 (4), 337-349, 2008
The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt
N Manel, D Unutmaz, DR Littman
Nature immunology 9 (6), 641-649, 2008
Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles
M Colombo, C Moita, G Van Niel, J Kowal, J Vigneron, P Benaroch, ...
Journal of cell science 126 (24), 5553-5565, 2013
Aicardi–Goutières syndrome and the type I interferonopathies
YJ Crow, N Manel
Nature Reviews Immunology 15 (7), 429-440, 2015
ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death
M Raab, M Gentili, H de Belly, HR Thiam, P Vargas, AJ Jimenez, ...
Science 352 (6283), 359-362, 2016
Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity
JR Huh, MWL Leung, P Huang, DA Ryan, MR Krout, RRV Malapaka, ...
Nature 472 (7344), 486-490, 2011
The ubiquitous glucose transporter GLUT-1 is a receptor for HTLV
N Manel, FJ Kim, S Kinet, N Taylor, M Sitbon, JL Battini
Cell 115 (4), 449-459, 2003
A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells
N Manel, B Hogstad, Y Wang, DE Levy, D Unutmaz, DR Littman
Nature 467 (7312), 214-217, 2010
Inherited STING-activating mutation underlies a familial inflammatory syndrome with lupus-like manifestations
N Jeremiah, B Neven, M Gentili, I Callebaut, S Maschalidi, ...
The Journal of clinical investigation 124 (12), 5516-5520, 2014
The capsids of HIV-1 and HIV-2 determine immune detection of the viral cDNA by the innate sensor cGAS in dendritic cells
X Lahaye, T Satoh, M Gentili, S Cerboni, C Conrad, I Hurbain, A El Marjou, ...
Immunity 39 (6), 1132-1142, 2013
The nucleus acts as a ruler tailoring cell responses to spatial constraints
AJ Lomakin, CJ Cattin, D Cuvelier, Z Alraies, M Molina, GPF Nader, ...
Science 370 (6514), eaba2894, 2020
Transmission of innate immune signaling by packaging of cGAMP in viral particles
M Gentili, J Kowal, M Tkach, T Satoh, X Lahaye, C Conrad, M Boyron, ...
Science 349 (6253), 1232-1236, 2015
Erythrocyte Glut1 triggers dehydroascorbic acid uptake in mammals unable to synthesize vitamin C
A Montel-Hagen, S Kinet, N Manel, C Mongellaz, R Prohaska, JL Battini, ...
Cell 132 (6), 1039-1048, 2008
Lentiviral Vpx accessory factor targets VprBP/DCAF1 substrate adaptor for cullin 4 E3 ubiquitin ligase to enable macrophage infection
S Srivastava, SK Swanson, N Manel, L Florens, MP Washburn, ...
PLoS pathogens 4 (5), e1000059, 2008
Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytes
S Cerboni, N Jeremiah, M Gentili, U Gehrmann, C Conrad, ...
Journal of Experimental Medicine 214 (6), 1769-1785, 2017
The N-terminal domain of cGAS determines preferential association with centromeric DNA and innate immune activation in the nucleus
M Gentili, X Lahaye, F Nadalin, GPF Nader, EP Lombardi, S Herve, ...
Cell reports 26 (9), 2377-2393. e13, 2019
Susceptibility of human Th17 cells to human immunodeficiency virus and their perturbation during infection
A El Hed, A Khaitan, L Kozhaya, N Manel, D Daskalakis, W Borkowsky, ...
The Journal of infectious diseases 201 (6), 843-854, 2010
NONO detects the nuclear HIV capsid to promote cGAS-mediated innate immune activation
X Lahaye, M Gentili, A Silvin, C Conrad, L Picard, M Jouve, E Zueva, ...
Cell 175 (2), 488-501. e22, 2018
Mutations in COPA lead to abnormal trafficking of STING to the Golgi and interferon signaling
A Lepelley, MJ Martin-Niclós, M Le Bihan, JA Marsh, C Uggenti, GI Rice, ...
Journal of Experimental Medicine 217 (11), e20200600, 2020
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